Gene therapy for type 1 diabetes
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This study tests a new gene therapy (VV-14300) that aims to help people with type 1 diabetes make insulin again. It might improve blood sugar control and reduce the need for insulin.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old.
- You must have been diagnosed with type 1 diabetes for at least 5 years.
- You must be using an automated insulin delivery system (a smart pump or closed-loop system) for at least 3 months.
- Your A1c (average blood sugar level) must be between 7% and 10%.
- Your kidney function must be normal (eGFR greater than 60).
- You must not have severe diabetes complications, recurrent ketoacidosis, or serious heart disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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