Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04507412RecruitingPhase 4
IV steroid before shoulder surgery to reduce inflammation
This trial studies whether giving dexamethasone through a vein (an anti-inflammatory steroid) around the time of total shoulder replacement surgery improves outcomes. It may help lower inflammation and related discomfort, but you must meet specific health and medication safety criteria to join.
LuganoAges 58–85 - NCT04294693Recruiting
Study of total joint replacement in children and young adults
This study looks at outcomes after total joint replacement in people ages 10–25 at Children’s Hospital Colorado. It may help doctors better understand which patients do well after surgery (or after trying non-surgical pain treatments first).
Aurora, ColoradoAges 10–25 - NCT03511586Recruiting
Shoulder replacement outcomes registry
This study collects information from people having shoulder replacement surgery with an Arthrex implant. It helps doctors learn how well these implants work over time.
Phoenix, ArizonaAges 18–100 - NCT00527839Recruiting
Shoulder replacement patient registry at a single hospital
This is a non-interventional patient registry that follows people having total shoulder replacement. You help researchers by completing questionnaires, which may improve how shoulder replacement care is understood and planned.
New York, New YorkAges 18 years+ - NCT07879014Recruiting
Quiet knee protocol after knee replacement surgery
This study tests a special recovery plan after knee replacement surgery. It aims to see if this plan helps reduce pain and improve movement. You may be able to join if you are having one knee replaced due to arthritis.
Jacksonville, FloridaAges 18–100 - NCT04230616Recruiting
Testing a knee device to ease osteoarthritis pain
This study tests how well and how safely a knee treatment works for adults with painful knee osteoarthritis seen on X-ray. You might join if you need meaningful pain relief and help with daily function, and can complete required scans and study instructions.
Sint-Truiden, LimburgAges 18 years+ - NCT04247672Recruiting
Study of knee replacement outcomes using a specific knee implant
This study follows people who need knee replacement for “end-stage” knee osteoarthritis and will receive a specific knee implant system as part of routine care. It aims to measure how well the knee replacement works for patients over time, which may help improve future care.
Hoofddorp, North HollandAges 21–90 - NCT05461651Recruiting
Preventing knee infections after knee replacement
This study looks at ways to lower the risk of infection after knee replacement surgery (with or without vancomycin, an antibiotic). If you’re a good candidate, you may receive an approach aimed at preventing post-surgery infections and related complications.
Otwock, Masovian VoivodeshipAges 40 years+ - NCT04350255Recruiting
Study of new cup design during primary hip replacement
This study follows people getting a first-time hip replacement to see how a specific new hip “cup” (socket part) performs in real-world care. It may help improve future hip replacement choices, especially for patients who fit the study’s surgical and follow-up requirements.
Mölndal, Västra Götaland CountyAges 30–75 - NCT05649007Recruiting
Monitoring the Saphir hip stem after new hip replacement
This study watches how a specific hip replacement part (the Saphir stem) performs after primary hip surgery in everyday care. It helps doctors and manufacturers learn about safety and outcomes after the device is already in use.
ToulouseAges 18 years+ - NCT05685706Recruiting
Study of spine alignment after hip or knee replacement
This study looks at how the alignment of your spine relates to your walking and posture after hip or knee replacement surgery for wear-and-tear arthritis. It may help doctors better understand how to monitor recovery and long-term function.
Taichung, North DistrictAges Any age - NCT05936814Recruiting
Study measures knee alignment in severe varus osteoarthritis
This study focuses on people age 65+ with severe “varus” knee alignment osteoarthritis (wear-and-tear arthritis that affects how the knee lines up). It aims to use your knee measurements and data to better understand the condition and guide care.
AnkaraAges 65 years+ - NCT06025448Recruiting
Comparing two types of reverse shoulder replacement
This study compares two types of reverse shoulder replacements: one that uses a small piece of your own bone (BIO-RSA) and another that uses a special metal implant (MIO-RSA) to fill the socket. The goal is to see which one stays more stable in the bone after surgery.
OsloAges 45–80 - NCT06025331Recruiting
BIO-RSA vs standard reverse shoulder replacement study
This study compares two types of reverse shoulder replacement: one that uses a bone graft (BIO-RSA) and one that doesn't. It aims to see if the BIO-RSA method gives better pain relief and function for people with arthritis, large rotator cuff tears, or failed prior cuff surgery.
Skien, TelemarkAges 45–80 - NCT05892133Recruiting
Exercise program before knee replacement to improve recovery
This trial studies whether doing a structured exercise or “prehab” program before total knee replacement can improve knee function and patient satisfaction after surgery. It may help you recover better and feel more confident in your outcome.
Molde, Møre og RomsdalAges 50–80 - NCT07872826Enrolling by invitationPhase 3
Study of pain relief injection after hip replacement surgery
This study tests a new pain-relief injection given during hip replacement surgery to reduce pain after the operation. The goal is to help patients recover with less discomfort and possibly reduce the need for other pain medications.
ChangshaAges 18–80 - NCT04623593Recruiting
Study of cost and value of neck disc surgery
This study looks at how cost-effective (good value for the money) anterior neck disc surgery is for people with nerve or spinal cord symptoms. If you need this type of operation, it may help doctors better choose treatments and plan healthcare resources.
Maastricht, LimburgAges 18 years+ - NCT07863557RecruitingPhase 4
Early wear of hip replacement liners
This trial tests how well a type of hip replacement called a dual mobility cup holds up over time, focusing on early signs of wear in the plastic liner. It aims to see if this implant lasts longer and works better for people with hip arthritis or other hip conditions.
Uppsala, Uppsala CountyAges 18–75 - NCT07872670Recruiting
Virtual reality to help recovery after hip or knee replacement
This study uses virtual reality (a computer-generated 3D environment you wear a headset for) alongside your usual care to help with recovery after hip or knee replacement surgery. It may help reduce pain or improve how well you move after surgery.
Inverness, HighlandsAges 18 years+ - NCT06074744Recruiting
Nerve blocks for knee replacement pain relief
This study compares two types of nerve blocks (subsartorial and femoral) to see which provides better pain control after knee replacement surgery. Both are injections that numb the nerves around your knee to help with recovery.
LucerneAges 18 years+ - NCT06323018Recruiting
Remote preconditioning for cemented hip replacement recovery
This trial tests whether a simple, safe treatment called remote ischemic preconditioning (using a blood pressure cuff on your arm just before surgery) can help people recover better after cemented hip replacement. It is for patients aged 66 and older who are scheduled for this surgery.
Tartu, TartuAges 65–90 - NCT04801680Recruiting
3D metal hip cup for painful hip arthritis
This trial studies a specific type of 3D metal cup used during hip replacement surgery. It aims to see how well it works over time in people who need a first (primary) total hip replacement.
Milan, MIAges 18–75 - NCT05785364Recruiting
Study of a hip implant used in total hip replacement
This study follows people who get a specific hip socket implant (the Mpact 3D Metal MonoCER) after total hip replacement. It’s mainly to monitor how the device is working in real-world use.
GenevaAges 18–75 - NCT06426251Recruiting
Light therapy for knee replacement recovery
This trial tests whether a special light therapy (photobiomodulation) can help reduce pain and speed healing after total knee replacement. If you're having knee replacement and don't have complications like infection or open wounds, you may be eligible.
HsinchuAges 20 years+
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 450 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.