Clinical trials · Philadelphia, PA
Amyotrophic Lateral Sclerosis clinical trials in Philadelphia
We’re tracking 11 recruiting amyotrophic lateral sclerosis studies with a site in or near Philadelphia — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Philadelphia
- NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07161999RecruitingPhase 2/Phase 3
COYA 302 treatment for ALS
This study tests an experimental treatment called COYA 302 for ALS. It aims to see if it can slow down the worsening of muscle weakness and improve daily function. It might be an option for people in the earlier stages of ALS.
Philadelphia, PennsylvaniaAges 18–80 - NCT06578195Recruiting
Assess all ALS study
This study follows people with ALS and healthy volunteers over time to understand the disease better. You can join from home using a smartphone or computer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06581861Recruiting
Family study to prevent ALS and FTD
This study is for adults who have a strong family history of ALS or FTD (like a parent or sibling with the disease) to help researchers understand how to prevent these conditions. It involves following you for about a year to track your health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07322003RecruitingPhase 3
Pridopidine for ALS: Phase 3 trial testing safety and effectiveness
This trial is testing if an oral medication called pridopidine can slow the progression of ALS. It is for people recently diagnosed with ALS who have mild to moderate breathing function and meet specific risk scores.
Philadelphia, PennsylvaniaAges 18–80 - NCT07287397RecruitingPhase 1/Phase 2
Testing VTx-002 for safety in ALS patients
This trial tests a new drug called VTx-002 to see if it is safe and tolerable for people with ALS. You may be able to join if you have had symptoms for less than 18 months and have a caregiver who can help.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07290062RecruitingPhase 1
Gene therapy injection for ALS safety study
This trial tests a single injection of a gene therapy called INS1202 into the spinal fluid. It is for people with ALS, including those with a specific genetic form (SOD1 mutation). The goal is to see if it is safe and how it affects the body.
Philadelphia, PennsylvaniaAges 18–79 - NCT06665165RecruitingPhase 1
Study of AMX0114 for people with ALS
This study tests an experimental drug called AMX0114 for people recently diagnosed with ALS. It is an early-phase trial to see if the drug is safe and how it affects the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07703462Enrolling by invitationPhase 1/Phase 2
Personalized therapy for TARDBP ALS
This trial offers a custom-made treatment for people with ALS caused by a TARDBP gene mutation. It uses a personalized medicine approach to target the specific genetic cause of the disease.
Philadelphia, PennsylvaniaAges Any age
Hear when a new Amyotrophic Lateral Sclerosis trial opens near Philadelphia, PA
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Amyotrophic Lateral Sclerosis trials in other cities
Where these studies are running near Philadelphia
Institutions with a site for the recruiting amyotrophic lateral sclerosis studies listed above.
- Temple University Hospital · 4 studies
- University of Pennsylvania · 4 studies
- Thomas Jefferson University Hospital · 2 studies
- Fox Chase Cancer Center
- Pennsylvania Hospital
- USA006
What taking part in a amyotrophic lateral sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting amyotrophic lateral sclerosis studies in Pennsylvania.
Common questions
- Are there amyotrophic lateral sclerosis clinical trials near Philadelphia?
- Yes. We're currently tracking 11 recruiting amyotrophic lateral sclerosis studies with a site near Philadelphia, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a amyotrophic lateral sclerosis study near Philadelphia?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Philadelphia to take part?
- Not necessarily. These studies have a site near Philadelphia, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New amyotrophic lateral sclerosis studies open near Philadelphia regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.