Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 448 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05653102Recruiting
Collecting data on a knee replacement system after surgery
This study collects real-world health and surgery records to better understand how the Truliant total knee replacement performs. It may help doctors and patients by improving future guidance on this knee system’s safety and effectiveness.
Aurora, ColoradoAges 18 years+ - NCT05849961Recruiting
Follow-up study for an Exactech hip replacement
This study checks how people do after receiving a specific brand of hip replacement (Exactech Hip System). It looks at safety and outcomes using either new follow-up, past medical records, or both, to better understand how the device performs over time.
Tulsa, OklahomaAges 18 years+ - NCT07828080Recruiting
Hip replacement using a newer stem design
This study looks at how well a newer type of hip replacement stem (called the Actis stem) works for people having their first hip replacement. It aims to see if this stem provides good outcomes for various hip conditions.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07817537RecruitingEarly Phase 1
Comparing two ways to give tranexamic acid during hip replacement
This study compares two ways of giving a medicine called tranexamic acid (which helps reduce bleeding) during total hip replacement surgery. The goal is to see which method is better at reducing blood loss during and after the operation.
AlexandriaAges 18 years+ - NCT07818343Recruiting
Comparing two knee replacement designs for revision surgery
This study compares two types of knee implants used when a previous knee replacement needs to be revised (re-done). It aims to see which design offers better outcomes for patients needing both parts of the implant replaced.
Washington D.C., District of ColumbiaAges 18–80 - NCT07813832Recruiting
Recovery study after knee or hip replacement
This study looks at why some people have problems after knee or hip replacement surgery. It follows patients for three years to understand complications and improve care.
MoscowAges 45 years+ - NCT07799818Recruiting
Joint replacement study for hip or knee
This study looks at how well hip or knee replacements work. If you are already scheduled for a replacement or a revision (a second replacement), you may be able to join.
Bonn, North Rhine-WestphaliaAges 18–100 - NCT06317870Recruiting
Nerve block vs spinal morphine for hip surgery pain
This trial compares two types of pain relief after a hip replacement: a nerve block (injecting numbing medicine near the hip) versus a small dose of morphine given through a spinal needle. It aims to find out which option works better with fewer side effects.
Lausanne, Canton of VaudAges 18 years+ - NCT07775248RecruitingPhase 4
Long-lasting pain relief after knee replacement
This trial tests a new type of pain medicine that is given during knee replacement surgery and slowly releases pain relief over several days. It may help reduce the need for opioid painkillers after surgery.
Grosse Pointe Farms, MichiganAges 18 years+ - NCT07767097Recruiting
Low-dose radiation after revision knee replacement for stiffness
This study tests whether a single low dose of radiation after revision knee replacement surgery can help reduce stiffness and improve knee movement in people who had a stiff knee after their first replacement. The radiation is given along with usual care after surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT07770932Recruiting
Pain relief after hip replacement surgery
This study compares two types of nerve blocks for pain relief after hip replacement surgery. It aims to find which method reduces pain and improves recovery.
Istanbul, BagcilarAges 18–80 - NCT05569161Recruiting
Testing a shoulder replacement called Embrace for 2 years
This study looks at how safe an Embrace reverse shoulder replacement is over two years and what results you can expect on imaging scans. You may qualify if you’re an adult with a shoulder problem that can be treated with this specific type of replacement and have recent CT or MRI scans.
MadridAges 18 years+ - NCT04728542Recruiting
Observational study comparing two osteoporosis treatment approaches
This is an observational study, meaning researchers watch what happens in real life rather than assigning a treatment by chance. It compares outcomes between people using ORIGIN® and VANGUARD® PS, to better understand how these approaches perform.
MainzAges 18 years+ - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT06644729Recruiting
Shoulder surgery long-term study
This study looks at how patients who had rotator cuff repair surgery between 2010 and 2014 are doing now, including their shoulder function and x-ray results. It helps doctors understand long-term outcomes and when more surgery like reverse shoulder replacement may be needed.
OsloAges 18–95 - NCT07694895Recruiting
AI-assisted education for knee replacement recovery
This trial tests if an AI-powered educational video before you get up and walk after knee replacement surgery can help reduce fear of movement and make you feel more ready to leave the hospital.
Kocaeli, İzmitAges 18–100 - NCT07696650Recruiting
Choose to Move Replacement Ready study
This study looks at a program called Choose to Move Replacement Ready (CTM-RR) for older adults and the people who help them get active. It tests how well the program works for activity coaches, participants, and healthcare referral partners.
Vancouver, British ColumbiaAges 50 years+ - NCT05807854Recruiting
Surgery options for large, repairable shoulder tendon tears
This trial compares two different ways to repair a large, repairable rotator cuff (shoulder tendon) tear. It may help you understand which surgical approach leads to better recovery after non-surgical treatments have already failed.
Portland, OregonAges 60–80 - NCT07655921Recruiting
Enhanced recovery after knee replacement surgery
This trial tests a special care plan called ERAS to help people recover faster after total knee replacement. It compares this plan to standard care to see if it reduces hospital stay and improves recovery.
Karachi, SindhAges 50–70 - NCT07655388Recruiting
Wound healing and dressing changes after hip replacement
This study compares different types of dressings and how often they should be changed after total hip replacement surgery. It aims to find the best way to help the surgical wound heal.
Novi SadAges 65–95 - NCT07647354Recruiting
Mako robotic joint replacement surgery registry study
This study collects information from patients undergoing hip or knee replacement surgery with either traditional or robotic-assisted techniques. Researchers track your recovery and joint function to understand how well these procedures work.
Jacksonville, FloridaAges 18 years+ - NCT07653295Recruiting
Study of Tıpmed revision hip replacement safety
This study follows patients who already had a revision hip replacement using the Tıpmed system. Researchers want to confirm the implant is safe and works well over time.
BalıkesirAges 18 years+ - NCT07651735Recruiting
Safety and Recovery Study of Tipmed Hip Replacement
This study tracks how well people recover after hip replacement surgery using the Tipmed hip implant system. Researchers will monitor your healing and implant performance over time to ensure the device works safely and effectively.
BalıkesirAges 18 years+ - NCT07651462Recruiting
Fasting Before Hip Surgery and Gut Health
This study tests whether fasting for 20 days before hip replacement surgery changes your gut bacteria in ways that might help your recovery. Researchers want to understand if this dietary approach affects how well you heal after the operation.
Berlin, State of BerlinAges 18–75
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 448 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.