Clin2
NCT07784309Possibly a fitEnrolling by invitation

Cell therapy for CD7-positive blood cancer

Acute T Cell Lymphoblastic LeukemiaLymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryAcute Myeloid Leukemia (AML)T Cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study tests a new cell therapy for people with certain types of blood cancer that have returned or not responded to standard treatments. The therapy uses immune cells modified to target a marker called CD7 on cancer cells. It may help reduce or eliminate the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
13 people
Ages
3 years to 70 years
Study type
Interventional

Who can take part

  • Your cancer must be CD7-positive (at least 30% of cells show CD7 by special testing).
  • You must have a blood cancer that has come back or not responded to treatment.
  • You must be between 3 and 70 years old.
  • Your liver, kidneys, and other organs must be working well enough for the study.
  • You must not have any active serious infections, heart problems, or other major illnesses.
  • You must agree to use effective birth control if you or your partner can have children.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07109518Recruiting· Phase 1
CD7 CAR T-Cell Therapy for Blood Cancers That Return or Don't Respond

This trial tests a new CAR T-cell therapy targeting CD7, a protein on some blood cancer cells. It is designed for patients whose T-cell leukemia/lymphoma or other CD7-positive blood cancer has not responded to standard treatments or has returned.

Tianjin, Tianjin Municipality
NCT07106723Recruiting· Phase 2
Study of stem cell transplant and CD7-CART for T-cell lymphoma

This trial combines your own stem cells (collected before) with a special immune cell therapy (CD7-CART) to treat T-cell lymphoma or leukemia. It may help people with high-risk or hard-to-treat disease.

Tianjin, Tianjin Municipality
NCT07117305Not yet recruiting· Phase 1/Phase 2
CD7-targeted cell therapy with stem cell transplant for T-cell lymphoma

This trial tests a treatment that uses your own immune cells (CAR-T) engineered to find and attack CD7 on T-cell lymphoma cells, followed by a stem cell transplant to rebuild your immune system. It is for people with certain types of T-cell lymphoma that have come back or not responded to standard treatments.

Zhengzhou, Henan
NCT06316427Recruiting· Phase 1/Phase 2
CD7 CAR-T therapy for T-cell cancers that returned

This trial tests a new kind of immunotherapy called CD7 CAR-T therapy for people with T-cell cancers (like leukemia or lymphoma) that have come back or not responded to treatment. The CAR-T cells are made from your own immune cells or a donor's, and they are designed to find and destroy cancer cells that carry the CD7 marker.

Beijing, Beijing Municipality
NCT06925464Recruiting· Phase 1/Phase 2
Modified immune cells for T-cell lymphoma

This trial tests a new treatment where your own immune cells are modified to find and attack CD7-positive T-cell lymphoma cells. It is for people whose lymphoma has not responded to standard treatments.

Beijing, Beijing Municipality
NCT04033302Not yet recruiting· Phase 1/Phase 2
Multi-CAR T cell therapy for CD7-positive blood cancers

This trial tests a new type of immune cell therapy (multi-CAR T cells) designed to target and kill cancer cells that have a marker called CD7. It may help people with certain blood cancers that have not responded well to other treatments.

Shenzhen, Guangdong

Hear when a new T-cell Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.