Clinical trials
Anesthesia, Local clinical trials
Below are recruiting anesthesia, local clinical trials, each written for real people, not researchers. We’re tracking 68 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06416657Recruiting
General vs local anesthesia for brain aneurysm treatment
This trial compares general anesthesia (being fully asleep) to local anesthesia (only the area is numbed) during a procedure to treat an unruptured brain aneurysm with a flow diverter. It aims to find which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–80 - NCT06642649Recruiting
Comparing anesthesia types to reduce opioids in hysterectomy
This study compares general anesthesia alone to two types of combined anesthesia (general plus spinal) to see which reduces the amount of opioid painkillers needed during and after a laparoscopic hysterectomy. It may help patients recover with less reliance on strong pain medications.
Bellinzona, SwitzerlandAges 18 years+ - NCT07074730Recruiting
Anesthesia types for urethral surgery
This trial compares general anesthesia versus spinal anesthesia with local numbing medicine for penis skin graft surgery. It aims to see which method works better for pain control and recovery.
Tanta, El-GharbiaAges 21 years+ - NCT05841290Recruiting
Compare types of dental sealers for post-procedure pain
This study checks how much pain happens after dental procedures using different types of filling/sealing materials. It may help you and future patients understand which sealer options tend to cause less postoperative discomfort.
El Shorouk, Cairo GovernorateAges 18–50 - NCT07449884Recruiting
AI avatar vs. tell-show-do for children's dental anxiety
This trial compares using an AI avatar video with the traditional tell-show-do method to help children aged 5 to 7 feel less anxious and cooperate better during a numbing injection at the dentist. It may benefit children who have never had dental anesthesia before and are generally healthy.
BeirutAges 5–7 - NCT07408414Recruiting
Pain relief after laser pilonidal sinus treatment
This trial studies which local numbing method works best to reduce pain after laser treatment for pilonidal sinus. It may help people with this condition feel more comfortable after their procedure.
PožegaAges 18 years+ - NCT04849455RecruitingPhase 4
Nerve-block catheters plus spinal morphine for liver surgery pain
This trial tests whether placing pain-relief catheters near the back muscle plus giving morphine into the spinal fluid can improve comfort during and after liver surgery. It may help reduce the need for stronger opioid pain medicines afterward.
San Diego, CaliforniaAges 18 years+ - NCT07239817Recruiting
Nerve block plus numbing medicine for hip fracture surgery
This study tests a special nerve block (PENG block) combined with a numbing medicine injection around the hip joint to provide better pain relief after hip replacement surgery for a broken hip. It aims to see if this approach can reduce pain and the need for strong pain medicines.
MilanAges 18 years+ - NCT06657872Recruiting
Local anesthesia for Rezum treatment of enlarged prostate
This trial tests if a special catheter that numbs the prostate (Schelin catheter) works better than standard local anesthesia during Rezum, a steam treatment for enlarged prostate. It aims to make the procedure less painful for men with bothersome urinary symptoms.
MarseilleAges 18–80 - NCT05964387Recruiting
Silver fluoride treatment and local numbing for tooth cavities
This study tests whether applying silver diamine fluoride (a cavity-stopping liquid) changes how well local numbing works during dental treatment for certain tooth defects. It may help determine the safest and most comfortable way to treat weak, cavity-prone molars in children.
Ann Arbor, MichiganAges 6–11 - NCT05819801Recruiting
Testing how fasting affects outcomes in certain hand procedures
This study looks at whether fasting before a specific hand surgery done with local numbing medicine (and without a tourniquet) changes patient outcomes. It may help explain how to prepare for this type of procedure and what fasting rules are safest.
Orange, CaliforniaAges 18 years+ - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT06417060Recruiting
Comparing pain relief methods for hypospadias surgery
This trial tests two ways to manage pain during and after surgery to fix hypospadias (a condition where the urinary opening is not at the tip of the penis). One method uses a shot of numbing medicine near the tailbone (caudal block) and the other uses local numbing medicine at the surgical site. The study helps find which approach works better for young children.
SkopjeAges 6 months–4 years - NCT07524569Recruiting
Digital vs. manual anesthesia in children's dental care
This study compares two ways of numbing teeth (digital intraosseous and manual intraligamentary anesthesia) in children who need fillings on back molars. It aims to see which method works better and causes less discomfort.
Izmir, CigliAges 6–12 - NCT05951764Recruiting
Checking risk prediction for heart and brain conditions
This study builds or tests computer models that predict risk for heart (cardiovascular) and thinking/memory (neurocognitive) problems using information from people in the general population. It may help improve early detection and planning for care.
ParisAges 45 years+ - NCT06473922Recruiting
Fear and healing after wisdom tooth or jaw implant surgery
This study measures fear and anxiety levels and monitors wound healing in patients getting wisdom tooth extraction or jaw implants, comparing local anesthesia to general anesthesia.
Be’er Ya‘aqovAges 18–85 - NCT06520150Recruiting
Comparing two numbing methods for S-ICD heart device placement
This study compares two ways of numbing the chest area (regional anesthesia) for people getting an S-ICD heart device. The goal is to find which method works better and is safer for patients who are at higher risk for general anesthesia.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT02975310Recruiting
In-clinic endoscopy surgery for chronic sinus polyps
This trial tests an in-clinic (not hospital) endoscopic procedure to remove nasal polyps in people with chronic sinus inflammation, after usual medicines haven’t helped. It may help reduce nasal blockage and improve sinus symptoms, while comparing safety and outcomes after the procedure.
Vancouver, British ColumbiaAges 18 years+ - NCT03696199RecruitingPhase 4
Test better pain control after ankle fracture surgery
This trial studies a pain-control approach (a kind of nerve block) to see if it can reduce pain after surgery for certain ankle fractures. It may help you feel more comfortable while your ankle heals after an operation.
Burlington, MassachusettsAges 18–89 - NCT06694714RecruitingPhase 4
Testing how long numbing medicine lasts on the nose
This study tests two different numbing medicines on the sides of the nose to see how long each lasts and which works better.
New York, New YorkAges 18 years+ - NCT04708171Recruiting
Compare awake, asleep, or no mapping during brain tumor surgery
This study looks at whether surgeons get better safety and control during glioblastoma removal by using awake testing, asleep testing, or no mapping. Mapping helps identify brain areas involved in movement, speech, or vision to lower the risk of serious side effects.
San Francisco, CaliforniaAges 18–90 - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT07601750Enrolling by invitationPhase 4
Local Anesthetic Study for Skin Cancer Surgery
This study tests local anesthetics (numbing medicines) used during Mohs micrographic surgery, a specialized procedure for skin cancer. Researchers want to understand how well these numbing agents work and improve patient comfort during the procedure.
Dallas, TexasAges 18–89 - NCT06528288Recruiting
Numbing injection for pain relief after back fusion surgery
This study tests whether a special numbing injection (called an erector spinae plane block) given near the spine during surgery can reduce pain after lumbar fusion. If you qualify, you might have less pain and need fewer painkillers after your operation.
Worcester, MassachusettsAges 18 years+
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Anesthesia, Local trials by city
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Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for anesthesia, local?
- Yes. Clin2 currently lists 68 recruiting anesthesia, local studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anesthesia, local trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anesthesia, local trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.