MRI study of linaclotide for cystic fibrosis
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study uses MRI scans to look at how the drug linaclotide affects the intestines in people with cystic fibrosis. You'll take the drug or a placebo and have MRI scans after eating special meals to see if the drug helps with gut function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of cystic fibrosis.
- You must be between 18 and 60 years old.
- You must be willing to follow the study protocol, including fasting, taking the study drug or placebo, undergoing MRI scans, and eating special meals (including blue muffins).
- You must not be pregnant, planning to become pregnant, or breastfeeding.
- You must not have had intravenous or oral antibiotics (except preventive ones like azithromycin) in the last 2 weeks.
- You must not have had intestinal surgery (except appendix removal) or have other digestive disorders unrelated to CF.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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