Study of frontotemporal dementia and related syndromes over time
Part of Brain & nervous system, Eyes & vision, Hormones & metabolism, Mental health clinical trials.
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have an FTLD-related diagnosis: PSP, svPPA, nfvPPA, CBD/CBS, bvFTD, or FTD/ALS
- Or you’re in a family where someone has a known mutation linked to FTLD (MAPT, GRN, C9orf72), or there’s a clear inherited pattern in the family
- You do not have a brain problem like a tumor or stroke that could explain your symptoms
- You don’t have an Alzheimer's disease cause (such as PSEN1, PSEN2, APP mutation) or clear evidence that Alzheimer’s is the cause
- You don’t have certain other health issues that can mimic dementia (like untreated B12 deficiency, severe thyroid problems, HIV, major kidney or liver failure, or major lung/respiratory failure)
- You must be able to complete required study visits and tests (or, for the biofluid option, at least a blood draw and short exam)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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