Clinical trials
Adjuvant Treatment clinical trials
Below are recruiting adjuvant treatment clinical trials, each written for real people, not researchers. We’re tracking 130 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07371611RecruitingPhase 3
Sintilimab plus chemo before and after surgery for advanced oral cancer
This trial tests whether adding an immunotherapy drug (sintilimab) to standard chemotherapy before and after surgery can improve outcomes for people with advanced oral squamous cell carcinoma. The treatment is given first to shrink the tumor, then again after surgery to help prevent recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07368803RecruitingPhase 1/Phase 2
Personalized mRNA vaccine for bile duct cancer after surgery
This trial tests a personalized mRNA vaccine (iNeo-Vac-R01) made from your tumor's unique markers to help prevent cancer from coming back after surgery for bile duct or other digestive cancers. It may be an option if standard treatments have stopped working or caused side effects.
Hangzhou, ZhejiangAges 18–75 - NCT07351903RecruitingPhase 1
GK01 with or without chemo after surgery for solid tumors
This trial tests an investigational drug called GK01, given alone or with chemotherapy, after surgery to remove a solid tumor. The goal is to see if it helps prevent the cancer from coming back.
TianjinAges 18–70 - NCT07339904Recruiting
Bowel Function After Rectal Cancer Surgery
This study follows people with rectal cancer who have surgery to remove part of the rectum. It looks at how bowel function changes over time, and whether different treatments before surgery affect recovery.
Edegem, AntwerpAges 18 years+ - NCT07331883RecruitingPhase 2
Sintilimab and bevacizumab after surgery for ruptured liver cancer
This trial tests whether combining two immune-based drugs (sintilimab and a bevacizumab biosimilar) after surgery can prevent liver cancer from returning in people whose tumor had ruptured. It’s for patients who have had a complete surgical removal of a ruptured hepatocellular carcinoma and are now cancer-free on imaging.
Sanming, FujianAges 18–75 - NCT04996017RecruitingPhase 3
Atezolizumab after surgery for malignant pleural mesothelioma
This study tests whether atezolizumab given after surgery and chemotherapy can lower the risk of mesothelioma coming back compared with a placebo. It may help by boosting the immune system to control remaining microscopic cancer cells.
Meldola, ITAòYAges 18 years+ - NCT07295938RecruitingPhase 2
Traditional Chinese medicine as an add-on treatment for mycobacterium abscessus in the lungs
This study tests if adding traditional Chinese medicine to standard treatment helps people with a lung infection called Mycobacterium abscessus. It may improve recovery and reduce side effects.
BeijingAges 18–75 - NCT07266480RecruitingPhase 2
Adalimumab after surgery for esophageal cancer
This trial tests whether adding adalimumab (a medicine that helps the immune system) after surgery can prevent esophageal cancer from coming back. It's for people who have already had their cancer completely removed by surgery.
Shijiazhuang, HebeiAges 18 years+ - NCT06643585RecruitingPhase 3
Comparing T-DXd to standard therapy for molecular relapse in early breast cancer
This trial compares a new drug called Trastuzumab-Deruxtecan (T-DXd) to standard treatment for people with early breast cancer whose cancer has come back at a molecular level (detected by a blood test) but hasn't spread to other parts of the body. The goal is to see if T-DXd can prevent the cancer from returning.
UlmAges 18–75 - NCT07131514RecruitingPhase 2
Combination therapy for pancreatic cancer before and after surgery
This trial tests if giving a combination of four drugs before and after surgery can help treat pancreatic cancer. The drugs include HRS-4642, gemcitabine, nab-paclitaxel, and adebrelimab. It may help shrink the tumor before surgery and lower the chance of cancer coming back afterward.
ShanghaiAges 18–80 - NCT06294847RecruitingPhase 3
Ursodeoxycholic acid for better recovery after retinal detachment surgery
This trial tests if adding ursodeoxycholic acid (a bile acid medication) to standard surgery can protect the retina and improve vision after a retinal detachment. It's for people who need vitrectomy surgery and have a detached retina involving the macula.
