Clinical trials
ACL clinical trials
Below are recruiting acl clinical trials, each written for real people, not researchers. We’re tracking 129 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04825587Recruiting
Study after first ACL reconstruction in children
This study looks at children’s outcomes after their first ACL ligament surgery using a specific graft (quadriceps tendon). It may help doctors compare and improve how ACL repairs are done in growing kids with open or closing growth plates.
Chicago, IllinoisAges Up to 18 years - NCT05391672Recruiting
Study for early surgery after a partial ACL tear
This trial looks at treatment options for people with a partial ACL ligament tear in the knee, including both recent and long-standing injuries. It may help to clarify the best early approach for healing and knee function, especially when there are no other ligament injuries.
AsyutAges 15–50 - NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT06235736Recruiting
Do ACL tears cause weakness in the soleus muscle?
This study looks at whether people with ACL tears have weakness in a specific calf muscle called the soleus. If you have an ACL tear, you will do strength tests to compare with healthy individuals.
LiverpoolAges 18–55 - NCT06357091Recruiting
ACL repair with Shark Screw or standard screw
This trial compares two types of screws used to hold a new ACL in place: a Shark Screw and a standard biocomposite screw. It may help if you have a torn ACL that needs surgery.
Schwaz, TyrolAges 18 years+ - NCT06430775Recruiting
Long-term ACL recovery after surgery
This study is looking at how well the ACL heals after surgery in the long term. It helps researchers understand recovery patterns, so you may get a closer look at your knee's healing process.
Roeselare, West-VlaanderenAges 18–40 - NCT06542705Recruiting
Internal brace for ACL reconstruction with BTB graft
This trial tests whether adding an internal brace (a strong suture tape) during ACL reconstruction with a BTB graft helps improve knee stability and recovery. It is for people ages 18 to 35 with a first-time ACL tear who are otherwise healthy.
New York, New YorkAges 18–35 - NCT04462458Recruiting
Study tracking outcomes after ACL reconstruction surgery
This is a study that follows adults who had an ACL tear treated with ACL reconstruction. It helps understand how the surgical device/material performs in real-world care.
InnsbruckAges 18 years+ - NCT03441659Recruiting
ACL reconstruction recovery study using clinical outcome tracking
This study looks at outcomes after surgery to repair the ACL (a knee ligament that helps stabilize the joint). If you’re having ACL reconstruction, the trial may help doctors understand what factors lead to better recovery.
Bologna, ItaliaAges 18–60 - NCT06147427Recruiting
ACL reconstruction with or without Lemaire procedure
This study compares two surgical techniques for repairing a torn ACL: standard ACL reconstruction alone versus ACL reconstruction plus a Lemaire procedure (an extra side-stabilizing repair). It aims to see which approach provides better knee stability for active patients over at least 2 years.
LyonAges 18–50 - NCT06529692Recruiting
Split-belt treadmill training after ACL reconstruction
This study tests whether walking on a special split-belt treadmill (where each belt moves at a different speed) can help improve how your knee moves and feels after ACL reconstruction. The goal is to see if this training leads to better long-term knee health.
Ann Arbor, MichiganAges 14–45 - NCT06727344Recruiting
ACL recovery with blood flow restriction therapy
This study tests whether adding blood flow restriction (gentle pressure applied to the upper leg during exercise) to standard treatment can help heal a completely torn ACL. If you have a full ACL tear and can speak Greek, you may be able to join.
NicosiaAges 18–40 - NCT06819696Recruiting
Comparing two ACL reconstruction surgery methods
This trial compares two ways of doing anterior cruciate ligament (ACL) reconstruction surgery: using a tourniquet to control bleeding, or using a special sheath that allows fluid to flow in and out. The goal is to see which method works better during surgery.
Reims, MarneAges 18 years+ - NCT06979804Recruiting
Comparing knee surgery outcomes with special fabric products
This study compares how well people do after anterior cruciate ligament (ACL) surgery, with or without also repairing the meniscus, using a special fabric product. It aims to see if the fabric helps improve recovery and outcomes for people with these common knee injuries.
Westmont, IllinoisAges 16–65 - NCT07049484Recruiting
ACL surgery with extra ligament reinforcement study
This study looks at how well an ACL reconstruction works when it also includes a second procedure (LET) to give extra support to the knee. It may help people who need this specific type of surgery have better stability and movement afterward.
BolognaAges 18–50 - NCT07171346Enrolling by invitation
Muscle stimulator after ACL reconstruction
This study tests whether a special muscle-stimulating device worn after ACL reconstruction surgery can help your knee recover strength faster. If you qualify, you will use the device at home for a few weeks and your recovery will be checked regularly.
Kansas City, KansasAges 15–50 - NCT06975306Recruiting
Bone Graft for Kneecap Defect in ACL Surgery
This study looks at how a bone graft used to fill a gap in the kneecap affects healing and recovery after ACL reconstruction. Researchers want to see if the graft helps the bone heal better and improves your knee function.
Phoenix, ArizonaAges 18–40 - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT06178497Recruiting
5-Year Check-In After ACL Repair
This study checks on people who had ACL (anterior cruciate ligament) repair surgery 5 years ago to see how well their knee is doing. It looks at a specific type of ACL tear (a 'proximal' tear) and helps doctors understand long-term results.
Lille, Choisir Une RégionAges 18 years+ - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT06311058Recruiting
Protein supplement study for ACL surgery recovery
This trial tests whether a protein supplement can help you recover strength and muscle after ACL surgery. You will continue your standard rehab and take a protein drink daily for several weeks.
Houston, TexasAges 16–40 - NCT07190456Recruiting
Study on fear of movement after ACL surgery
This study looks at different types of fear people might feel after ACL surgery, especially when doing jumping tasks. It aims to help understand these fears better so rehab can be improved.
Caparica, AlmadaAges 18–35 - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45
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Common questions
- Are there clinical trials for acl?
- Yes. Clin2 currently lists 129 recruiting acl studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.