Clinical trials · Massachusetts
Amputation clinical trials in Massachusetts
We’re tracking 13 recruiting amputation studies with a site in Massachusetts — including Early Phase 1 and Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT06908538Recruiting
Cryo nerve block for pain after amputation
This study is testing a treatment called a cryo nerve block to reduce pain after amputation, including phantom limb pain. It will look at whether freezing the nerve during surgery helps people feel less pain and use less pain medicine.
Pittsfield, MassachusettsAges 18 years+ - NCT07011420Recruiting
Testing different prosthetics controls for arm amputees
This trial tests how different numbers and types of muscle signals (myoelectric) affect control of a prosthetic hand and wrist. It aims to find the best setup for people with a below-elbow amputation who have used a myoelectric prosthetic before.
Holliston, MassachusettsAges 18 years+ - NCT03882073Recruiting
Upper arm amputation rehab study to improve hand control and feel
This trial tests a new approach for rehabilitation after an upper-limb amputation to help improve your ability to intentionally control a prosthetic and regain a sense of position (“proprioception”). You may be considered if you are planning an elective upper-arm or below-elbow amputation and can safely have surgery and follow up closely.
Boston, MassachusettsAges 18–65 - NCT01293214Recruiting
Transplanting new tissue for multiple amputated limbs
This trial studies whether a transplant of tissue and blood vessels can improve function after limb amputations when prosthetic devices have not worked. It requires long-term medicines to prevent rejection, close follow-up, and intensive rehabilitation.
Boston, MassachusettsAges 18–60 - NCT07222085Recruiting
Long-term test of a new myoelectric control strategy
This trial tests a new way to control a powered prosthetic arm called Glide control. Researchers want to see if it stays reliable over time for people who have lost part of their arm below or above the elbow.
Allston, MassachusettsAges 18 years+ - NCT05964855Enrolling by invitation
Test of different prosthetic foot and ankle mechanisms
This study compares different prosthetic foot and ankle designs for people who have an above-ankle (transtibial) amputation. It may help find which designs work best for your mobility level.
Burlington, MassachusettsAges 18–65 - NCT07204912Recruiting
Testing a brain-controlled leg prosthesis in real-world tasks
This trial tests a new powered leg prosthesis that you control with your own neural signals. It aims to help people with above-knee amputations walk more naturally in everyday situations.
Cambridge, MassachusettsAges 18–70 - NCT07195461RecruitingEarly Phase 1
Magnetic beads helping control a robotic leg
This trial tests a new system that uses tiny magnetic beads to help a robotic leg move more naturally. It aims to improve function for people who need a below-knee amputation or already have one that needs fixing.
Boston, MassachusettsAges 22–65 - NCT07645729Recruiting
Testing a Powered Ankle Prosthesis with Neural Control
This study tests a new powered ankle prosthesis (an artificial foot with a motor) that you control using signals from your nerves and receive feedback through gentle stimulation on your skin. The goal is to see if it helps you walk more naturally and perform daily activities with better balance and control.
Cambridge, MassachusettsAges 18–70 - NCT04063592Recruiting
Surgery plan for pain or skin problems in a healed leg stump
This study looks at a surgical approach for people who already had an above-knee or below-knee amputation and now have ongoing pain or skin/stump problems that haven’t improved. It aims to improve comfort and how well the stump area heals, assuming you’re healthy enough for surgery under standard anesthesia.
Boston, MassachusettsAges 18–65 - NCT05009394Recruiting
Surgery options for long-term pain after limb amputation
This trial studies different surgical approaches to reduce persistent pain in the leftover part of an amputated limb. You may be able to join if your post-amputation pain has lasted more than a year and your pain level stays high despite stable pain treatments and prosthesis use.
Boston, MassachusettsAges 18 years+ - NCT06915662RecruitingPhase 2
A nerve cap for pain after finger amputation
This trial tests a small nerve cap, called Tulavi Allay, placed on the end of a cut nerve during finger amputation surgery. The cap is meant to reduce pain and protect the nerve ending. It is for people who have lost one or more fingers in an accident.
Boston, MassachusettsAges 22 years+ - NCT07613840Recruiting
Personalized Blood Clot Prevention After Leg Artery Surgery
This study tests a personalized approach to prevent blood clots in patients who have had surgery to repair blocked arteries in their legs. Researchers want to find the best blood-thinning medication for each individual to reduce serious complications while keeping you safe.
Salem, MassachusettsAges 18 years+
Amputation trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting amputation studies listed above.
- Massachusetts Institute of Technology · 5 studies
- Brigham and Women's Hospital · 4 studies
- Massachusetts General Hospital · 4 studies
- A Step Ahead Prosthetics
- Berkshire Medical Center
- Liberating Technologies, Inc.
- Medical Center Orthotics and Prosthetics - Allston
- Medical Center Orthotics and Prosthetics - Milton
What taking part in a amputation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Amputation trials in other states
Common questions
- Are there amputation clinical trials in Massachusetts?
- Yes. We're currently tracking 13 recruiting amputation studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a amputation study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a amputation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New amputation studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.