Clinical trials
ACL Reconstruction clinical trials
Below are recruiting acl reconstruction clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06542705Recruiting
Internal brace for ACL reconstruction with BTB graft
This trial tests whether adding an internal brace (a strong suture tape) during ACL reconstruction with a BTB graft helps improve knee stability and recovery. It is for people ages 18 to 35 with a first-time ACL tear who are otherwise healthy.
New York, New YorkAges 18–35 - NCT07404046Recruiting
Comparing tendon grafts for ACL surgery
This trial compares two types of grafts using the semitendinosus tendon for ACL reconstruction. It aims to see if adding a part of the tendon's muscle improves healing and stability after surgery.
ZagrebAges 18–50 - NCT03441659Recruiting
ACL reconstruction recovery study using clinical outcome tracking
This study looks at outcomes after surgery to repair the ACL (a knee ligament that helps stabilize the joint). If you’re having ACL reconstruction, the trial may help doctors understand what factors lead to better recovery.
Bologna, ItaliaAges 18–60 - NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT06357091Recruiting
ACL repair with Shark Screw or standard screw
This trial compares two types of screws used to hold a new ACL in place: a Shark Screw and a standard biocomposite screw. It may help if you have a torn ACL that needs surgery.
Schwaz, TyrolAges 18 years+ - NCT06819696Recruiting
Comparing two ACL reconstruction surgery methods
This trial compares two ways of doing anterior cruciate ligament (ACL) reconstruction surgery: using a tourniquet to control bleeding, or using a special sheath that allows fluid to flow in and out. The goal is to see which method works better during surgery.
Reims, MarneAges 18 years+ - NCT07190456Recruiting
Study on fear of movement after ACL surgery
This study looks at different types of fear people might feel after ACL surgery, especially when doing jumping tasks. It aims to help understand these fears better so rehab can be improved.
Caparica, AlmadaAges 18–35 - NCT07662850Recruiting
Rehab after ACL surgery: blood flow training and soft tissue work
This study tests if combining blood flow restriction training with a special manual technique (IASTM) helps reduce pain, build strength, improve knee movement, and lower fear of re-injury after ACL reconstruction. It is for people who are 8 to 16 weeks past surgery and already have good knee bending.
Lahore, Punjab ProvinceAges 18–40 - NCT06147427Recruiting
ACL reconstruction with or without Lemaire procedure
This study compares two surgical techniques for repairing a torn ACL: standard ACL reconstruction alone versus ACL reconstruction plus a Lemaire procedure (an extra side-stabilizing repair). It aims to see which approach provides better knee stability for active patients over at least 2 years.
LyonAges 18–50 - NCT07049484Recruiting
ACL surgery with extra ligament reinforcement study
This study looks at how well an ACL reconstruction works when it also includes a second procedure (LET) to give extra support to the knee. It may help people who need this specific type of surgery have better stability and movement afterward.
BolognaAges 18–50 - NCT04295148Recruiting
Compare brace and rehab for ACL reconstruction
This study compares two ways of rehabilitating the knee after ACL rupture repair. It’s meant to see which approach helps people return to their prior sport more safely and effectively.
Stockholm, Stockholm CountyAges 16–40 - NCT07090616Recruiting
Comparing two knee braces after ACL surgery
This study compares two different knee braces used after ACL surgery to see which one helps people recover better. If you are having your first ACL reconstruction, you may be able to join and help find out if one brace works better than the other.
Chicago, IllinoisAges 18 years+ - NCT07475351Recruiting
Comparing two grafts for ACL reconstruction
This trial compares two types of grafts to rebuild the ACL in the knee, to see if one leads to better results. It is for active athletes with a recent ACL tear and healthy knees.
Granada, GranadaAges 12–40 - NCT07523854Recruiting
Knee Strength Recovery After ACL Surgery: Comparing Graft Types
This study compares how well the knee recovers its strength after ACL (anterior cruciate ligament) reconstruction surgery using two different graft options. By tracking your progress over time, researchers hope to understand which graft type helps you regain the most strength.
AnkaraAges 13–45 - NCT04825587Recruiting
Study after first ACL reconstruction in children
This study looks at children’s outcomes after their first ACL ligament surgery using a specific graft (quadriceps tendon). It may help doctors compare and improve how ACL repairs are done in growing kids with open or closing growth plates.
Chicago, IllinoisAges Up to 18 years - NCT06974526RecruitingPhase 2
Hormone implant for ACL surgery recovery
This trial tests a small implant that slowly releases the hormone oxandrolone to help you recover strength and function faster after ACL reconstruction surgery. It is for people who are already active and have no major health problems that could interfere with the medicine.
Fortaleza, CearáAges 18–60 - NCT07171346Enrolling by invitation
Muscle stimulator after ACL reconstruction
This study tests whether a special muscle-stimulating device worn after ACL reconstruction surgery can help your knee recover strength faster. If you qualify, you will use the device at home for a few weeks and your recovery will be checked regularly.
Kansas City, KansasAges 15–50 - NCT06341192Recruiting
Comparing two ways to reconstruct the ACL
This trial compares two different techniques for ACL surgery (single bundle vs. double bundle) to see which one works better. If you're planning to have ACL surgery, you may be able to join.
Taoyuan, taoyuanAges 18 years+ - NCT06505525Recruiting
ACL reconstruction: adding extra support vs standard surgery
This trial compares two surgical techniques for ACL reconstruction. The standard method repairs the ACL inside the knee joint, while the new method also adds extra support outside the joint. The study aims to see which approach gives better stability and recovery for people with specific risk factors, like being a young athlete or having a chronic ACL tear.
São Paulo, São PauloAges 14–40 - NCT06529692Recruiting
Split-belt treadmill training after ACL reconstruction
This study tests whether walking on a special split-belt treadmill (where each belt moves at a different speed) can help improve how your knee moves and feels after ACL reconstruction. The goal is to see if this training leads to better long-term knee health.
Ann Arbor, MichiganAges 14–45 - NCT06206200Recruiting
Thinking and moving after ACL surgery
This study looks at how doing a thinking task at the same time as a walking or balance task affects recovery in people who have had ACL reconstruction surgery. It may help you understand what to expect during later stages of rehab.
Roeselare, West-VlaanderenAges 18–40 - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT06955026Recruiting
Hockey slideboard and blood flow restriction for ACL rehab
This trial tests if using a hockey slideboard with blood flow restriction (a special band that limits blood flow during exercise) helps recovery after ACL surgery. It may improve muscle strength and function faster.
Odorheiu Secuiesc, RomaniaAges 18–45 - NCT06430775Recruiting
Long-term ACL recovery after surgery
This study is looking at how well the ACL heals after surgery in the long term. It helps researchers understand recovery patterns, so you may get a closer look at your knee's healing process.
Roeselare, West-VlaanderenAges 18–40
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Common questions
- Are there clinical trials for acl reconstruction?
- Yes. Clin2 currently lists 93 recruiting acl reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acl reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acl reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.