Comparing two versions of a brain scan dye
Part of Brain & nervous system, Mental health clinical trials.
This trial compares two formulations of a PET scan dye (flutemetamol F 18) to see if they work equally well for imaging amyloid plaques in the brain, which may help diagnose Alzheimer's disease or other causes of memory decline. Participation involves one or two brain scans and some blood tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 50 years old.
- You must have been referred for a PET scan with VIZAMYL to check for amyloid plaques in the brain, possibly to help evaluate memory problems or to see if you qualify for Alzheimer's treatments.
- You must be able to lie still on your back in a scanner for about 60 minutes at a time (roughly 2.5 hours total per scan session, with a break).
- If you can become pregnant or get someone pregnant, you must agree to use effective birth control and not donate eggs or sperm during the study and for a period after your last scan.
- You must be willing to fast (no food or drink except water and needed medications) for at least 6 hours before each scan day.
- You must not have significant kidney or liver problems, diabetes, or known allergies to the scan dye ingredients.
- You must not be taking or planning to take any Alzheimer's disease-modifying drugs (like anti-amyloid drugs) during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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