Clinical trials
Addiction clinical trials
Below are recruiting addiction clinical trials, each written for real people, not researchers. We’re tracking 213 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05277714Recruiting
Neurofeedback for food addiction in people with obesity
This trial tests whether brain-training feedback using near-infrared sensors (a painless light-based brain measure) can reduce food addiction behaviors in people with obesity. If you qualify for obesity surgery and have food addiction signs, you may be offered this therapy and monitored during the study.
RennesAges 18–55 - NCT05338801Recruiting
Study menthol effects in e-cigarette users
This study tests how menthol in e-cigarettes affects addiction-related feelings and exposure. You may be asked to visit a lab and temporarily stop vaping before each session.
Miami, FloridaAges 21–35 - NCT05391113Recruiting
Brain-training reward system study for adults with autism
This study tests a “reward system” approach in the brain for adults with autism (and also for adults with food addiction and for healthy volunteers). It may help researchers understand brain and behavior differences and whether this kind of task-based training is safe and useful.
ToursAges 18 years+ - NCT05435300Recruiting
tDCS study using brain scans in schizophrenia
This trial tests whether a non-invasive brain stimulation approach (tDCS) changes brain connections in people with schizophrenia. It also uses specialized scans to look for changes in the brain that could help explain how treatment works.
Toronto, OntarioAges 18 years+ - NCT05437809Recruiting
Study how people’s brains respond to ultra-processed foods
This study looks at how brain and body reward signals change after eating different ultra-processed foods. It may help researchers understand how food choices and metabolism relate to weight and mood in some people.
Philadelphia, PennsylvaniaAges 18–65 - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+ - NCT05490589Recruiting
Parenting program for parents affected by alcohol use
This trial tests a structured parenting program for parents of children ages 4 to 12 when the parent (or spouse) has an alcohol use disorder. It may help families by supporting parenting skills and improving day-to-day family functioning.
BrestAges 18 years+ - NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT05515354RecruitingPhase 4
Smoking quit plan matched to your menstrual cycle phase
This Phase 4 study tests a smoking-quit treatment plan timed to your menstrual cycle. It may help you quit smoking and learn how quitting support works for people who menstruate regularly.
Toronto, OntarioAges 18–40 - NCT05529927RecruitingPhase 2
Dexamphetamine given long-acting to reduce cocaine use
This Phase 2 study tests whether a long-acting form of dexamphetamine can reduce cocaine use in people with moderate to severe cocaine use disorder. It also checks safety, including heart and mental health side effects, while you attend study visits regularly.
The HagueAges 18 years+ - NCT05534815Recruiting
Long-term support for opioid use disorder treatment
This study looks at long-term treatment support for people receiving medicine-assisted treatment for opioid use disorder. It may help by testing an approach to improve long-term outcomes while you receive buprenorphine or methadone.
Marquette, MichiganAges 18 years+ - NCT05563363Recruiting
Home-based treatment for severe addiction problems
This trial tests a home-based treatment approach for adults with severe substance use problems. It may help you and your care team manage addiction with structured support while you stay at home.
GenevaAges 18 years+ - NCT05583747Recruiting
Brain stimulation therapy with guidance for treatment-resistant depression
This study tests a type of brain stimulation (guided iTBS) to improve depression when standard antidepressant treatments haven’t helped. It also checks that the treatment is safe for people who can meet the study and scan safety requirements.
Toronto, OntarioAges 18–65 - NCT05627492Recruiting
DBT booster sessions for youth at bipolar risk
This study adds short “booster” sessions to Dialectical Behavior Therapy (DBT) for young people who already took part in a prior DBT study, including those with bipolar symptoms or strong family risk. It aims to see if extra DBT support helps mood and coping over time.
Toronto, OntarioAges 14–25 - NCT05702021Recruiting
Using counseling incentives to reduce stimulant use in opioid clinics
This trial tests a counseling approach called “contingency management,” which uses structured incentives to reduce stimulant use. It’s meant for people receiving treatment in specialty addiction programs and/or newly starting opioid-use medication who also use stimulants.
Chicago, IllinoisAges 18 years+ - NCT05704582Recruiting
Avatar vs supportive sessions to cut cannabis use
This study compares two types of talking/learning sessions—one using an “avatar” (computer-based character) and one using regular supportive sessions—to reduce cannabis use. It is meant for adults with psychotic disorders who also meet criteria for cannabis use disorder.
Montreal, QuebecAges 18 years+ - NCT05738174Recruiting
High-dose brain stimulation to help treat alcohol addiction
This trial studies a type of noninvasive brain stimulation to reduce alcohol dependence and help people drink less or stop. You may be offered an accelerated treatment schedule, with regular check-ins and questionnaires to track progress.
RegensburgAges 18–65 - NCT05744479RecruitingPhase 4
Metformin to reduce weight gain from antipsychotic medicines
This trial tests whether metformin can help adults with intellectual disability who gained weight from long-term antipsychotic medicines. If you qualify, you may be assigned metformin to improve weight and related health measures.
Toronto, OntarioAges 16–65 - NCT05748990Recruiting
Brain insulin differences in schizophrenia and thinking
This study tests whether unusual insulin action in the brain is linked to thinking problems and body/metabolic issues in schizophrenia. It may help researchers understand the cause and identify targets for future treatments.
Toronto, OntarioAges 17–45 - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT05861752Recruiting
Study of sexual risk behaviors and mental health patterns
This case-control study looks at people with specific sexual behavior-related conditions (like certain paraphilias, compulsive sexual behavior, or sex during sleep) to understand factors linked with risk for sexual violence. The goal is to learn what patterns may be involved so better help and prevention strategies can be developed.
Stockholm, Stockholm CountyAges 18 years+ - NCT05943171Recruiting
App-based CBT for substance dependence and relationship aggression
This study tests an app-guided version of CBT (a structured talk-therapy approach) against standard CBT to help people with substance dependence and recent verbal aggression in an intimate relationship. You may be screened to see if you fit both the substance use and relationship aggression parts of the trial.
Rochester, New YorkAges 18–65 - NCT05964010Recruiting
Parent-and-teen program for teen health visits
This trial offers a structured support program for teenagers and their primary caregiver during a primary care visit. It may help by testing an approach that connects youth and families with resources and support starting at the clinic visit.
New York, New YorkAges 12–17 - NCT05973838Recruiting
Telemedicine support plus recovery coaching for multiple drug use
This study tests whether adding peer recovery support to a phone/video treatment program helps people stay in treatment longer and reduce polysubstance use. It focuses on adults in opioid use disorder care who have used other non-prescribed substances in the last three months.
Washington D.C., District of ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for addiction?
- Yes. Clin2 currently lists 213 recruiting addiction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a addiction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a addiction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.