Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 442 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06203756Enrolling by invitation
Robotic-Assisted Knee Replacement Outcomes Study
This study tests a robotic-assisted system for knee replacement surgery. It aims to see how well patients do with the robotic help.
Flagstaff, ArizonaAges Any age - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+ - NCT06010979Recruiting
Knee replacement with digital help study
This study looks at knee replacement surgery done with digital tools like robots or computer guidance. It may help people with knee arthritis find better ways to have surgery and recover.
Beijing, Beijing MunicipalityAges Any age - NCT06251869Recruiting
Electrocautery vs. Scalpel in Joint Replacement Surgery
This trial compares two surgical tools—electrocautery and a cold knife (scalpel)—to see which works better during joint replacement surgery. It aims to find the best way to make incisions, which could mean less bleeding and faster healing.
Cluj-Napoca, ClujAges 18–90 - NCT07604714Recruiting
Shoulder Replacement Surgery: Testing a Bone-Removal Technique
This trial compares two surgical approaches for reverse total shoulder replacement—a procedure that replaces a damaged shoulder joint. Researchers are testing whether removing part of a shoulder bone (the coracoid) helps improve your arm's ability to rotate inward after surgery.
AnnecyAges 18 years+ - NCT04226339Recruiting
Test walking analysis after knee replacement, different alignment methods
This study compares two ways of aligning the knee during a total knee replacement and checks how people walk afterward using a walking test. It may help doctors choose the alignment method that best supports safer, smoother walking.
LyonAges 55–80 - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT07464665Recruiting
Comparing two hip socket implants for first-time hip replacement
This trial compares two types of hip socket implants (dual-mobility cups vs. standard cups) during first-time hip replacement through the front of the hip. It aims to see which type may reduce the risk of dislocation after surgery.
BrugesAges 18 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07524387Recruiting
Nerve blocks for better leg strength after knee replacement
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Ichinomiya, Aichi-kenAges 20 years+ - NCT07552415Recruiting
Joint Immobilization After Knee Replacement Revision Surgery
This study tests whether keeping your knee still for a period after revision knee replacement surgery helps improve how well you can bend and straighten it. Researchers want to see if immobilization (using a brace or cast) helps you regain better movement compared to standard care.
New York, New YorkAges 18 years+ - NCT06880497Recruiting
Comparing knee sounds after two types of knee replacement
This study compares how much noise the knee makes (and how it feels to the patient) after two different kinds of total knee replacement surgery. It aims to help patients know what to expect after surgery.
AuxerreAges 18 years+ - NCT05858086Recruiting
Physical therapy clearance before same-day knee or hip surgery
This study looks at whether you need to be “cleared” by physical therapy before going home the same day as knee (TKA) or hip (THA) replacement surgery. It may help determine the safest and most efficient discharge plan for patients who can go home with support right after surgery.
Baltimore, MarylandAges 18–90 - NCT05044767Recruiting
Hip replacement study using specific implant brands
This study checks how safe and how well specific hip replacement implants work after hip replacement surgery. You might be eligible if your surgeon plans to use an ATF Implants and/or Lapé Médical prosthesis and you don’t have certain health issues that can make surgery riskier.
BordeauxAges Any age - NCT04095637Recruiting
Compare two types of partial knee replacement surgeries
This study compares two implant types used for a partial knee replacement (only the inside/medial part) for people with “wear-and-tear” arthritis in that compartment. It looks to see which option leads to better outcomes after surgery and follow-up.
LondonAges 40–80 - NCT04277416Enrolling by invitation
Testing a new hip replacement system and how patients do
This study follows people getting a primary total hip replacement using the Entrada hip system to see how long it lasts and how well it works. You may be offered this specific hip implant and would be followed through study visits to measure recovery and outcomes.
Portland, OregonAges 18–80 - NCT03286868Recruiting
Tested knee replacement alignment during knee surgery
This study looks at how a specific computer/measurement approach (“Verasense”) helps position the knee during total knee replacement for people with knee arthritis. It may help improve how the new knee fits and aligns as you recover.
Halifax, Nova ScotiaAges 21–80 - NCT07086716Recruiting
Frailty study for hip or knee replacement patients
This study looks at frailty in people who have had a planned hip or knee replacement. It aims to understand how frailty affects recovery.
Rovato, BSAges 18 years+ - NCT07410650Enrolling by invitation
Shoulder replacement that spares a key muscle
This study is testing a shoulder replacement surgery that avoids cutting a key muscle (the subscapularis). It may help patients recover shoulder function more quickly with less pain.
Salt Lake City, UtahAges 18–90 - NCT06971757Recruiting
Is yearly check-up after hip or knee replacement needed?
This study looks at whether routine check-ups one year after hip or knee replacement are helpful or unnecessary. If you've had or are scheduled for a first hip or knee replacement for arthritis, you may be able to join.
AmsterdamAges 50 years+ - NCT06354543Recruiting
A study on Teknimed bone cement for joint replacement
This study is looking at how well Teknimed bone cements and cement restrictors work for people who need a joint replacement (like a hip or knee). If you are scheduled for a joint replacement or have already had one using these products since 2016, you may be able to join.
Brive-la-Gaillarde, AquitaineAges 18 years+ - NCT05828810Recruiting
Testing antiseptic skin cleaning during hip or knee revision surgery
This study checks whether an antiseptic method for cleaning the skin before surgery is safe and helpful for patients having a repeat (revision) hip or knee replacement. It may help reduce the risk of infection related to surgery.
Barrie, OntarioAges 18 years+ - NCT06839807Recruiting
Testing a new device for knee replacement loosening
This study tests a new device (AtMoves Knee System) to help diagnose if a knee replacement is loose. It is for people who have had a knee replacement and have symptoms that might mean the implant is loose, but standard tests have not given a clear answer.
Nijmegen, GelderlandAges 18 years+
Hear when a new Arthroplasty trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 442 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.