Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 435 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03711175Enrolling by invitation
Repairing a shoulder tendon after reverse shoulder replacement
This study looks at whether repairing a specific shoulder tendon (the subscapularis) improves outcomes after reverse shoulder replacement. You may be eligible if you’re getting a reverse shoulder implant because of severe arthritis and your tendon is strong enough to repair on MRI.
St Louis, MissouriAges 21 years+ - NCT03804853Recruiting
Rehab program after reverse shoulder replacement surgery
This trial studies a rehabilitation plan after reverse total shoulder arthroplasty (reverse shoulder replacement) to see if it improves recovery. If you are eligible, you may be guided through specific therapy and follow-up visits as part of the study.
Bloomington, MinnesotaAges 55 years+ - NCT01909375Recruiting
Joint replacement registry study for people getting new joints
This is a registry study that collects information about people in the US who are getting a total joint replacement. It may help researchers understand outcomes and improve care for patients like you.
Rosemont, IllinoisAges Any age - NCT06208267Recruiting
Tranexamic acid for pain and bleeding after hip or knee replacement
This study tests whether a medicine called tranexamic acid (TXA) can reduce pain, improve movement, and lessen bleeding after hip or knee replacement surgery. It is for adults having their first joint replacement at St. Mary's Hospital.
Montreal, QuebecAges 18 years+ - NCT05849961Recruiting
Follow-up study for an Exactech hip replacement
This study checks how people do after receiving a specific brand of hip replacement (Exactech Hip System). It looks at safety and outcomes using either new follow-up, past medical records, or both, to better understand how the device performs over time.
Tulsa, OklahomaAges 18 years+ - NCT06520306Enrolling by invitation
Ropivacaine with methylene blue for hip surgery pain
This trial tests if adding different amounts of methylene blue to a standard numbing medicine (ropivacaine) can improve pain relief, thinking ability, and hip movement after hip replacement surgery.
TaizhouAges 60–85 - NCT07655921Recruiting
Enhanced recovery after knee replacement surgery
This trial tests a special care plan called ERAS to help people recover faster after total knee replacement. It compares this plan to standard care to see if it reduces hospital stay and improves recovery.
Karachi, SindhAges 50–70 - NCT02301182Enrolling by invitation
Compare two hip implant types for younger hip arthritis
This trial compares two different hip implant designs in people ages 40–65 with primary hip osteoarthritis. It looks at how well the hip works afterward—especially function and everyday results.
AarhusAges 40–65 - NCT06268795Recruiting
Comparing biopsy vs. aspiration for shoulder/elbow revision surgery
This study compares two methods—biopsy (taking a small tissue sample) and aspiration (drawing fluid)—to see which one better detects infection in people having repeat shoulder or elbow replacement surgery. The results will help doctors choose the best test for future patients.
Wigan, LancashireAges 18 years+ - NCT07155837Enrolling by invitation
TENS for pain after first knee replacement surgery
This study tests if a TENS device, which uses mild electrical pulses to relieve pain, helps people recover better after their first total knee replacement. It might reduce pain and improve movement.
Adana, AdanaAges 18 years+ - NCT05030220Recruiting
Testing testosterone and a skin bacteria during shoulder surgery
This study looks at how testosterone levels and a common skin bacteria (Cutibacterium) may relate to outcomes around elective shoulder replacement surgery. Results could help improve how doctors prevent and understand infection risk or healing after surgery.
Seattle, WashingtonAges 18–89 - NCT07043127Recruiting
Strength training after hip replacement with blood flow restriction
This trial tests a new kind of physical therapy after hip replacement. It combines strength exercises with a special technique called blood flow restriction to see if it helps you recover muscle strength faster.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07225751Recruiting
MagnetOs Bone Graft vs. Your Own Bone for Foot Fusion
This study tests a new bone graft material (MagnetOs) against using your own bone for hindfoot or ankle fusion surgery. The goal is to see if the new material works just as well for helping bones heal together.
Vail, ColoradoAges 18–75 - NCT06193057Recruiting
Custom vs standard total ankle replacement trial
This study compares a custom-made artificial ankle joint to a standard one for people with arthritis in one ankle. If you are a candidate for a first-time ankle replacement, this trial could help find out which type of implant works best.
Bologna, BOAges 40–75 - NCT05279092RecruitingPhase 2
Testing two pain-control injections for knee replacement surgery
This Phase 2 study compares two ways of reducing nerve pain after knee replacement surgery (total knee arthroplasty). It looks at whether steroid-enhanced pain medicine works better than a different numbing injection to improve recovery and comfort.
New Haven, ConnecticutAges 18 years+ - NCT07600632Recruiting
Hip Replacement Surgery Outcomes Using Short Stem
This study reviews results from hip replacement surgery using a special short implant inserted through a small front-of-hip incision. Researchers want to understand how well this approach works and how long the implant lasts.
BolognaAges 18 years+ - NCT05653687Recruiting
Hip replacement surgery: X-ray guidance versus usual hand placement
This trial compares two ways of guiding hip replacement surgery during the operation. It may help improve how accurately the surgeon places the hip components and how well patients do afterward.
Lugano, Canton TicinoAges 18–90 - NCT07597538Recruiting
How Hip Replacement Changes Knee Position and Function
This study examines whether getting a hip replacement changes how your knee aligns and functions. Researchers will compare knee imaging before and after your surgery to understand this connection.
Asyut, Asyut GovernorateAges Any age - NCT06733597Recruiting
Bone density change after knee replacement with or without cement
This study looks at how bone density in the thigh bone changes after knee replacement surgery, comparing two ways of attaching the new joint (with cement or without). It may help people who have normal bone density or early bone thinning but not full osteoporosis.
Madison, WisconsinAges 55 years+ - NCT06120023Recruiting
Long-term follow-up of the Madison knee replacement system
This study follows patients in France who receive a Madison total knee replacement. It watches how well the knee works and how the patient feels over time, to make sure the implant is safe and effective.
Lyon, RhôneAges 18 years+ - NCT06748885Recruiting
Mpact 3D metal hip replacement study
This trial tests a new 3D-printed metal hip implant for people who need a first-time hip replacement. It aims to see how well the implant works and helps you recover.
NantesAges 18–75 - NCT07526831Recruiting
Pain Relief Methods for Knee Surgery: Two Nerve Block Approaches
This study compares two ways of numbing nerves around the knee during surgery to see which method reduces pain better after the operation. Both methods use safe, well-established pain-relief techniques.
Kayseri, TalasAges 18 years+ - NCT06464770Recruiting
Improving infection prevention before shoulder surgery
This study compares different ways to clean the skin before shoulder surgery to prevent infection. It might help if you are going to have shoulder surgery and want safer, more effective infection prevention.
Seattle, WashingtonAges 18–89 - NCT06025331Recruiting
BIO-RSA vs standard reverse shoulder replacement study
This study compares two types of reverse shoulder replacement: one that uses a bone graft (BIO-RSA) and one that doesn't. It aims to see if the BIO-RSA method gives better pain relief and function for people with arthritis, large rotator cuff tears, or failed prior cuff surgery.
Skien, TelemarkAges 45–80
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 435 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.