Clinical trials
Shoulder Arthroplasty clinical trials
Below are recruiting shoulder arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 64 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07604714Recruiting
Shoulder Replacement Surgery: Testing a Bone-Removal Technique
This trial compares two surgical approaches for reverse total shoulder replacement—a procedure that replaces a damaged shoulder joint. Researchers are testing whether removing part of a shoulder bone (the coracoid) helps improve your arm's ability to rotate inward after surgery.
AnnecyAges 18 years+ - NCT05788614Recruiting
Testing shoulder implant movement after reverse shoulder arthroplasty
This study looks at how the shoulder changes position (“reverts”) after a reverse shoulder replacement. It may help doctors better understand what to expect after surgery in people with certain age-related shoulder wear and tear.
Córdoba, CordobaAges 60 years+ - NCT04228419Recruiting
Shoulder replacement approach comparison for advanced shoulder arthritis
This trial compares two ways of doing shoulder arthroplasty (shoulder replacement) for people with advanced shoulder arthritis who have not improved with non-surgical treatments. It may help determine which approach works better for pain and function.
Edmonton, AlbertaAges 65 years+ - NCT05487274Recruiting
Shoulder arthritis surgery plan for specific shoulder bone alignment
This study compares two types of surgery for advanced shoulder osteoarthritis when the shoulder socket is turned backward more than 15 degrees. It aims to see which surgical approach works best for pain and function when the bone alignment issue can be corrected.
Ottawa, OntarioAges 65 years+ - NCT07651215Enrolling by invitation
Short-Stem Shoulder Replacement Surgery Outcomes Study
This study looks at how well a newer type of shoulder replacement surgery works. Researchers are checking X-rays and patient function for people who had this specific short-stem surgery at least 2 years ago.
LinzAges 18 years+ - NCT07410650Enrolling by invitation
Shoulder replacement that spares a key muscle
This study is testing a shoulder replacement surgery that avoids cutting a key muscle (the subscapularis). It may help patients recover shoulder function more quickly with less pain.
Salt Lake City, UtahAges 18–90 - NCT06902714RecruitingPhase 3
Tranexamic acid for shoulder replacement recovery
This study tests whether taking an oral medicine called tranexamic acid (TXA) before and after shoulder replacement surgery can reduce bleeding and improve recovery. It is for adults scheduled for a total shoulder replacement who are generally healthy.
Birmingham, AlabamaAges 18–79 - NCT06831422Recruiting
Antimicrobial Wash During Shoulder Replacement
This study tests whether washing the surgical site with a special antimicrobial liquid after the incision can lower the risk of infection during shoulder replacement surgery. It may help people who are already planning a first-time shoulder replacement.
Detroit, MichiganAges 18 years+ - NCT06891378Recruiting
Home rehab app for patients after shoulder replacement surgery
This trial tests a digital rehab program you can do at home after reverse total shoulder replacement. The goal is to see if an app-based exercise plan helps you recover safely and effectively.
Seoul, Irwon-ro 81Ages 50 years+ - NCT07721415Enrolling by invitationPhase 4
Iodine drapes for shoulder replacement surgery
This trial is testing whether using iodine drapes during a first-time shoulder replacement reduces infection risk. It is for men who are planning this surgery.
Philadelphia, PennsylvaniaAges 18 years+ - NCT00527839Recruiting
Shoulder replacement patient registry at a single hospital
This is a non-interventional patient registry that follows people having total shoulder replacement. You help researchers by completing questionnaires, which may improve how shoulder replacement care is understood and planned.
New York, New YorkAges 18 years+ - NCT04507412RecruitingPhase 4
IV steroid before shoulder surgery to reduce inflammation
This trial studies whether giving dexamethasone through a vein (an anti-inflammatory steroid) around the time of total shoulder replacement surgery improves outcomes. It may help lower inflammation and related discomfort, but you must meet specific health and medication safety criteria to join.
