Clinical trials
Anesthesia, Local clinical trials
Below are recruiting anesthesia, local clinical trials, each written for real people, not researchers. We’re tracking 67 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05271331Recruiting
Numbing injection options for back surgery pain
This trial compares two ways of numbing tissue during a planned back surgery called a laminectomy: an “ESPB block” versus numbing the wound directly. It aims to see which method works better for pain control and comfort after surgery.
Padova, VenetoAges 18 years+ - NCT07337772Recruiting
Comparing corticosteroid doses in knee replacement pain relief injection
This study compares different doses of a corticosteroid (an anti-inflammatory medicine) injected into the knee during total knee replacement surgery. The goal is to see which dose provides the best pain relief after surgery. It is for people having their first knee replacement due to osteoarthritis.
Fuzhou, FujianAges 18–100 - NCT07810452Recruiting
Numbing methods for baby tooth nerve treatment
This study tests different numbing methods to stop bleeding during a dental procedure (pulpotomy) on baby molars. It aims to find the most effective technique to improve comfort and outcomes for children.
Afyonkarahisar, AfyonkarahisarAges 6–9 - NCT06946498Recruiting
Local anesthesia thoracoscopy for diagnosing unknown fluid around the lung
This study tests a newer, less invasive procedure to diagnose the cause of fluid buildup around the lung. It uses local anesthesia and a small camera to look inside the chest, which may make diagnosis faster and more comfortable.
Athens, AtticaAges 18–90 - NCT07794527Recruiting
Nerve blocks to improve recovery after heart bypass surgery
This study tests whether giving multiple nerve blocks (numbing injections near nerves) during off-pump heart bypass surgery can improve your recovery and pain control. It aims to see if these blocks help you feel better and recover faster after surgery.
CairoAges 18–65 - NCT07718477Recruiting
Comparing child and parent pain during dental numbing
This study compares the pain a child feels during a numbing injection at the dentist to the pain the parent thinks the child is feeling. It helps doctors understand the difference between a child's actual pain and what parents perceive, which may improve how pain is managed during dental visits.
Clermont-FerrandAges 6–15 - NCT07638254Recruiting
Buffered vs. Standard Numbing for Dental Pain in Children
This study tests whether a specially prepared numbing medicine works better than standard numbing to reduce pain and anxiety during a dental procedure for children with a painful infected tooth. The goal is to find the gentlest way to numb the area before treatment.
San Luis Potosí City, San Luis PotosíAges 6–12 - NCT07628660Recruiting
Sexual Function After Endometrial Sampling Procedure
This study asks women about their sexual function one month after a routine gynecologic procedure called endometrial sampling (a biopsy of the uterine lining). Researchers want to understand how this procedure affects sexual health when done with sedation or local numbing.
IstanbulAges 18–60 - NCT07518953Recruiting
Can Music Help With Pain During a Nail Biopsy?
This study tests whether listening to music during a nail biopsy—a small procedure to remove a sample of nail tissue—can reduce pain and anxiety. You would listen to music during the procedure and answer a few questions about how you felt.
New York, New YorkAges 18 years+ - NCT07499752Enrolling by invitation
Study on fewer tears: Local anesthesia for first vaginal birth
This study tests whether using local anesthesia during your first vaginal birth can reduce the risk of perineal tears. It aims to make childbirth safer and more comfortable.
StockholmAges 18–64 - NCT07429812Enrolling by invitation
Chitosan-Chlorhexidine Gel for Healing After Tooth Extraction
This trial tests a gel made from chitosan and chlorhexidine to see if it helps heal wounds faster after tooth removal in people with diabetes.
Al KharjAges 20–50 - NCT07371442Enrolling by invitation
Audio distraction and acupoint stimulation for kids during tooth extraction
This study tests two non-drug methods to help children feel less pain and worry during a tooth extraction: an audio-video distraction (like a movie or music) and a special pressure point (acupoint) stimulation on the hand. It aims to see which approach works best for kids ages 5 to 8 who need a baby tooth removed.
Al MansurahAges 5–8 - NCT07217626RecruitingPhase 4
Nerve blocks before leg fracture surgery in older adults
This trial tests whether giving a nerve block (medicine to numb the leg) before surgery helps older adults recover better from a broken leg bone. If you are 50 or older and need surgery for a specific type of leg fracture, you may be eligible.
Baltimore, MarylandAges 50 years+ - NCT07181434Recruiting
Virtual reality for pain relief during leg artery repair
This trial tests whether using a virtual reality headset during a leg artery repair procedure can reduce pain. If you have peripheral artery disease and are having a minimally invasive leg artery surgery under local anesthesia with sedation, you may be able to participate.
PoitiersAges 18 years+ - NCT04109365Recruiting
Study of epidural placement technique during labor
This trial studies an approach to placing an epidural (pain medicine placed near the spine) during early labor. It aims to improve how safely and accurately epidurals are positioned, which may help with comfort during childbirth.
Palo Alto, CaliforniaAges 18 years+ - NCT07130760Recruiting
Testing two numbing methods for tooth pain in a back molar
This trial compares two ways to numb a painful lower back molar. If you have a tooth infection that needs a root canal, you may receive one of two injection techniques to see which works better.
Ferrol, A coruñaAges 18 years+ - NCT07133919Recruiting
AI communication to reduce dental anxiety in children
This trial tests whether a child-friendly, AI-assisted conversation method can help reduce anxiety in children who need a dental filling, pulpotomy, or similar treatment. It is for children ages 6-12 who are coming to the dentist for the first time and will receive local anesthesia.
Çanakkale, KepezAges 7–12 - NCT07060170Recruiting
Can VR or AR glasses help kids feel less pain at the dentist?
This study tests if wearing fun glasses that show virtual or augmented reality can help children feel less pain and worry when getting a numbing shot for a cavity. It compares two types of high-tech glasses to see which works better.
Cairo, EgyptAges 5–8 - NCT07017400Recruiting
Nerve block for knee replacement pain relief
This trial tests a nerve block called the sacral erector spinae plane block to see if it improves pain control after total knee replacement surgery. If you're having a knee replacement and staying in the hospital overnight, you may be able to join.
CrotoneAges 18 years+ - NCT06986083RecruitingPhase 3
Testing changes in prostate biopsy and ablation care
This study looks at two ways to improve prostate procedures: 1) whether adding local anesthesia during a biopsy (while you’re already sedated) makes a difference, and 2) whether a standard care plan before and after focal gland ablation helps recovery compared to usual care.
Basking Ridge, New JerseyAges 18 years+ - NCT06960317Recruiting
Numbing injection for IUD placement pain
This study tests whether a numbing injection (lidocaine) in the cervix can reduce pain during IUD placement. It's for women who have never had a vaginal birth and are getting their first IUD.
La Jolla, CaliforniaAges 18–50 - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT06948162Recruiting
Dental MRI for routine dental care
This study tests whether a special MRI machine can take detailed images of teeth and jaws for routine dental care. It may help find problems without using X-rays.
Minneapolis, MinnesotaAges 18 years+ - NCT06910241RecruitingPhase 3
Lidocaine vs. Diphenhydramine for Stitches in ER
This trial compares two numbing medicines—lidocaine and diphenhydramine—to see which works better for stitching up cuts in the emergency room. It helps find the fastest, most comfortable option for people needing stitches.
Boynton Beach, FloridaAges 18 years+
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Common questions
- Are there clinical trials for anesthesia, local?
- Yes. Clin2 currently lists 67 recruiting anesthesia, local studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anesthesia, local trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anesthesia, local trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.