ParisAges 18 years+ - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT07071038RecruitingPhase 2
Switching medication to relieve side effects from aromatase inhibitors
This trial tests whether switching to a different aromatase inhibitor or using standard treatments works better for managing side effects in breast cancer survivors. It aims to help you stay on hormone therapy longer with fewer discomforts.
Lebanon, New HampshireAges 18 years+ - NCT07051694Recruiting
Ear nerve stimulation for sepsis patients in the ICU
This trial tests a non-invasive ear stimulation device (taVNS) as an extra treatment for sepsis in the ICU. It may help reduce inflammation and improve recovery.
ChongqingAges 18–80 - NCT07018947RecruitingPhase 2
Atezolizumab and bevacizumab before and after surgery for liver cancer
This trial tests whether adding two drugs (atezolizumab and bevacizumab) before and after surgery can lower the chance of liver cancer coming back in people with high-risk HCC. You must be eligible for surgical removal of your tumor.
Badalona, BarcelonaAges 18 years+ - NCT06992882RecruitingPhase 3
Comparing two chemo regimens with Herceptin for early breast cancer
This trial tests if taking oral chemotherapy pills with trastuzumab (Herceptin) works as well as IV chemo (paclitaxel) with Herceptin after surgery for HER2-positive, lymph node-negative early breast cancer. It aims to find a more convenient treatment option.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT04771728RecruitingPhase 4
Probiotics added to treatment for bacterial vaginosis
This study tests whether adding probiotics to standard care helps treat bacterial vaginosis (BV) and possibly lowers the chance of it coming back. You would be placed into a study group to compare probiotic treatment with the other approach.
Shenzhen, GuangdongAges 18–55 - NCT06830720Recruiting
Kisqali with hormone therapy for early-stage breast cancer
This study looks at how well Kisqali (ribociclib) combined with hormone therapy works after surgery for people with early-stage HR+ HER2- breast cancer that has a high chance of coming back. It aims to gather real-world data on different treatment options.
Wiener Neustadt, Lower AustriaAges 18–100 - NCT06830889RecruitingPhase 3
BL-M07D1 vs T-DM1 for HER2-positive breast cancer after neoadjuvant therapy
This trial tests whether a new drug called BL-M07D1 works better than an existing drug, T-DM1, for people with HER2-positive breast cancer who still have cancer cells after initial treatment (neoadjuvant therapy). The goal is to prevent the cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT06807749Recruiting
Adjuvant treatment for premenopausal breast cancer
This trial looks back at premenopausal women with early-stage, hormone-positive, HER2-negative breast cancer who had surgery and an Oncotype DX test, to see how different treatments affected their outcomes. If you fit this group, your past medical records could help researchers learn more about the best treatments.
Roma, Antonella PalazzoAges Up to 60 years - NCT06766578RecruitingPhase 2
Low-dose radiation plus immunotherapy and chemo before gastric cancer surgery
This trial tests a new combination of low-dose radiation, an immunotherapy drug (tirelizumab), and chemotherapy (SOX) given before surgery for locally advanced gastric or gastroesophageal junction cancer. The goal is to see if this approach can shrink tumors more effectively.
Jinan, ShandongAges 18–75 - NCT06761846RecruitingPhase 2
Immunotherapy and chemo after stomach cancer surgery
This trial tests whether adding the immunotherapy drug sintilimab to standard chemotherapy after surgery can help prevent stage III stomach or gastroesophageal junction cancer from coming back. You may qualify if you had D2 surgery and your tumor tested positive for PD-L1.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06587061RecruitingPhase 2
HRS-4642 plus AG before and after surgery for pancreatic cancer
This trial tests a combination of two medications (HRS-4642 and AG) given before and after surgery for pancreatic cancer that can be removed. The goal is to see if this treatment helps prevent the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06592599RecruitingPhase 2
Drug combo for EBV-related nasopharyngeal cancer
This trial tests a combination of three drugs (gemcitabine, docetaxel, and toripalimab) as a first treatment for a type of nasopharyngeal cancer linked to the Epstein-Barr virus. The goal is to see if this combination helps shrink tumors before other treatments like radiation.
Palo Alto, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for adjuvant treatment?
- Yes. Clin2 currently lists 130 recruiting adjuvant treatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adjuvant treatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adjuvant treatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.