Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05849207RecruitingPhase 1
Cyclophosphamide after transplant for people 65 and older
This early-phase study tests giving cyclophosphamide after a specific type of stem cell transplant (haploidentical) in people age 65 and older. It aims to improve transplant safety and outcomes by adjusting medicine given after the graft is placed.
Los Angeles, CaliforniaAges 65 years+ - NCT05844449Enrolling by invitationPhase 3
Check long-term safety and effectiveness of CF medicines
This Phase 3 study looks at how well and how safely Vanzacaftor/Tezacaftor/Deutivacaftor works over the long term in people with cystic fibrosis who already took the study medicine before. It may help confirm the best long-term plan and spot important safety issues.
Orange, CaliforniaAges 1 year+ - NCT05400707Recruiting
Tracking symptoms and other clues in emergency room visits
This study follows people who come to the emergency department to see what symptoms and other factors can help predict what happens next. It may help improve how emergencies are quickly triaged and managed.
BaselAges 18 years+ - NCT05076617Enrolling by invitationPhase 3
Testing a long-acting rescue seizure medicine for prolonged seizures
This Phase 3 study tests the safety and side effects of Staccato alprazolam for teens and adults (12+) who have certain types of long-lasting seizures. It may help people by offering a specific medicine option aimed at stopping prolonged seizure episodes under close medical study.
Phoenix, ArizonaAges 12 years+ - NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Phoenix, ArizonaAges 12 years+ - NCT01306019RecruitingPhase 1/Phase 2
Gene therapy for children with severe immune deficiency (XSCID)
This trial tests a one-time gene therapy approach to help children with X-linked SCID (a serious inherited immune disorder) make better immune cells. It’s for people who don’t have a fully matched sibling donor and need long-term follow-up after treatment.
Bethesda, MarylandAges 2–50 - NCT01132859Recruiting
Study of how immune cells respond in adults
This study looks at how your body’s immune system reacts in different tissues by collecting and storing samples for research. You might be able to join if you’re an adult and can consent, and if you don’t have certain bleeding risks that could make sample collection unsafe.
Bethesda, MarylandAges 18–120 - NCT07477561Recruiting
Healthy aging program for older adults in Singapore
This trial tests a program to help older adults stay independent and prevent frailty. It is based on the World Health Organization's ICOPE approach and is designed for Singaporeans and permanent residents aged 60 and older.
SingaporeAges 60 years+ - NCT07486661Recruiting
Preventing frailty in people with HIV aged 65-75
This study aims to help people with HIV between the ages of 65 and 75 stay healthy and avoid becoming frail as they age. It tests a program to prevent frailty and see if it works.
BrusselsAges 65–74 - NCT06836167Recruiting
Integrated care for frail older adults
This study tests a program called +AGIL Barcelona that provides integrated care for older adults living at home who show signs of frailty. It aims to help them stay independent and healthy.
BarcelonaAges 65 years+ - NCT07596576Recruiting
Slowing aging through comprehensive health screening and interventions
This study helps healthy older adults understand their biological age—how old your body actually is—and tests personalized interventions to help you age more slowly and stay healthier longer. Researchers will perform detailed health assessments and then guide you through targeted treatments based on your individual aging profile.
Ramat Gan, Tel AvivAges 50 years+ - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT05858034Recruiting
Study of aging and frailty in people with HIV over 50
This study looks at what makes some people with HIV become “pre-frail” or frail as they get older. It uses questionnaires and other checks to understand challenges to healthy aging and may help improve future support and care.
Winston-Salem, North CarolinaAges 50 years+ - NCT06073990Enrolling by invitation
Insomnia help for adults 50 and older
This trial tests a short talk therapy that helps improve sleep without medication. It focuses on older adults who have had trouble sleeping for at least 3 months.
Tainan, TaiwanAges 50 years+ - NCT07766954Enrolling by invitationPhase 1
Exercise program for older adults living at home
This trial tests a gymnastics and multi-exercise program for people aged 60 and older who live at home. The goal is to see if this program improves strength, balance, and overall health.
Salvador, Estado de BahiaAges 60–105 - NCT06621368Recruiting
Resistance training for healthy aging in older women
This study tests if two years of resistance exercise helps older women stay healthy and active. It's for postmenopausal women aged 60+ who are not currently exercising regularly.
Londrina, ParanáAges 60 years+ - NCT07687563Enrolling by invitation
Community program for healthy aging in mind and body
This study looks at how strength, purpose, and personal resilience affect well-being in people 55 and older. Participants in a community learning program will take surveys and simple physical tests twice over a few months.
Taipei, Nursing Building, No.155, Sec.2, Li-Nong Street,Ages 55 years+ - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07442097Recruiting
Safety of a nutritional supplement in healthy older adults
This study tests a nutritional supplement (N-acetyl-L-cysteine and glycine) to see if it is safe and well-tolerated in healthy older adults. It may help if you are looking for ways to support your health as you age.
Pune, MaharashtraAges 60–80 - NCT07440017Recruiting
Aging and memory study: How older adults learn
This study uses brain scans to understand how older adults (65-80) and younger adults (18-30) learn and generalize information. It may help explain memory changes with age.
Milwaukee, WisconsinAges 18–80 - NCT07386730RecruitingPhase 1
Psychedelic therapy study for older adults with low well-being
This study tests if a single dose of psilocybin (a psychedelic) or dextromethorphan (a cough suppressant) can improve well-being in healthy older adults who feel their well-being is below average. It aims to understand how these drugs might help boost mood and life satisfaction.
San Francisco, CaliforniaAges 50–85 - NCT07357662Recruiting
Exercise video games for foot strength and balance in older adults
This study tests how playing fun exercise video games (exergames) can improve foot muscle activity, balance, and ability to move around in older adults who are otherwise healthy.
Tarsus, Mersi̇nAges 65–80 - NCT07315724Recruiting
Block training for brain and hand health in older adults
This trial tests whether a technology-assisted block training program can improve thinking skills, hand coordination, and grip strength in older adults living in the community. It may help keep your mind and hands active as you age.
Yilan, TaiwanAges 65 years+
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,068 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.