Clinical trials
Anxiety clinical trials
Ongoing, excessive worry or fear that interferes with daily life. We’re tracking 1,011 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05837104RecruitingPhase 2
Magnesium and vitamin B6 for early bipolar depression
This Phase 2 trial tests whether magnesium plus vitamin B6 can reduce depressive symptoms in people who are newly diagnosed with bipolar I disorder. It also checks for safety over a short, 4-week treatment period.
Belmont, MassachusettsAges 18–50 - NCT05836090Recruiting
Family Spirit Strengths program for pregnant people and caregivers
This trial tests a family-focused program to support mental health and reduce risks related to substance use. It may help you if you’re pregnant or caring for a child 24 months or younger and you’re experiencing depression/anxiety and/or substance-use risk.
Chinle, ArizonaAges 14 years+ - NCT05818696Recruiting
Study for safer firearm storage with uncertainty support
This study looks at how people think and feel about “not knowing” (uncertainty) and how that may affect keeping firearms securely stored. You may be asked to use a phone app and complete short check-ins to support safer storage decisions.
Columbus, OhioAges 18 years+ - NCT05826860Recruiting
Mindfulness and storytelling for graduate student well-being
This study tests whether a mindfulness and storytelling program can improve well-being for graduate students. It is meant for people who are new to mindfulness and want support during graduate school.
Madison, WisconsinAges 18 years+ - NCT05833555Recruiting
Harlem Strong mental health support for adults
This program is for Black and Latino adults in Harlem who are dealing with mild to moderate depression symptoms. It aims to identify people who may benefit from mental health support and connect them with the right level of care.
New York, New YorkAges 18–65 - NCT05800925Recruiting
Triage survey to check who can join psychiatry research
This study uses a short questionnaire to figure out who is eligible to join future psychiatry research. It may help people get routed into studies that match their situation and safety needs.
Boston, MassachusettsAges 18 years+ - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05806112Enrolling by invitation
Improve staff well-being programs for residential care workers
This trial tests whether specific programs can reduce burnout and improve resiliency (coping strength) among staff who work in behavioral health group homes. It may help workers feel better and handle stressful work days.
Boston, MassachusettsAges 18 years+ - NCT05809115Recruiting
Caregiver-child bonding support for hospitalized young children
This study looks at how a caregiver and their young child bond during a hospital stay, and whether extra support can help. It may help families feel more connected and supported while their child is in the hospital.
Houston, TexasAges 18 years+ - NCT05810259Recruiting
Digital wellness modules to improve quality of life
This study tests whether online “wellness” lessons help people feel better in everyday life and report a higher quality of life. It likely involves completing digital wellness modules and answering questionnaires to measure changes over time.
New Haven, ConnecticutAges 18–65 - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT05774002Recruiting
Psychological check-in for teens getting back surgery for scoliosis
This study asks teens with idiopathic scoliosis to complete psychological assessments while planning for elective back surgery. It may help doctors better understand patients’ mental and emotional needs around surgery.
The Bronx, New YorkAges 10–19 - NCT05765656Recruiting
Doctors and pharmacists helping older adults reduce sleeping pills
This study will see if working closely with your doctor and pharmacist can help older adults safely reduce or stop taking medications for anxiety or sleep, like benzodiazepines.
NantesAges 65 years+ - NCT05746767Enrolling by invitation
Spanish digital therapy coaching for depression and anxiety
This study tests a digital “cognitive behavioral therapy” program with peer support to help Spanish-speaking adults with depression or anxiety. It may help you manage symptoms using structured online tools and guided peer interaction.
Payson, ArizonaAges 18 years+ - NCT05712057Recruiting
Brain stimulation vs therapy for emotion regulation problems
This trial compares a type of brain stimulation (rTMS) to therapy to help people better manage strong emotions. You may be eligible if you have ongoing difficulties with emotion control and meet specific mood, anxiety, or related symptom criteria.
Durham, North CarolinaAges 18–55 - NCT05685368RecruitingPhase 1/Phase 2
Therapy groups to help teens cope with sickle cell
This trial tests a structured talk-therapy program called Acceptance and Commitment Therapy (ACT) for teens and young adults with sickle cell disease. It aims to help you manage tough thoughts and feelings and cope with day-to-day challenges over 6 weekly group sessions.
Los Angeles, CaliforniaAges 14–21 - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT05649059RecruitingPhase 4
Cannabidiol study for social anxiety symptoms
This trial studies whether cannabidiol (CBD) helps improve social anxiety symptoms. You may be able to join if you are an adult with significant social anxiety and meet medication and health safety requirements.
Cambridge, MassachusettsAges 18–55 - NCT05603000Recruiting
Emotion-focused therapy for parents of anxious or struggling children
This study tests an emotion-focused family therapy program for parents of children (ages 7–15) who are dealing with anxiety, depression, or behavior challenges. It may help families improve how emotions are understood and managed through parent participation and home life support.
Guelph, OntarioAges 7–15 - NCT05591937Recruiting
Online therapy and prevention support for eligible East LA students
This project offers online mental health prevention and therapy programs and short assessments for eligible students. It may help you access support in a convenient way if you meet the study’s student, coverage, and technology needs.
Los Angeles, CaliforniaAges 18–40
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Common questions
- Are there clinical trials for anxiety?
- Yes. Clin2 currently lists 1,011 recruiting anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.