Clinical trials
Alzheimer’s disease clinical trials
A progressive brain disorder that affects memory and thinking. We’re tracking 595 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06297590RecruitingPhase 1
First human study of a new Alzheimer's drug
This study tests an experimental drug (LY3954068) for people with early Alzheimer's disease. It aims to see if the drug is safe and may slow memory loss. You'll need a PET scan to measure tau protein in the brain and have a study partner who can help attend appointments.
Maitland, FloridaAges 50–85 - NCT06385106Recruiting
Brain stimulation for memory loss in Alzheimer's
This study tests if repetitive transcranial magnetic stimulation (a non-invasive brain stimulation technique) can help improve memory and thinking in people with Alzheimer's disease. It may be an option if you are between 55 and 80, right-handed, and have a confirmed diagnosis of Alzheimer's.
Hangzhou, ZhejiangAges 55–80 - NCT06442852Recruiting
Blood microRNA linked to Alzheimer's risk and severity
This study looks for tiny molecules (miRNAs) in your blood that might be linked to Alzheimer's disease risk and severity. It compares people with Alzheimer's to healthy volunteers to find potential early warning signs.
Wuhan, HubeiAges 65 years+ - NCT06448975Recruiting
Study of neck surgery for Alzheimer's disease
This trial tests a new surgery on neck lymph vessels to see if it helps people with Alzheimer's. It is for patients aged 60 to 80 with mild to severe Alzheimer's who have had the diagnosis for over a year.
Wuxi, JiangsuAges 60–80 - NCT06514001RecruitingPhase 2
Testing a new drug for Alzheimer's disease with eye scans
This trial tests an investigational drug called AMDX-2011P for people with Alzheimer's disease. It looks at whether the drug affects the retina, which may be linked to brain changes in Alzheimer's.
Phoenix, ArizonaAges 18 years+ - NCT06535308RecruitingPhase 1
Testing a new Alzheimer's drug for moderate disease
This study tests a new drug (BnH-015B) for people with moderate Alzheimer's disease. It also includes a small group of healthy young men for comparison. The goal is to see if the drug is safe and how it works in the body.
Seoul, Jongno-guAges 19–45 - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06566170Recruiting
Donanemab for early Alzheimer's: a real-world study
This study compares donanemab plus usual care to usual care alone for people with early Alzheimer's symptoms, to see how well donanemab works in everyday life. You may be able to join if you have early memory or thinking problems and have a brain scan or blood test showing Alzheimer's-related changes.
Huntsville, AlabamaAges 60 years+ - NCT06582706RecruitingPhase 1/Phase 2
Vitamin B3 (niacin) for Alzheimer's disease
This study tests if nicotinic acid (a form of vitamin B3) can help people with mild to moderate Alzheimer's disease. It involves taking a daily pill, having a lumbar puncture, and regular check-ups to see if the vitamin improves thinking and memory.
Indianapolis, IndianaAges 60–85 - NCT06585384RecruitingPhase 1
Safety of etanercept with contrast ultrasound for Alzheimer's
This study tests whether combining a drug called etanercept with repeated contrast ultrasound is safe for people with mild Alzheimer's. It aims to see if this approach can help slow the disease.
ParisAges 50–85 - NCT06611878Recruiting
Music training for Alzheimer's patients at home
This trial tests whether intensive music training can help memory in people with Alzheimer's disease who live at home and are not musicians.
Buenos AiresAges 65 years+ - NCT06678100Recruiting
Swallowing study for adults with Alzheimer's
This study looks at swallowing problems in people with Alzheimer's disease compared to healthy older adults. If you have Alzheimer's, you'll have a swallowing test and your caregiver will answer questions about your daily life.
Nashville, TennesseeAges 60 years+ - NCT06702124RecruitingPhase 3
Rotigotine patch with rivastigmine for mild to moderate Alzheimer's
This trial tests if adding a rotigotine patch to your usual rivastigmine treatment can help with symptoms of Alzheimer's. It is for people with mild to moderate Alzheimer's who have been stable on rivastigmine for at least 3 months.
Rome, ItalyAges 50–85 - NCT06703541Recruiting
Alzheimer's disease research study with brain scans and spinal tap
This study at Duke University is looking for people aged 25 to 80 who may be at risk for Alzheimer's disease. It involves brain scans (MRI and PET) and a spinal tap to learn more about the disease and find better ways to detect and treat it early.
Durham, North CarolinaAges 25–80 - NCT04576793RecruitingPhase 2
Imaging brain inflammation in Alzheimer’s and related variants over time
This Phase 2 study uses repeated brain MRI scans to track “microglial activation,” which is a marker of brain immune/inflammation activity, in different Alzheimer’s-related conditions. It may help researchers understand how brain inflammation changes over time and differs between people with these clinical variants.
New York, New YorkAges 50 years+ - NCT06731049Recruiting
Walking training with and without dual tasks for Alzheimer's
This study compares treadmill walking to walking while doing a second task (like talking or carrying something) in people with Alzheimer's disease. It aims to see which training method improves mobility and safety better.
IstanbulAges 65–85 - NCT06732128Recruiting
Nature virtual reality for depression in Alzheimer's disease
This trial tests whether a virtual reality nature experience can help improve mood in people with early-to-moderate Alzheimer's disease. Participants will use a VR headset and a few apps at home, with a caregiver present, over several sessions.
Toronto, OntarioAges 50 years+ - NCT06781333RecruitingPhase 2
Stem cells for behavior problems in Alzheimer's
This trial tests whether a single infusion of human mesenchymal stem cells (hMSC) can improve difficult behaviors like agitation, anxiety, or hallucinations in people with Alzheimer's disease. It's designed for those who have been taking antipsychotic medication for at least 4 weeks and have a study partner to help track behavior changes.
Miami, FloridaAges 55–90 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT06841848Recruiting
Eye camera test for early Alzheimer's
This study is testing a new eye camera to see if it can help find early signs of Alzheimer's disease. It is for people aged 55 and older who either have mild to moderate Alzheimer's or do not have Alzheimer's.
Rome, ItalyAges 55 years+ - NCT06874231Recruiting
Brain connectivity marker for Alzheimer's disease
This study uses brain scans to find a marker for Alzheimer's disease. It is looking for people with normal memory, mild memory problems, or mild Alzheimer's, and who can undergo a spinal tap and MRI.
Stockholm, SolnaAges 40–85 - NCT06875986Recruiting
Study of REXULTI for agitation in Alzheimer's disease
This trial is studying how a medication called REXULTI works in patients with Alzheimer's disease who have symptoms like excessive activity, aggression, or mood swings. It aims to see if the drug helps manage these behaviors.
Osaka, OsakaAges 15 years+ - NCT06883019Recruiting
Lecanemab for early onset inherited Alzheimer's
This trial tests a medication called lecanemab for people with early onset familial Alzheimer's disease. It aims to see if the drug can help slow cognitive decline in those with confirmed signs of Alzheimer's in their brain.
Beijing, ChinaAges 18–65 - NCT06936124Recruiting
Deep brain stimulation for Alzheimer's disease
This trial tests whether deep brain stimulation of a specific brain area can help people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and quality of life.
Toronto, OntarioAges 60 years+
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Common questions
- Are there clinical trials for alzheimer’s disease?
- Yes. Clin2 currently lists 595 recruiting alzheimer’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.