Precision medicine trial for low blood oxygen in hospital
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests two medicines, simvastatin and baricitinib, to see if they can help people with severe breathing problems in the hospital. The goal is to find which medicine works best for each patient, possibly improving their recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are currently in the hospital with critically low oxygen levels in your blood.
- You must have a condition called ARDS or a pandemic-related illness that affects your breathing.
- You need to be on a breathing machine, a mask that helps you breathe, or high-flow oxygen through your nose.
- If you are being considered for simvastatin, you must not be taking certain other medicines and must not have severe kidney disease.
- If you are being considered for baricitinib, you must not have a very low white blood cell count, active tuberculosis, or be on certain immune-suppressing medicines.
- You must not be pregnant for either treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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