Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,067 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05077904RecruitingPhase 3
Staccato alprazolam study for prolonged seizures in teens and adults
This Phase 3 trial tests whether staccato alprazolam can reduce and manage “prolonged seizures” that happen repeatedly in people with epilepsy. It also checks safety—especially breathing and heart-related side effects—while participants continue their usual seizure medicines.
Phoenix, ArizonaAges 12 years+ - NCT07677319Recruiting
Heart surgery after age 75: a study on recovery
This study looks at how well people aged 75 and older recover after emergency heart surgery. It uses a special test to measure frailty and quality of life for one year after surgery.
Bordeaux, FranceAges 75 years+ - NCT06915233RecruitingPhase 3
MACI for ankle cartilage defects in adults
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
Sacramento, CaliforniaAges 17–65 - NCT06807281RecruitingPhase 3
Abrocitinib for children with eczema: long-term study
This study tests the long-term safety and effectiveness of abrocitinib (Cibinqo) for children aged 6 to 12 with moderate to severe eczema that hasn't improved with creams. It may help their skin clear and reduce itching.
Birmingham, AlabamaAges 2–11 - NCT05400707Recruiting
Tracking symptoms and other clues in emergency room visits
This study follows people who come to the emergency department to see what symptoms and other factors can help predict what happens next. It may help improve how emergencies are quickly triaged and managed.
BaselAges 18 years+ - NCT05849207RecruitingPhase 1
Cyclophosphamide after transplant for people 65 and older
This early-phase study tests giving cyclophosphamide after a specific type of stem cell transplant (haploidentical) in people age 65 and older. It aims to improve transplant safety and outcomes by adjusting medicine given after the graft is placed.
Los Angeles, CaliforniaAges 65 years+ - NCT05928767Recruiting
Using frailty scores to predict death in ICU sepsis
This trial checks whether a “frailty” rating (how physically/mentally vulnerable someone is) can predict the risk of death in ICU patients with sepsis shock. It may help doctors identify higher-risk patients earlier and tailor care.
BéthuneAges 18–65 - NCT06247085RecruitingPhase 3
A study testing pegtibatinase for classical homocystinuria
This trial tests an injectable drug called pegtibatinase for people with a rare condition called homocystinuria. It aims to lower high levels of homocysteine in the blood compared to a placebo, while you continue your usual treatments.
Phoenix, ArizonaAges 12–65 - NCT06416618Recruiting
Surgery vs. No Surgery for Shoulder Fracture, Ages 50-65
This trial compares surgery versus non-surgical treatment for a broken shoulder bone (proximal humerus) in adults aged 50 to 65. It aims to find which approach leads to better recovery and function.
Køge, Region SjællandAges 50–65 - NCT06666491RecruitingPhase 3
Comparing two malaria treatments for P. vivax in people 2 and older
This study compares two medicines (tafenoquine and primaquine) taken with chloroquine to treat P. vivax malaria. It aims to see which is safer and works better in Indian participants aged 2 to 64.
AhmedabadAges 2–64 - NCT06717581Recruiting
Drug interaction study for older people with HIV
This study looks at how other medicines you take for conditions like high blood pressure, diabetes, or cholesterol might interact with your HIV medication (Biktarvy) if you are 60 or older. The goal is to learn how to better manage your overall health.
BolognaAges 18 years+ - NCT06874842RecruitingPhase 1
Testing a new shingles vaccine in adults 40 and older
This trial tests a new shingles vaccine (LYB004) in adults 40 and older. It looks at how safe the vaccine is and how well it helps your body build protection against shingles.
MeizhouAges 40 years+ - NCT06891885RecruitingPhase 1/Phase 2
Safety study of DSP-3077 for retinitis pigmentosa
This trial tests a new medicine, DSP-3077, given as a single injection into one eye to see if it is safe for people with retinitis pigmentosa. It is for adults with advanced vision loss who have no other major eye diseases.
Boston, MassachusettsAges 18 years+ - NCT06962696Recruiting
Testing AI to check home safety for older adults
This trial uses a smart computer program (GPT-4o) to check the safety of your home environment and see if it's safe for older adults. It's designed for seniors who live at home and can communicate easily.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06972537Recruiting
Piperacillin-Tazobactam Dosing for Pneumonia in Older Adults
This study looks at the best way to give the antibiotic piperacillin-tazobactam (Zosyn) to people 65 and older who have pneumonia. It aims to make treatment more effective and safer for older adults.
Jinan, ShandongAges 65–100 - NCT06975865RecruitingPhase 3
Rilzabrutinib for sickle-cell disease pain episodes
This study tests an oral medicine called rilzabrutinib to see if it can reduce painful episodes in people with sickle-cell disease. It may be an option if you have regular pain crises and are looking for a new treatment.
Birmingham, AlabamaAges 10–65 - NCT06988176Recruiting
Frailty and muscle strength in older adults having major surgery
This study looks at how frailty and muscle strength affect recovery in adults 65 and older who are having planned major abdominal surgery. The goal is to see if simple tests can help predict outcomes and guide better care.
Chapel Hill, North CarolinaAges 65 years+ - NCT07086976RecruitingPhase 3
Study of oral rilzabrutinib for warm autoimmune hemolytic anemia
This trial tests an oral medication (rilzabrutinib) against a placebo for people with warm autoimmune hemolytic anemia (wAIHA). It aims to see if the drug can help control the disease with fewer side effects than current treatments.
Phoenix, ArizonaAges 18 years+ - NCT07241299Recruiting
Understanding long-term medications in adults 65+
This study looks at how people aged 65 and older understand their long-term medications (treatments taken for more than 3 months). It aims to improve communication between patients and doctors.
Reims, Université de Reims Champagne-ArdenneAges 65 years+ - NCT06241118RecruitingPhase 3
New injection for eczema not helped by other advanced treatments
This study tests a new injection called amlitelimab for teens and adults with moderate-to-severe eczema that hasn't gotten better with other advanced treatments like biologics or JAK inhibitor pills. It's given along with steroid creams to see if it can improve symptoms.
Birmingham, AlabamaAges 12 years+ - NCT07297602RecruitingPhase 2
Oral roflumilast for moderate to severe eczema in teens and adults
This study tests an oral medicine called roflumilast to see if it helps treat moderate to severe eczema in people aged 12 and up who haven't used other systemic treatments recently. It's a pilot study to check both safety and how well it works.
Al Mansurah, Dakahlia GovernorateAges 12 years+ - NCT07265674RecruitingPhase 3
Study of nanvuranlat for advanced bile duct cancer
This study tests a new drug called nanvuranlat for people with advanced bile duct cancer that has gotten worse after platinum-based chemotherapy. It compares nanvuranlat with the doctor's choice of standard treatments to see which works better.
Duarte, CaliforniaAges 18 years+ - NCT07394790Recruiting
Exercise program for adults 65 and older
This study tests if a personalized exercise program prescribed by your doctor can help people 65 and older stay active and healthy. You would meet with a healthcare team to get a simple exercise plan and see how it affects your well-being.
Villoría, SalamancaAges 65 years+ - NCT01306019RecruitingPhase 1/Phase 2
Gene therapy for children with severe immune deficiency (XSCID)
This trial tests a one-time gene therapy approach to help children with X-linked SCID (a serious inherited immune disorder) make better immune cells. It’s for people who don’t have a fully matched sibling donor and need long-term follow-up after treatment.
Bethesda, MarylandAges 2–50
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,067 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.