LuganoAges 58–85 - NCT07406893Recruiting
Reducing Infection Risk in Shoulder Replacement Surgery
This trial tests whether a special gel (Prontosan) applied during shoulder replacement surgery can reduce the risk of infection. It is for men having their first shoulder replacement.
St Louis, MissouriAges 18 years+ - NCT07280195Enrolling by invitationPhase 4
Comparing pain relief after shoulder replacement
This study compares two ways to manage pain after shoulder replacement surgery: a long-acting numbing medicine (ZYNRELEF) versus a temporary nerve block catheter. It aims to see which provides better pain control and recovery.
St Louis, MissouriAges 18 years+ - NCT06848023Enrolling by invitation
Shoulder replacement vs tendon repair in older adults
This study compares how well two different shoulder surgeries—reverse total shoulder replacement and rotator cuff repair—work for people 60 and older, at least one year after the operation. If you meet the age and surgery requirements, your results could help doctors decide which procedure is better for older adults.
Germantown, TennesseeAges 60–95 - NCT04984291Recruiting
Study of shoulder replacement implants for eligible adults
This trial looks at a specific shoulder replacement implant and follow-up care for people who need a shoulder arthroplasty (shoulder replacement) for certain joint problems or fractures. You may be a candidate if you can take part in required visits and your shoulder muscles and bone are suitable.
Irvine, CaliforniaAges 20 years+ - NCT06733480Recruiting
Band Connect for physical therapy after shoulder surgery
This study tests a new physical therapy tool called Band Connect, which may help people follow their rehab exercises better after shoulder surgery. Researchers want to see if it improves satisfaction and recovery outcomes.
Cleveland, OhioAges 18–89 - NCT06869343Recruiting
Early vs. Late Rehab After Shoulder Replacement for Fracture
This study compares starting shoulder rehab early (2 weeks after surgery) versus at the standard time after a reverse total shoulder replacement for a broken shoulder. It aims to see which approach helps you recover better.
Charlottesville, VirginiaAges 50–85 - NCT06729983Recruiting
Tendon lengthening during reverse shoulder replacement
This study tests whether slightly lengthening a tendon during reverse shoulder replacement improves outcomes. It's for adults getting their first reverse replacement at Loyola sites.
Maywood, IllinoisAges 18 years+ - NCT07145957Recruiting
Pre-surgery exercise program for better shoulder rotation after replacement
This study tests if a special exercise program before shoulder replacement surgery improves how well you can rotate your arm inward after the operation. Participants do exercises for 6 weeks before surgery and are followed for 2 years.
Gainesville, FloridaAges 40–80 - NCT03511586Recruiting
Shoulder replacement outcomes registry
This study collects information from people having shoulder replacement surgery with an Arthrex implant. It helps doctors learn how well these implants work over time.
Phoenix, ArizonaAges 18–100 - NCT05789784Enrolling by invitation
Using a shoulder-mobility app after shoulder replacement
This trial tests whether the Zimmer Biomet mymobility smartphone app improves outcomes after a reverse total shoulder replacement. It may help by supporting follow-up exercises and tracking progress after surgery.
Palm Beach Gardens, FloridaAges 18 years+ - NCT06920459Recruiting
Zimmer Biomet Shoulder Replacement Study
This study is testing a shoulder replacement system made by Zimmer Biomet to see how well it works for people with severe shoulder problems, like arthritis or fractures. If you qualify, you would receive the implant and be asked to come back for regular checkups to track your recovery.
PforzheimAges 20 years+ - NCT03806881Enrolling by invitation
Follow-up after shoulder replacement using a patient-specific implant
This study follows people after a primary or revision shoulder joint replacement when the shoulder socket bone has severe damage. It checks long-term outcomes and how well the patient-specific implant and required therapy work for recovery.
HerentalsAges 18 years+
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Shoulder Arthroplasty trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for shoulder arthroplasty?
- Yes. Clin2 currently lists 64 recruiting shoulder arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shoulder arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shoulder arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.