Clin2
NCT07877597Likely a fitNot yet recruiting

Adding radiation to chemotherapy for high-risk colon cancer

Locally Advanced Colon CancerpMMR

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests whether adding a short course of radiation to chemotherapy before surgery helps improve outcomes for people with high-risk colon cancer. Radiation is given along with chemotherapy, and the study compares this to chemotherapy alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
480 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have colon cancer that has spread through the bowel wall or to nearby lymph nodes, but not to distant organs.
  • Your tumor is more than 15 cm from the anal verge (confirmed by colonoscopy).
  • Your cancer is pMMR or MSS (a specific genetic marker) confirmed by a test.
  • You have not had any prior cancer treatment for this disease.
  • Your overall health is good (able to care for yourself and up and about more than 50% of waking hours).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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