Clot-busting drug for stroke within 4.5 hours
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a clot-busting drug called recombinant human prourokinase for people having an ischemic stroke (a stroke from a blocked blood vessel). The drug is given through an IV within 4.5 hours of symptoms to help restore blood flow and potentially reduce disability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You had a stroke caused by a blocked blood vessel (ischemic stroke) and can start treatment within 4.5 hours of symptoms starting.
- You do not have uncontrolled high blood pressure (systolic ≥185 mmHg or diastolic ≥110 mmHg).
- You do not have active bleeding or high risk of bleeding (e.g., recent surgery or major injury).
- You have not had a stroke, severe head trauma, or heart attack in the last 3 months.
- You do not have a history of bleeding in the brain, and a CT scan shows no bleeding now.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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