Adding dexmedetomidine to knee injection for total knee replacement pain
Part of Pain clinical trials.
This study tests whether adding a sedative medicine called dexmedetomidine to the usual numbing injection around the knee can improve pain relief and recovery after a total knee replacement. It is a pilot (small early-stage) trial to see if this approach is safe and worth studying more.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are having a total knee replacement on one knee (not both)
- You are generally healthy or have mild health issues (ASA class I–III)
- You have no known allergies to local anesthetics or dexmedetomidine
- You have not used opioid pain medication within 24 hours before surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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