Clinical trials
Adolescence clinical trials
Below are recruiting adolescence clinical trials, each written for real people, not researchers. We’re tracking 932 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05316948Recruiting
Study of mental health and sexuality in teens
This study asks young people in psychiatric care about mental health and sexuality, using their study information to understand how these may relate. You may be able to join whether or not you take psychiatric (mental health) medicines, as long as it doesn’t interfere with urgent/emergency needs.
Vence, Alpes MaritimesAges 15 years+ - NCT06477848Enrolling by invitation
Improving care for teens with opioid use disorder in pediatric clinics
This study looks at how to better support teens with opioid use disorder in pediatric primary care. It involves training clinic staff and gathering feedback from both providers and patients.
Indianapolis, IndianaAges 12 years+ - NCT06211517Recruiting
Teens' experiences with medication for anorexia
This study explores how adolescents with anorexia feel about taking antidepressants or antipsychotics. It aims to understand their experiences to improve care.
Paris, IDFAges 12 years+ - NCT05819034Recruiting
Non-surgical care for mild adolescent scoliosis
This trial looks at a non-surgical (conservative) approach to managing mild scoliosis in teens. It may help by improving comfort, posture control, and how the curve changes over time without surgery.
Mecca, Mecca RegionAges 10–17 - NCT06439277RecruitingPhase 3
Tirzepatide for teens with obesity and related health problems
This study tests a medication called tirzepatide (a once-weekly injection) to help teenagers with obesity and related health conditions lose weight. It aims to see if the drug is safe and effective for this age group.
Los Angeles, CaliforniaAges 12–17 - NCT06413979Recruiting
Family support program for teens with substance use and mood or anxiety issues
This trial offers a family support program for teens with both substance use and internalizing problems like depression or anxiety. The goal is to help you and your caregiver work together to manage symptoms and improve well-being.
Jacksonville, FloridaAges 13–21 - NCT06365892Recruiting
Open-label placebo for pain after scoliosis surgery
This trial tests whether taking a placebo pill that you know is a placebo (open-label placebo) can help reduce pain after spinal fusion surgery for scoliosis. It compares the placebo to standard care in adolescents aged 11-17.
San Francisco, CaliforniaAges 10–18 - NCT06341634Enrolling by invitation
Suicide ideation surveillance in teens
This study follows adolescents aged 11 to 16 to better understand and track suicidal thoughts. It may help improve care for teens with or without these thoughts.
Santiago de Compostela, A CoruñaAges 11–16 - NCT06310434Enrolling by invitation
Understanding compassion in teens and young adults facing end-of-life
This study looks at how teenagers and young adults understand compassion and human connection when facing the end of life. It may help improve how schools and families support young people during difficult times.
Murcia, MUAges 12–23 - NCT06315075Recruiting
Dialectical behavior therapy for teens with self-harm
This trial tests a therapy called dialectical behavior therapy (DBT) for teenagers who have hurt themselves or had suicidal thoughts in the last six months. The goal is to see if DBT helps reduce self-harm and suicidal feelings.
Bergen, BergenAges 13–18 - NCT06314594Recruiting
Personalized care for teens with scoliosis
This study tests a personalized health management plan for teens with mild to moderate scoliosis (spine curve less than 45 degrees). It aims to help prevent the curve from getting worse and improve treatment through a special online platform.
Hangzhou, ZhejiangAges 3–18 - NCT06306586Recruiting
Digital therapy for teens with eating disorders
This trial tests a digital treatment for adolescents aged 15 to 18 with certain eating disorders, like atypical anorexia or bulimia. It's designed to be done online, so you can participate from home.
Bømlo, VestlandAges 15–18 - NCT06262269Recruiting
Home exercise program for teens with scoliosis
This trial tests whether a home-based exercise program delivered through video calls can help teens with idiopathic scoliosis. It aims to improve spine curvature and overall well-being without the need to travel to a clinic.
Villeneuve-d'AscqAges 13–17 - NCT06206161Enrolling by invitation
School-based health screening study
This study tests a school program that asks students about their health habits and offers support. It is designed for high school students who are scheduled for this check-in.
Boston, MassachusettsAges 14–19 - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT06072677Recruiting
Mood and testosterone in young teens
This study looks at how mood changes during puberty in young people aged 11 to 14. It tests whether using a mindfulness app (Healthy Minds) can help teens who have been through stress or feel down.
Chapel Hill, North CarolinaAges 11–14 - NCT05691439Recruiting
Sleep Timing, Mood, and Brain Circuits in Teens With Depression
This study looks at how sleep timing affects brain function related to mood and “pleasure” in teenagers who have depressive symptoms. It may help researchers understand why depression and reduced interest/pleasure can happen, and how sleep patterns might be a key factor.
Eugene, OregonAges 14–18 - NCT03935295RecruitingPhase 4
Dysport with a brace for teens with specific scoliosis curves
This trial studies whether adding Dysport (a botulinum toxin shot) to standard bracing can improve scoliosis in teens. It’s mainly for certain curve patterns and requires careful brace follow-through.
Baltimore, MarylandAges 10–16 - NCT05543083Recruiting
Therapy plus exercise for teens at risk of type 2 diabetes
This trial tests whether a combination of coaching (cognitive-behavioral therapy) and exercise can improve mood and help teens who are at higher risk for type 2 diabetes. It may be especially helpful if you’re dealing with depression symptoms and a family history of type 2 diabetes.
Aurora, ColoradoAges 12–17 - NCT05539794Recruiting
Exercise program for teens newly diagnosed with cancer
This trial tests whether a supervised exercise program is safe and helpful for teenagers who are newly diagnosed with cancer (outside the brain) and have not started treatment yet. It may help improve fitness and daily functioning while cancer care is getting underway.
Villaviciosa de Odón, SpainAges 12–19 - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17 - NCT05437588Recruiting
Blood-based biomarkers for suicide risk in teens with depression
This study looks at tiny blood particles (exosomes) and specific microRNAs to see if they can signal suicide risk and predict treatment outcomes in adolescents. If you qualify, your blood may be used to help researchers find better ways to understand and track suicidality and depression treatment response.
Birmingham, AlabamaAges 10–24 - NCT05329441Recruiting
Testing an anti-depression medicine for threat-related brain changes in teens
This trial studies how fluoxetine or escitalopram (anti-depression medicines) may affect brain systems involved in feeling threatened and staying anxious when you have depression. It also uses brain scanning and blood tests to measure these changes.
Los Angeles, CaliforniaAges 14–21
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Common questions
- Are there clinical trials for adolescence?
- Yes. Clin2 currently lists 932 recruiting adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.