Clinical trials
ACL Tear clinical trials
Below are recruiting acl tear clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06235736Recruiting
Do ACL tears cause weakness in the soleus muscle?
This study looks at whether people with ACL tears have weakness in a specific calf muscle called the soleus. If you have an ACL tear, you will do strength tests to compare with healthy individuals.
LiverpoolAges 18–55 - NCT06430775Recruiting
Long-term ACL recovery after surgery
This study is looking at how well the ACL heals after surgery in the long term. It helps researchers understand recovery patterns, so you may get a closer look at your knee's healing process.
Roeselare, West-VlaanderenAges 18–40 - NCT05391672Recruiting
Study for early surgery after a partial ACL tear
This trial looks at treatment options for people with a partial ACL ligament tear in the knee, including both recent and long-standing injuries. It may help to clarify the best early approach for healing and knee function, especially when there are no other ligament injuries.
AsyutAges 15–50 - NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT06178484Recruiting
Surgery versus rehabilitation for a torn ACL
This study compares two ways to treat a tear of the anterior cruciate ligament (ACL) near the top of the knee. It looks at whether having surgery is better than a non-surgical approach with physical therapy. You may be eligible if your tear is recent and you have no other knee injuries.
Lille, Choisir Une RégionAges 18 years+ - NCT04825587Recruiting
Study after first ACL reconstruction in children
This study looks at children’s outcomes after their first ACL ligament surgery using a specific graft (quadriceps tendon). It may help doctors compare and improve how ACL repairs are done in growing kids with open or closing growth plates.
Chicago, IllinoisAges Up to 18 years - NCT07015541Recruiting
Quadriceps strengthening after ACL reconstruction
This trial is for people who have had ACL surgery on one knee only (not both knees) and want to strengthen their quadriceps. It tests if adding special muscle stimulation or blood flow restriction training helps recovery.
Sunnyvale, CaliforniaAges 13–17 - NCT06781021Enrolling by invitation
ACL surgery: Clearer view with medication or tourniquet?
This study compares two ways to control bleeding during ACL knee surgery: a medication called tranexamic acid (TXA) versus a tourniquet. The goal is to see which method gives surgeons a clearer view inside the knee, which may help them do a better job.
Kingston, JamaicaAges 18 years+ - NCT06486246Recruiting
Nerve block options for ACL surgery recovery
This trial compares two types of nerve blocks for pain relief after ACL reconstruction. It aims to find which approach provides better comfort and faster recovery.
BarcelonaAges 18–50 - NCT04295148Recruiting
Compare brace and rehab for ACL reconstruction
This study compares two ways of rehabilitating the knee after ACL rupture repair. It’s meant to see which approach helps people return to their prior sport more safely and effectively.
Stockholm, Stockholm CountyAges 16–40 - NCT07318272Recruiting
ACL surgery repair vs. reconstruction recovery study
This study compares how well people recover after two different types of ACL surgery: reconstruction (using a graft) and primary repair (stitching the torn ligament). It will help doctors understand which approach leads to better knee function long-term. Participants must be between 18 and 40, had their ACL surgery at Gazi University, and be at least one year past surgery.
Ankara, ÇankayaAges 18–40 - NCT06875427RecruitingPhase 3
Nerve block vs no block for ACL surgery in kids
This trial tests whether a nerve block (a numbing shot) before ACL reconstruction helps young patients have less pain and better recovery compared to no block.
Hamilton, OntarioAges 10–18 - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT06096259RecruitingPhase 2
Preventing knee arthritis after ACL injury
This trial tests whether metformin, a common diabetes medicine, can prevent arthritis after an ACL injury. If you are planning to have ACL surgery soon, you may be able to join.
Atlanta, GeorgiaAges 18–45 - NCT06195423Recruiting
Stopping knee arthritis after an ACL tear
This study tests a home exercise program to prevent knee arthritis after an ACL tear. If you had ACL surgery 9 to 36 months ago and still have some knee symptoms, this program may help protect your knee in the long run.
Vancouver, British ColumbiaAges 16–35 - NCT06948591Recruiting
BioBrace® Support in ACL Reconstruction Surgery
This study looks at how well a special tissue support called BioBrace® works when used during ACL reconstruction surgery. It follows patients who have already had the surgery or are planning to have it, to see how their knee recovers over time.
New Haven, ConnecticutAges 14–70 - NCT07423767Recruiting
Counseling before ACL surgery to reduce fear and improve recovery
This study tests whether a short counseling program before ACL surgery can help reduce fear of movement and improve recovery. If you are preparing for your first ACL reconstruction, this program may help you feel more confident and get back to activities sooner.
Beijing, None SelectedAges 18–45 - NCT07636278Recruiting
Augmented Reality guidance for ACL knee surgery
This trial tests whether using augmented reality (special computer graphics overlaid on surgical video) during ACL reconstruction surgery helps surgeons perform the procedure more accurately. You would undergo standard knee surgery, but the surgeon would have real-time computer guidance to assist with precision.
Milan, MichiganAges 18 years+ - NCT06979804Recruiting
Comparing knee surgery outcomes with special fabric products
This study compares how well people do after anterior cruciate ligament (ACL) surgery, with or without also repairing the meniscus, using a special fabric product. It aims to see if the fabric helps improve recovery and outcomes for people with these common knee injuries.
Westmont, IllinoisAges 16–65 - NCT04572256RecruitingEarly Phase 1
Montelukast after ACL surgery to protect knee cartilage
This early trial tests whether montelukast, a tablet used for allergies, can help protect knee cartilage after ACL surgery. It is specifically for people who have a meniscus injury along with their ACL tear.
Lexington, KentuckyAges 25–50 - NCT06668376Enrolling by invitation
Incrediwear recovery products after ACL repair surgery
This study is testing Incrediwear recovery products (like sleeves or wraps) to see if they help reduce pain and swelling and improve healing after ACL repair. If you're having ACL surgery and meet the health requirements, you may be able to join.
Denton, TexasAges 18–65 - NCT06041763Recruiting
Bridge-enhanced ACL repair for meniscus repair
This study tests a special bridge implant to help heal a torn meniscus during surgery. It may help improve recovery and reduce the need for additional surgeries.
New York, New YorkAges 18–75 - NCT07366619Recruiting
MADI ACL study: a new MRI method for ligament repair
This trial tests a new MRI technique called Magic Angle Direction Imaging (MADI) to see if it can give better images of the knee before ligament repair surgery. It may help doctors plan your surgery more accurately.
LondonAges 18–65 - NCT06631690Recruiting
ACL surgery and ankle joint function study
This study looks at how ACL reconstruction knee surgery might affect the mechanics of your ankle joint. It aims to understand if the surgery changes how your ankle moves and works, which could help improve rehabilitation.
CairoAges 15–45
Hear when a new ACL Tear trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for acl tear?
- Yes. Clin2 currently lists 24 recruiting acl tear studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl tear trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl tear trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.