Platelet-rich plasma plus hyaluronic acid for knee osteoarthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests whether adding platelet-rich plasma (PRP) to hyaluronic acid injections improves knee osteoarthritis pain and function better than hyaluronic acid alone. You may be eligible if you have moderate knee osteoarthritis and no other knee problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have knee osteoarthritis diagnosed by a doctor.
- Your knee X-ray shows grade II or III osteoarthritis.
- Your pain in the affected knee is 4 or higher on a 0-10 scale.
- Your pain in the opposite knee is 2 or lower on a 0-10 scale.
- You have not had knee surgery in the past year.
- You have not had knee injections (cortisone, hyaluronic acid, PRP) within the last 6 months.
- You have not used oral steroids (like prednisone) within the last 2 weeks.
- You do not have inflammatory arthritis (like rheumatoid arthritis) or autoimmune disease.
- You are not pregnant or breastfeeding.
- Your body mass index (BMI) is less than 40.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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