Inositol and metformin for women with PCOS and insulin resistance
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study compares two different diets (Mediterranean and low-carbohydrate) combined with either inositol or metformin to see which combination helps manage PCOS symptoms and insulin resistance in women who are overweight or obese.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 20 and 40 years old
- You have been diagnosed with PCOS
- You have insulin resistance, either newly diagnosed or within the last 3 months
- Your body mass index (BMI) is between 30 and 40
- You are not currently pregnant or breastfeeding
- You are not taking any regular medications, including hormonal birth control (for at least 3 months), and you do not have diabetes, chronic diseases, or psychiatric conditions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether acupuncture or the diabetes medicine metformin can improve insulin resistance in women with PCOS. It may help with hormone-related symptoms and metabolic health, comparing the two approaches against usual care for non-PCOS controls.
This study tests whether a specific nutrition plan can help women with PCOS improve their health. You would follow a guided diet and have check-ins to see how it affects your symptoms and well-being.
This study tests if a diet low in quickly digested carbs (low glycemic index) and high in fiber can help women with PCOS who are overweight. You'll follow this eating plan and not change your exercise, to see how it affects your PCOS symptoms over several months.
This study tests if a keto diet can improve symptoms of PCOS. You'll follow your normal routine while researchers monitor changes.
This study tests whether a Mediterranean diet combined with synbiotics (a type of supplement that helps gut health) can improve PCOS symptoms in women who are overweight. If you have PCOS and are looking for a way to manage it through diet, this trial might be a good fit.
This trial compares two medicines, metformin and myo-inositol, to see which works better for managing PCOS symptoms like irregular periods, excess hair, and acne. It may help you if you have PCOS and haven't started treatment yet.
Hear when a new Insulin Resistance trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.