Testing a sedative added to numbing medicine for knee replacement pain
Part of Pain clinical trials.
This trial tests whether adding a sedative medicine (dexmedetomidine) to the standard numbing injection around the knee can improve pain control after total knee replacement. It might help you have less pain and need fewer opioids.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are having elective total knee replacement on one knee only
- Your overall health is stable (ASA grade I–III)
- You are not allergic to numbing medicines or the study drug dexmedetomidine
- You have not used opioid pain medicine in the 24 hours before surgery
- You are willing and able to give written consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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