Clinical trials
Anesthesia, Local clinical trials
Below are recruiting anesthesia, local clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06746168Recruiting
Better pain control after knee replacement surgery
This study tests a new way to manage pain after total knee replacement. It aims to see if a specific local pain block can reduce the need for strong opioids and improve recovery.
Hasselt, LimburgAges 18–85 - NCT07108439Recruiting
Numbing technique for tooth removal in children under anesthesia
This study tests a special numbing technique (intraosseous anesthesia) for removing permanent back teeth in children who are already under general anesthesia for dental treatments. The goal is to see if it helps reduce pain after the procedure.
GhentAges 6–12 - NCT05271331Recruiting
Numbing injection options for back surgery pain
This trial compares two ways of numbing tissue during a planned back surgery called a laminectomy: an “ESPB block” versus numbing the wound directly. It aims to see which method works better for pain control and comfort after surgery.
Padova, VenetoAges 18 years+ - NCT07337772Recruiting
Comparing corticosteroid doses in knee replacement pain relief injection
This study compares different doses of a corticosteroid (an anti-inflammatory medicine) injected into the knee during total knee replacement surgery. The goal is to see which dose provides the best pain relief after surgery. It is for people having their first knee replacement due to osteoarthritis.
Fuzhou, FujianAges 18–100 - NCT06946498Recruiting
Local anesthesia thoracoscopy for diagnosing unknown fluid around the lung
This study tests a newer, less invasive procedure to diagnose the cause of fluid buildup around the lung. It uses local anesthesia and a small camera to look inside the chest, which may make diagnosis faster and more comfortable.
Athens, AtticaAges 18–90 - NCT06691269Recruiting
Light therapy for pain-free dental care in kids
This study tests a special light therapy called photobiomodulation to see if it can reduce pain during routine dental care in children. It may offer a safe, non-drug way to help kids feel more comfortable at the dentist.
Baltimore, MarylandAges 6–12 - NCT05473858RecruitingPhase 3
Compare sedation dentist injections with laser treatment for children
This trial compares two ways of giving dental pain control for children who need a specific injection near a back lower tooth. It aims to see which approach works better and is more comfortable for kids during treatment under anesthesia.
CairoAges 6–10 - NCT06406010RecruitingPhase 4
Nerve block for pain after hip surgery
This trial tests whether a specific nerve block can reduce pain after a hip socket surgery. The results could help improve recovery and reduce the need for strong painkillers.
CopenhagenAges 18 years+ - NCT07429812Enrolling by invitation
Chitosan-Chlorhexidine Gel for Healing After Tooth Extraction
This trial tests a gel made from chitosan and chlorhexidine to see if it helps heal wounds faster after tooth removal in people with diabetes.
Al KharjAges 20–50 - NCT06910241RecruitingPhase 3
Lidocaine vs. Diphenhydramine for Stitches in ER
This trial compares two numbing medicines—lidocaine and diphenhydramine—to see which works better for stitching up cuts in the emergency room. It helps find the fastest, most comfortable option for people needing stitches.
Boynton Beach, FloridaAges 18 years+ - NCT06725134Recruiting
Do therapy dogs help kids feel calmer during dental shots?
This study tests if having a trained therapy dog in the room reduces a child's anxiety and improves their behavior when getting numbing medicine for dental work. It could help children who are nervous about dental procedures feel more at ease.
Ann Arbor, MichiganAges 4–12 - NCT07017400Recruiting
Nerve block for knee replacement pain relief
This trial tests a nerve block called the sacral erector spinae plane block to see if it improves pain control after total knee replacement surgery. If you're having a knee replacement and staying in the hospital overnight, you may be able to join.
CrotoneAges 18 years+ - NCT07217626RecruitingPhase 4
Nerve blocks before leg fracture surgery in older adults
This trial tests whether giving a nerve block (medicine to numb the leg) before surgery helps older adults recover better from a broken leg bone. If you are 50 or older and need surgery for a specific type of leg fracture, you may be eligible.
Baltimore, MarylandAges 50 years+ - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT04109365Recruiting
Study of epidural placement technique during labor
This trial studies an approach to placing an epidural (pain medicine placed near the spine) during early labor. It aims to improve how safely and accurately epidurals are positioned, which may help with comfort during childbirth.
Palo Alto, CaliforniaAges 18 years+ - NCT04708808Recruiting
Music therapy during ultrasound-guided abortion procedure
This trial tests whether listening to music during an ultrasound-guided vacuum aspiration procedure can help make the procedure more comfortable or less stressful. It focuses on people having first-trimester pregnancy termination under local anesthesia.
Hong Kong, ShatinAges 18 years+ - NCT05448807RecruitingPhase 3
Phentolamine to reverse numbing from dental local anesthesia in kids
This trial studies whether phentolamine can quickly undo (reverse) the numbness from local anesthesia used during dental procedures in children. It may help kids feel normally sooner and safely use their mouth (like speaking and drinking) after treatment.
Cairo, El ManialAges 5–7 - NCT06284473RecruitingPhase 4
Ketamine with numbing medicine for minor emergency procedures
This study tests whether adding ketamine to the usual numbing medicine makes minor procedures in the emergency department less painful. You may be a good fit if you are having a small procedure like stitches or abscess drainage.
Maywood, IllinoisAges 7–70 - NCT06346132Recruiting
Does virtual reality help during heart device surgery?
This study tests if wearing a virtual reality headset during a heart device implant or battery change helps you feel more comfortable and relaxed. The surgery is done under local anesthesia (numbing medicine) while you stay awake, and you go home the same day.
Lugano, Canton TicinoAges 18 years+ - NCT06426992Recruiting
Microwave ablation for small liver tumors
This study tests a microwave ablation device to destroy small liver tumors (up to 4 cm) using heat, without major surgery. It is designed for patients with limited disease (1 or 2 tumors) and good liver function.
SeoulAges 20–85 - NCT06429501RecruitingPhase 2
Numbing medicine for facial fracture surgery
This study tests numbing medicine (local anesthetic) given during surgery for broken facial bones, like the jaw or cheekbones. The goal is to see how well it works and if it helps recovery.
St Louis, MissouriAges 18 years+ - NCT06564987RecruitingPhase 1
Risk of nerve damage from numbing shots for dental work
This study looks at whether a common numbing shot for dental procedures can cause nerve damage. It may help dentists choose safer ways to numb your teeth.
Akron, OhioAges 18–55 - NCT06576128Recruiting
Numbing injection for pain relief during heart procedures
This study tests whether an ultrasound-guided numbing injection in the belly wall can reduce pain during heart procedures like angioplasty or stent placement. It is for people having planned (non-emergency) heart catheterization.
IstanbulAges 18 years+ - NCT06731998Recruiting
Improving pain control after cancer surgery
This study compares different methods of managing pain after minimally invasive surgery for abdominal cancers. It aims to find which approach works best to reduce pain and improve recovery.
Pittsburgh, PennsylvaniaAges 18–89
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Common questions
- Are there clinical trials for anesthesia, local?
- Yes. Clin2 currently lists 67 recruiting anesthesia, local studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anesthesia, local trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anesthesia, local trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.