Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 435 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04828954Recruiting
Testing different immobilization plans after thumb joint surgery
This study compares different ways of keeping your thumb still (immobilizing it) after thumb base joint surgery. It aims to see which immobilization approach leads to better recovery and hand function.
Chicago, IllinoisAges 40 years+ - NCT06888908Recruiting
Blood volume changes during hip replacement surgery
This trial measures how blood volume and fluids shift in the body during and after hip replacement surgery. It helps doctors better understand fluid management for patients having this procedure.
CopenhagenAges 18 years+ - NCT06777160Recruiting
Predicting bone cement risks with AI
This study uses artificial intelligence to predict a rare but serious reaction called bone cement implantation syndrome during hip and knee replacement surgeries. It may help doctors better prepare and protect you.
ErzurumAges 18 years+ - NCT06758297Recruiting
AI motivational talk after knee replacement
This study tests whether an artificial intelligence-guided motivational conversation can help reduce fear of moving after knee replacement surgery, and improve how much you can move.
Samsun, SamsunAges 18 years+ - NCT06754150Recruiting
Shoulder Innovations shoulder replacement registry study
This study follows people who have or will have a shoulder replacement using a Shoulder Innovations device. Researchers will collect information on how well the device works and how your shoulder feels over time.
Birmingham, AlabamaAges 18 years+ - NCT06321042Recruiting
Knee replacement study using sensor-guided implant placement
This study tests whether using small motion sensors during knee replacement surgery leads to better outcomes. It is for people aged 50–84 with severe knee pain from arthritis or bone damage who are scheduled for a first-time cemented total knee replacement.
Bologna, ItaliaAges 50–85 - NCT06078189Recruiting
Thumb joint surgery for arthritis: comparing two procedures
This trial tests two surgical treatments for thumb base arthritis (rhizarthrosis) when other treatments like splints and injections haven't worked. It compares a newer joint implant (arthroplasty) with a standard procedure to remove a small bone (trapezectomy). The goal is to see which helps patients recover hand function better.
ParisAges 45–85 - NCT06080152Recruiting
Wheeled device use after knee replacement
This study observes how people use wheeled devices (like walkers) after a total knee replacement. It helps doctors understand what patients need during recovery.
Redwood City, CaliforniaAges 18–99 - NCT06038240Recruiting
Pain self-management program for knee replacement
This study is testing a program to help people manage pain on their own before and after total knee replacement surgery. It aims to improve recovery and reduce reliance on pain medications.
Charlottesville, VirginiaAges 18–85 - NCT05785364Recruiting
Study of a hip implant used in total hip replacement
This study follows people who get a specific hip socket implant (the Mpact 3D Metal MonoCER) after total hip replacement. It’s mainly to monitor how the device is working in real-world use.
GenevaAges 18–75 - NCT05818891Recruiting
Study of a hip implant for people needing first hip replacement
This trial studies a specific hip implant (from Medacta) for people who need their first total hip replacement. It aims to see how well the implant works and whether patients recover mobility safely.
Dracy-le-FortAges 18–80 - NCT05699031Recruiting
Shoulder replacement recovery care by telehealth
This trial tests whether follow-up care by phone or video (telehealth) helps people recover better after a total shoulder replacement. It may be helpful by making rehab guidance easier to follow at home.
GhentAges 60 years+ - NCT05736549RecruitingPhase 2
Tested stronger pain-blocking shot for knee replacement surgery
This Phase 2 study compares two ways to reduce pain after total knee replacement (TKA): a steroid-enhanced nerve block versus a numbing shot called Exparel. It aims to see which option improves comfort and recovery after surgery done with spinal anesthesia.
New Haven, ConnecticutAges 18 years+ - NCT05516381Recruiting
Navigation-assisted knee replacement with two alignment methods
This study tests a computer-guided technique for total knee replacement and compares two ways of aligning the new joint. It may help improve how accurately the surgery is done, which could affect comfort and function afterward.
BarcelonaAges 18 years+ - NCT05391828Recruiting
Testing a new knee robot and app support for knee arthritis
This study looks at whether a robot-assisted knee replacement plus remote tracking with an Apple Watch and a smartphone app helps people do better after surgery. You may be eligible if you’re an adult getting a planned (not replacement) knee surgery for arthritis and can use the required devices.
New York, New YorkAges 18 years+ - NCT04801680Recruiting
3D metal hip cup for painful hip arthritis
This trial studies a specific type of 3D metal cup used during hip replacement surgery. It aims to see how well it works over time in people who need a first (primary) total hip replacement.
Milan, MIAges 18–75 - NCT05159739Enrolling by invitation
Study of family genetic risk for joint implant infections
This study looks at whether certain families have a higher genetic risk for infections around joint implants. It may help researchers understand who is more at risk and how to prevent these infections.
Salt Lake City, UtahAges 18–100 - NCT04728542Recruiting
Observational study comparing two osteoporosis treatment approaches
This is an observational study, meaning researchers watch what happens in real life rather than assigning a treatment by chance. It compares outcomes between people using ORIGIN® and VANGUARD® PS, to better understand how these approaches perform.
MainzAges 18 years+ - NCT05175300Recruiting
Vitamin E hip implant for young, active hip replacements
This study tests a hip replacement implant that uses Vitamin E–doped material to see how well it works for young, active adults. It’s meant for people who need a total hip replacement, and compares outcomes over follow-up visits.
LyonAges 18–65 - NCT04629391Recruiting
Reverse vs standard shoulder replacement for arthritis
This study compares two types of shoulder replacement surgery for people with arthritis and an intact rotator cuff. The goal is to see which operation works better and is more reliable for your type of shoulder problem.
MeyrinAges 65–85 - NCT04692714Recruiting
Cemented vs cement-free robotic knee replacement surgery
This trial compares two ways surgeons can attach a knee replacement using robotic-assisted surgery: with cement or without cement. It may help improve how well the new knee lasts and how patients recover after a first-time knee replacement.
LyonAges 50–80 - NCT05569161Recruiting
Testing a shoulder replacement called Embrace for 2 years
This study looks at how safe an Embrace reverse shoulder replacement is over two years and what results you can expect on imaging scans. You may qualify if you’re an adult with a shoulder problem that can be treated with this specific type of replacement and have recent CT or MRI scans.
MadridAges 18 years+ - NCT05412615Recruiting
Meniscal graft surgery for wrist arthritis
This trial studies whether using a donor meniscus (meniscal allograft) during wrist replacement surgery can help people with painful wrist osteoarthritis. It’s mainly for certain types of arthritis changes in the wrist (SLAC or SNAC) and specific age ranges.
Englewood, ColoradoAges 30–80 - NCT04454203RecruitingPhase 4
Local anesthetic catheter to reduce tourniquet-related blood pressure spikes
This Phase 4 trial tests whether a local anesthetic catheter placed near a nerve and artery can prevent high blood pressure caused by a tourniquet during total ankle replacement surgery. If it works, it may make recovery safer and more comfortable for some patients.
Durham, North CarolinaAges 18–75
Hear when a new Arthroplasty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 435 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.