Clin2
NCT07819669Possibly a fitNot yet recruiting

Surgery with or without heat ablation for multiple lung cancer

Multiple Primary Lung Cancers

Part of Cancer, Lungs & breathing clinical trials.

This study compares two ways to treat multiple lung cancer tumors that are all on the same side of the chest. One way is surgery alone, and the other is surgery plus a heat-based treatment that destroys the additional tumor(s). The goal is to see if combining the two approaches removes the cancer more completely while preserving as much healthy lung as possible.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
160 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are 18 to 80 years old.
  • You have been diagnosed with more than one lung cancer tumor in the same lung (same side).
  • The main tumor can be removed with surgery, and the additional tumor(s) are suitable for both surgical removal and a treatment that uses heat to destroy the tumor (radiofrequency ablation).
  • You are in generally good health with no major heart or lung problems.
  • You have not had lung surgery before, and your cancer has not spread to lymph nodes or other parts of the body.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07398027Not yet recruiting
Freezing and heat treatment for small lung cancers before surgery

This study tests a new way to treat small lung cancers during a scope procedure, followed by surgery. The treatment uses freezing and heat to destroy the tumor, and the study checks how safe and effective it is.

Zurich, Raemistrasse
NCT06503744Recruiting
Comparing two minimally invasive heat treatments for early lung cancer

This trial compares two types of radiofrequency ablation (a heat-based treatment) for early-stage lung cancer that is located in the outer parts of the lung. One approach uses a needle through the chest wall, the other uses a bronchoscope through the airways. The goal is to see which works better for people who cannot have surgery.

Shanghai, Shanghai Municipality
NCT07741344Not yet recruiting· Phase 2
Comparing bronchoscopic microwave ablation and surgery for early-stage lung cancer

This study looks at two ways to treat early-stage lung cancer: using heat from a tiny probe passed through the airways to kill the tumor (microwave ablation), or surgery to remove the tumor and some surrounding tissue. The goal is to find which approach is more effective and safer for people with this type of lung cancer.

Hong Kong
NCT05053802Recruiting· Phase 2
Microwave tumor ablation plus immunotherapy for multiple lung cancers

This Phase 2 trial studies whether combining microwave ablation (a procedure to destroy lung tumors) with an immune checkpoint inhibitor can control multiple early lung cancers safely. It also aims to see how well the immune treatment helps after ablation, in people whose cancers have not spread.

Shanghai, Shanghai Municipality
NCT07698990Not yet recruiting
Comparing two lung surgeries for early-stage lung cancer

This study compares two types of lung cancer surgery for early-stage tumors: removing only the part of the lung with the tumor (segmentectomy) versus removing the entire lobe (lobectomy). It aims to see if the smaller surgery works just as well and might be easier to recover from.

Shanghai, Shanghai Municipality
NCT02468024Recruiting· Phase 3
Surgery or focused radiation for early lung cancer

This study compares two treatments—removing only part of the lung (sublobar resection) versus a focused radiation approach (stereotactic ablative radiotherapy)—for early-stage non-small cell lung cancer. It aims to see which option works better with fewer problems for the right patients.

La Jolla, California

Hear when a new Multiple Primary Lung Cancers trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.