Accelerated brain stimulation plus study drug for depression
Part of Mental health clinical trials.
This trial tests a single day of ultra-accelerated brain stimulation (TMS) combined with a single dose of a study drug (NRX-101) to see if it can quickly reduce depression symptoms. It is an early-phase study, meaning the treatment is new and being tested for safety and effectiveness.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have moderate to severe depression (scoring at least 20 on a standard depression scale).
- You must not have a history of bipolar disorder (manic or hypomanic episodes).
- You must not have a significant current alcohol or drug use problem that could interfere with the study.
- You must not have a history of seizures or brain injury that raises your seizure risk.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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