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NCT07816068Possibly a fitNot yet recruiting

Testing remimazolam anesthesia to reduce memory problems after aortic arch surgery

Aortic Aneurysm of the Proximal ArchAortic Aneurysms ArchAortic Arch DiseasePostoperative Delirium (POD)POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINEPostoperative Delirium

Treatments studied

Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.

This trial compares a newer anesthetic, remimazolam, to standard care to see if it helps prevent short-term memory or thinking problems after surgery on the aortic arch (a major artery in the chest). It also checks blood markers of brain inflammation. If you are having this type of surgery, this study might help protect your memory.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
80 people
Ages
19 years and older
Study type
Interventional

Who can take part

  • You must be 19 years old or older.
  • You need to be scheduled for a surgery to replace part or all of your aortic arch, where the surgeon will stop blood flow to the brain or use a special method to keep the brain supplied with blood.
  • You must not already have memory problems (a standard memory test score of 24 or higher).
  • You must not have had a stroke or bleeding in the brain in the last 3 months.
  • You must not have severe liver disease, kidney failure on dialysis, or a history of drug or alcohol abuse.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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