Clinical trials
Insulin Resistance clinical trials
Below are recruiting insulin resistance clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07516509Recruiting
How muscle cells respond to blood sugar in different body types
This research study examines how muscle cells handle blood sugar differently depending on whether someone is lean or has obesity, and whether their body resists insulin. Researchers will take small muscle samples to understand the genetic differences, which may help develop better treatments for insulin resistance and metabolic health.
Orlando, FloridaAges 30–65 - NCT06163768Recruiting
Insulin's role in non-diabetic heart attack patients
This study looks at how insulin resistance affects recovery after a heart attack or unstable angina in people without diabetes. It may help understand why some patients have worse outcomes.
Ho Chi Minh City, FiveAges 18–60 - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT07287514Recruiting
Test of two oils on metabolism in adults with insulin resistance
This study compares an oil rich in linoleic acid (a type of omega-6 fat) against a blend oil to see which one better improves metabolism and heart health in people with insulin resistance. It may help if you have insulin resistance and at least one heart risk factor like belly fat, low good cholesterol, or high blood pressure.
Santiago, Santiago MetropolitanAges 20–60 - NCT07678736Recruiting
Muscle health and early heart risk study
This study looks at how your muscles might show early signs of future heart or blood sugar problems. You'll have a muscle check and follow some meal guidelines.
Ghent, East FlandersAges 20–30 - NCT02193295Recruiting
Testing how changing fats affects insulin resistance
This study tests how “lipid” (fat) changes in the body affect insulin resistance, which is when the body doesn’t respond to insulin as well as it should. Because it’s done in healthy people, it’s mainly looking at basic biology and may help guide future treatments.
New Haven, ConnecticutAges 18–90 - NCT07408479Recruiting
How starch digestion affects blood sugar and health in insulin resistance
This trial studies how different types of starch (carbohydrates) affect blood sugar control, inflammation, and gut health in people with insulin resistance. You may benefit if you are overweight, have insulin resistance, and are willing to follow a specific diet for 2 months.
LyonAges 18–75 - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65 - NCT04883515Recruiting
Glutamine drink for insulin resistance and bowel symptoms
This trial studies whether taking an oral glutamine supplement can improve insulin resistance and reduce bowel-related problems in people with obesity and irritable bowel syndrome. It may help your blood sugar regulation and digestive comfort if you meet the criteria.
RouenAges 18–65 - NCT05743868Recruiting
Study of how insulin resistance affects blood fats
This study looks at how differences in insulin resistance may change how the liver makes triglycerides (a type of blood fat). It may help researchers understand why some people have higher triglycerides and how to target them better.
AmsterdamAges 18–65 - NCT06609200Recruiting
Electro-acupuncture for obesity with insulin resistance
This study tests whether electro-acupuncture (a type of acupuncture with mild electric pulses) can help people with obesity and insulin resistance improve their health. It may be an option if you're looking for a non-drug treatment for weight and blood sugar control.
SingaporeAges 21–65 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT04578652RecruitingPhase 3
Test fiber plus metformin for teen weight and insulin resistance
This trial studies whether adding fiber to metformin helps teens with severe obesity and insulin resistance improve how their bodies handle sugar. You might consider it if you’re a teen who isn’t yet diagnosed with type 2 diabetes and meets the specific lab and health criteria.
Edmonton, AlbertaAges 12–18 - NCT06806345RecruitingPhase 1/Phase 2
Oxygen therapy for insulin resistance after menopause
This trial tests whether hyperbaric oxygen therapy can help reduce insulin resistance in postmenopausal women. It may offer a new way to improve blood sugar control.
Cairo, Cairo GovernorateAges 55–65 - NCT05833217Recruiting
Study for persistent COVID symptoms with insulin resistance
This trial studies people who have ongoing effects after COVID (often called PASC) and may be related to weight and insulin resistance. It may help researchers find better ways to understand the condition and improve treatment.
Palo Alto, CaliforniaAges 18–80 - NCT07545538Enrolling by invitation
Carbohydrate Drink Before Surgery to Help Kids Recover
This study tests whether drinking a special carbohydrate solution before surgery helps children's bodies handle the stress of the operation better and recover more smoothly. The drink may reduce complications related to blood sugar control after surgery.
Yogyakarta, Special Region of YogyakartaAges 2–16 - NCT07780513Recruiting
Genetics of muscle insulin resistance study
This study looks at how genes affect the way muscles use sugar, which can help understand insulin resistance. Participants will have tests and procedures, including a glucose drink test and a muscle biopsy, to see how their bodies handle sugar.
San Antonio, TexasAges 18–75 - NCT06138821Recruiting
Endoscopic sleeve gastroplasty for obesity and MASH
This study tests if a procedure called endoscopic sleeve gastroplasty helps people with obesity and a liver condition called MASH lose weight and improve their liver health. It might be an option if you have both obesity and MASH and haven't had weight-loss surgery before.
Boston, MassachusettsAges 18 years+ - NCT07307677Recruiting
Melatonin and metformin for PCOS with insulin resistance
This study tests if adding melatonin to metformin can improve insulin resistance and other health markers in women with PCOS who have insulin resistance. It compares the combination to metformin alone.
Dhaka, ShahbagAges 18–35 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT03818178Recruiting
Study of gut-delivered fats and insulin resistance
This study looks at how sending certain fats through the intestine affects “insulin resistance,” a condition where the body doesn’t use insulin as well. If you qualify, you may receive a controlled lipid (fat) delivery as part of measuring body fat handling and related body chemistry.
Rochester, MinnesotaAges 18–55 - NCT02647827RecruitingPhase 2
Acupuncture or metformin for insulin resistance in PCOS
This study tests whether acupuncture or the diabetes medicine metformin can improve insulin resistance in women with PCOS. It may help with hormone-related symptoms and metabolic health, comparing the two approaches against usual care for non-PCOS controls.
BeijingAges 18–40 - NCT07226128Recruiting
Can therapy help HIV patients with depression and insulin resistance?
This study tests if cognitive behavioral therapy (a type of talk therapy) can improve how your body handles sugar (insulin resistance) for people living with HIV who also have depression. You may join if you have HIV, are on stable HIV meds, feel depressed, and do not have diabetes.
Indianapolis, IndianaAges 18 years+
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Insulin Resistance trials by city
Studies with a site in or near these metro areas.
Insulin Resistance trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for insulin resistance?
- Yes. Clin2 currently lists 124 recruiting insulin resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a insulin resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a insulin resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.