Investigational medicine for sleep apnea in people with obesity
Part of Brain & nervous system, Hormones & metabolism, Lungs & breathing clinical trials.
This study tests an investigational medicine (HDM1005) for people who have both obesity and obstructive sleep apnea (where breathing stops during sleep) and who already use a CPAP machine. The goal is to see if the medicine can reduce breathing pauses and improve sleep quality compared to a placebo.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 75 years old
- Have a body mass index (BMI) of 28 or higher (obesity)
- Be diagnosed with obstructive sleep apnea (OSA), with moderate to severe breathing pauses during sleep
- Have used a CPAP or similar breathing machine for at least 3 months and plan to keep using it during the trial
- Have not changed your weight by more than 5% in the last 90 days
- Not have diabetes (except pregnancy-related diabetes that went away)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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