Clinical trials
Anterior Cruciate Ligament (ACL) Tear clinical trials
Below are recruiting anterior cruciate ligament (acl) tear clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT06195423Recruiting
Stopping knee arthritis after an ACL tear
This study tests a home exercise program to prevent knee arthritis after an ACL tear. If you had ACL surgery 9 to 36 months ago and still have some knee symptoms, this program may help protect your knee in the long run.
Vancouver, British ColumbiaAges 16–35 - NCT06442319Recruiting
PRP after ACL reconstruction
This trial tests if injecting platelet-rich plasma (a concentration of your own blood platelets) after ACL reconstruction helps with healing and reduces pain. It's for people who recently had ACL surgery and want to try an extra treatment to improve recovery.
TorunAges 18–45 - NCT07762989Recruiting
Ankle recovery after ACL surgery using a leg tendon graft
This study examines how well the ankle and lower leg recover after ACL reconstruction when the graft is taken from the peroneus longus tendon. By participating, you help doctors learn how this procedure affects ankle strength and function, which may improve future care.
Çankaya, AnkaraAges 18–55 - NCT06631690Recruiting
ACL surgery and ankle joint function study
This study looks at how ACL reconstruction knee surgery might affect the mechanics of your ankle joint. It aims to understand if the surgery changes how your ankle moves and works, which could help improve rehabilitation.
CairoAges 15–45 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65 - NCT06858930Recruiting
Navigation system for ACL reconstruction
This trial tests a special computer navigation system to help surgeons place the new ACL graft more precisely during knee reconstruction. If you have a torn ACL and are between 18 and 80, this study might help improve your surgery outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT07306221Recruiting
Balance training after ACL surgery using visual guides
This study tests if a special video-based balance training program helps people recover knee function better after ACL reconstruction surgery. It is designed for patients who had surgery within the past year using their own hamstring tendon.
BeijingAges 18–45 - NCT05174611RecruitingPhase 2
Vitamin D to strengthen the thigh after ACL surgery
This Phase 2 study tests whether taking vitamin D can improve thigh (quadriceps) muscle strength after ACL reconstruction. It targets people with low vitamin D levels that persist after surgery and weaker thigh strength on the injured side.
Hong KongAges 18–40 - NCT07185802Recruiting
PRP injection for recent ACL injury
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
DhakaAges 18–50 - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT06979804Recruiting
Comparing knee surgery outcomes with special fabric products
This study compares how well people do after anterior cruciate ligament (ACL) surgery, with or without also repairing the meniscus, using a special fabric product. It aims to see if the fabric helps improve recovery and outcomes for people with these common knee injuries.
Westmont, IllinoisAges 16–65 - NCT06974526RecruitingPhase 2
Study of a dissolvable implant for recovery after ACL surgery
This study tests whether a dissolvable implant that releases a medication called oxandrolone can improve recovery after ACL surgery. Oxandrolone may help strengthen the new ligament and speed up healing.
Fortaleza, CearáAges 18–60 - NCT06956339Recruiting
Bracing vs Surgery for First-Time ACL Tear
This trial compares a new bracing treatment (Cross Bracing Protocol) versus standard surgery for people who have torn their ACL for the first time. It aims to see which approach leads to better recovery and fewer complications.
Melbourne, VictoriaAges 16–40 - NCT06948591Recruiting
BioBrace® Support in ACL Reconstruction Surgery
This study looks at how well a special tissue support called BioBrace® works when used during ACL reconstruction surgery. It follows patients who have already had the surgery or are planning to have it, to see how their knee recovers over time.
New Haven, ConnecticutAges 14–70 - NCT06875427RecruitingPhase 3
Nerve block vs no block for ACL surgery in kids
This trial tests whether a nerve block (a numbing shot) before ACL reconstruction helps young patients have less pain and better recovery compared to no block.
Hamilton, OntarioAges 10–18 - NCT06818201Recruiting
Brain stimulation for ACL surgery recovery
This study tests if a gentle, noninvasive brain stimulation called tDCS can improve how your brain controls leg muscles and speeds up recovery after ACL surgery.
Valencia, ValenciaAges 16–40 - NCT06368544Recruiting
Early walking training after ACL knee surgery
This trial studies whether starting walking exercises earlier after ACL reconstruction can help protect the knee cartilage from wearing down. It may be a good fit if you are having your first ACL surgery at Peking University Third Hospital and your knee has already healed from the initial injury.
BeijingAges 18–40 - NCT06668376Enrolling by invitation
Incrediwear recovery products after ACL repair surgery
This study is testing Incrediwear recovery products (like sleeves or wraps) to see if they help reduce pain and swelling and improve healing after ACL repair. If you're having ACL surgery and meet the health requirements, you may be able to join.
Denton, TexasAges 18–65 - NCT05342441Recruiting
Choosing the best ligament graft for ACL repair
This study looks at how different “grafts” (tissue used to rebuild the ACL) affect outcomes after first-time ACL reconstruction. It may help personalize graft choice for people who want to return to physical activity.
HvidovreAges 18–40
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Common questions
- Are there clinical trials for anterior cruciate ligament (acl) tear?
- Yes. Clin2 currently lists 36 recruiting anterior cruciate ligament (acl) tear studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anterior cruciate ligament (acl) tear trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anterior cruciate ligament (acl) tear trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- ACL - Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Tear
- Anterior Cruciate Ligament (ACL) Reconstruction
- Anterior Cruciate Ligament Injuries
- Anterior Cruciate Ligament Rupture
- Anterior Cruciate Ligament Reconstruction
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- Anterior Cruciate Ligament
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.