Artery Stenosis clinical trials

Stent vs. medication for narrowed kidney artery

This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.

New drug-coated stent for thigh artery disease

This study tests a new drug-coated stent to improve blood flow in the thigh artery for people with leg pain or discomfort from narrowed arteries. It aims to see if the stent is safe and works well.

Carotid artery opening study for brain health

This study tests if opening a narrowed carotid artery can reduce brain damage from small vessel disease. It may help patients with carotid artery narrowing prevent cognitive decline.

Ultrasound screening and treatment for artery disease

This study tests if using ultrasound to screen for blocked neck and head arteries can improve treatment plans for people getting heart artery stents. It aims to find hidden blockages and tailor therapy to reduce stroke and other risks.

Photon-Counting CT Versus Conventional CT for Carotid Plaque Assessment in Patients With Carotid Artery Stenosis

Comparing two treatments for narrowed neck arteries

This trial tests whether adding a PCSK9 inhibitor to a statin is better than a statin alone for people with mild-to-moderate narrowing of the carotid artery (the main artery in the neck). It looks at how well these treatments slow plaque buildup and prevent strokes.

Study of treatment planning after carotid artery narrowing

This study looks at an approach to better plan treatment for people with significant narrowing of the carotid artery (the main artery to the brain). It may help doctors choose safer, more effective care after surgery.

Stent or procedure for narrowed carotid artery after neck radiation

This trial studies a carotid artery procedure (revascularization) to treat a major narrowing in the neck artery that happened after you had radiation for head or neck cancer. It may help prevent stroke risk by improving blood flow to the brain.

Drug-coated stent for narrowed vertebral arteries

This trial studies whether a drug-coated stent placed in a narrowed vertebral artery can improve outcomes for people with artery narrowing from plaque. It also looks at how safe the stent is, since it requires specific blood-thinning medicines around the procedure.

Testing a paclitaxel-coated balloon for leg artery disease

This trial tests a special balloon coated with a drug (paclitaxel) to open blocked leg arteries, aiming to improve blood flow and reduce symptoms like leg pain when walking. It is for people with moderate to severe leg artery disease who have not had prior stents or bypass in the treated area.

Stent study for asymptomatic carotid artery blockage

This trial tests a stent procedure to open a severely blocked carotid artery in people who have not had a stroke or mini-stroke from that blockage recently. It aims to see if the procedure is safe and effective for preventing future strokes.

Testing add-on treatment to calm artery inflammation after heart procedures

This study looks at whether a comprehensive add-on treatment—starting with immune medicine and then a heart procedure when needed—can improve outcomes for people whose coronary artery disease is getting worse quickly. It focuses on cases where inflammation is likely driving new artery blockages or worsening chest pain.

Stent treatment versus medicines for blocked neck artery

This study compares a drug-coated stent placed in a neck (vertebral) artery versus best medical treatment with medicines and risk-factor control. It aims to reduce problems caused by a badly narrowed artery after recent stroke-like symptoms.

Study of inflammation-related coronary artery disease

This study compares two types of coronary artery disease: one linked to inflammation (IR-CAD) and the standard type (AS-CAD). If you have had a heart procedure and were recently hospitalized for worsening chest pain, this study may help doctors understand your condition better.

Test heart blood-flow measurements before and after TAVI

This study checks whether special heart tests can better understand “in-between” blocked heart arteries before and after TAVI (a valve replacement done through a catheter). It may help doctors choose the safest, most accurate treatment when coronary artery disease is unclear.

Registry for stent treatment in narrowed brain arteries in China

This study records outcomes for people with significant narrowing in brain arteries who have treatment using a drug-eluting stent. It may help doctors understand how well this approach works and what risks or benefits to expect.

Carotid artery narrowing treatment follow-up at clinic

This study follows people who are getting a procedure for carotid artery narrowing at the clinic. It aims to learn about outcomes after these treatments.

INR-CAD: inflammation-related coronary artery disease study

This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.

Carotid stenting for high-risk carotid surgery patients

This trial tests whether placing a stent in the narrowed carotid artery is a good option for people who are at high risk for the standard surgery (carotid endarterectomy). If you have significant blockages in your neck arteries and certain health or anatomical factors that make surgery riskier, this study may be for you.

Gut bacteria and recovery in brain artery narrowing

This study looks at how the bacteria in your gut might affect outcomes in people with narrowed brain arteries. Researchers will track your health over time to see if there are links between your gut bacteria and your recovery.

Study of a new treatment for blocked leg arteries

This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.

Shunt for carotid artery narrowing

This study tests a new device that is placed through the carotid artery in the neck to temporarily block blood flow during a procedure to open up a narrowed carotid artery. It might be an option for people who have high-risk features that make traditional surgery more challenging.

Brain and heart illness registry for adults in China

This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.

Carotid stent vs. medication for recent stroke risk

This trial tests if a carotid artery stent plus medication is better than medication alone at preventing another stroke in people who recently had a stroke or eye blockage caused by a non-narrowing but risky carotid plaque.