Clin2
NCT07862751Possibly a fitNot yet recruiting

Ultrasound and photoacoustic imaging to monitor treatment response in triple negative breast cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8Triple-Negative Breast Carcinoma

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests whether a new imaging approach using ultrasound and photoacoustic imaging can detect early whether the tumor is responding to standard immunotherapy and chemotherapy before surgery. It aims to improve treatment monitoring for patients with stage II-III triple negative breast cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
32 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have stage II or stage III triple negative breast cancer.
  • You are eligible to receive the standard KEYNOTE-522 treatment (immunotherapy plus chemotherapy).
  • Your cancer has not spread to other parts of the body.
  • If you could become pregnant, you must have a negative pregnancy test before starting and use an approved birth control method during the trial.
  • You must be able to give informed consent to participate.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05812807Recruiting· Phase 3
Pembrolizumab versus monitoring after triple-negative breast cancer response

This trial checks whether giving pembrolizumab (an immunotherapy) after surgery helps people with triple-negative breast cancer reduce the chance of the cancer coming back, compared with close monitoring only. It’s for patients who had no remaining invasive cancer after neoadjuvant chemotherapy plus pembrolizumab.

Birmingham, Alabama
NCT07610525Not yet recruiting· Phase 2
Optimizing early triple-negative breast cancer treatment with imaging and blood tests

This trial tests whether using blood tests and imaging during chemotherapy and immunotherapy can help guide treatment for early-stage triple-negative breast cancer. It aims to improve outcomes by adjusting treatment based on how the cancer responds.

Houston, Texas
NCT04428528Recruiting
Ultrasound-like pictures that track breast tumors during chemotherapy

This study uses a special light-based imaging scan to learn more about breast masses and how tumors may respond to chemotherapy before surgery. The scan is meant to help doctors better characterize tumors and potentially track treatment response.

Toronto, Ontario
NCT04134780Recruiting
Ultrasound tests to spot early breast cancer treatment response

This study uses special ultrasound imaging (and may use MRI results) to look for early signs of how locally advanced breast cancer responds to chemotherapy, with or without radiation. If the imaging changes early, it could help doctors adjust treatment sooner.

Houston, Texas
NCT07327021Recruiting· Phase 2
MRI-Guided treatment reduction for stage 2-3 triple-negative breast cancer

This trial tests if using MRI scans can safely reduce the amount of chemotherapy and immunotherapy needed before surgery for triple-negative breast cancer. All patients will receive the standard KEYNOTE-522 regimen, but the treatment may be tailored based on MRI results.

Tel Aviv
NCT05020860Recruiting· Phase 2
Study how early breast cancer responds on imaging and under a microscope

This Phase 2 study looks at how well early breast cancer shrinks with treatment and how that matches with what doctors find after surgery under the microscope. The goal is to learn better ways to predict and assess treatment success.

Houston, Texas

Hear when a new Anatomic Stage II Breast Cancer AJCC v8 trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.