Clinical trials
Arthroplasty clinical trials
Below are recruiting arthroplasty clinical trials, each written for real people, not researchers. We’re tracking 450 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07848126Recruiting
Foam rolling after knee replacement surgery
This study tests whether using a foam roller after knee replacement surgery helps reduce pain and improve movement. If you are having your first knee replacement, this may help you recover faster.
Izmir, BalçovaAges 40 years+ - NCT06203756Enrolling by invitation
Robotic-Assisted Knee Replacement Outcomes Study
This study tests a robotic-assisted system for knee replacement surgery. It aims to see how well patients do with the robotic help.
Flagstaff, ArizonaAges Any age - NCT06010979Recruiting
Knee replacement with digital help study
This study looks at knee replacement surgery done with digital tools like robots or computer guidance. It may help people with knee arthritis find better ways to have surgery and recover.
Beijing, Beijing MunicipalityAges Any age - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+ - NCT06251869Recruiting
Electrocautery vs. Scalpel in Joint Replacement Surgery
This trial compares two surgical tools—electrocautery and a cold knife (scalpel)—to see which works better during joint replacement surgery. It aims to find the best way to make incisions, which could mean less bleeding and faster healing.
Cluj-Napoca, ClujAges 18–90 - NCT04226339Recruiting
Test walking analysis after knee replacement, different alignment methods
This study compares two ways of aligning the knee during a total knee replacement and checks how people walk afterward using a walking test. It may help doctors choose the alignment method that best supports safer, smoother walking.
LyonAges 55–80 - NCT07604714Recruiting
Shoulder Replacement Surgery: Testing a Bone-Removal Technique
This trial compares two surgical approaches for reverse total shoulder replacement—a procedure that replaces a damaged shoulder joint. Researchers are testing whether removing part of a shoulder bone (the coracoid) helps improve your arm's ability to rotate inward after surgery.
AnnecyAges 18 years+ - NCT07524387Recruiting
Nerve blocks for better leg strength after knee replacement
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Ichinomiya, Aichi-kenAges 20 years+ - NCT07464665Recruiting
Comparing two hip socket implants for first-time hip replacement
This trial compares two types of hip socket implants (dual-mobility cups vs. standard cups) during first-time hip replacement through the front of the hip. It aims to see which type may reduce the risk of dislocation after surgery.
BrugesAges 18 years+ - NCT07324954RecruitingPhase 1
Methylene blue for knee replacement surgery
This study tests if using a blue dye called methylene blue during knee replacement surgery can help doctors see and clean out infections better. It may help people having a first-time knee replacement or those with an infected knee replacement.
Miami, FloridaAges 18 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT07053943Enrolling by invitation
Comparing single vs. multiple antibiotic doses for hip and knee replacement
This study compares two ways of giving antibiotics before hip or knee replacement surgery to see which one leads to fewer infections needing another surgery. It may help doctors choose the best antibiotic approach for patients having their first joint replacement.
Amsterdam, North HollandAges Any age - NCT05044767Recruiting
Hip replacement study using specific implant brands
This study checks how safe and how well specific hip replacement implants work after hip replacement surgery. You might be eligible if your surgeon plans to use an ATF Implants and/or Lapé Médical prosthesis and you don’t have certain health issues that can make surgery riskier.
BordeauxAges Any age - NCT07864896RecruitingPhase 3
Study of a new pain medicine after knee replacement surgery
This trial tests a new oral pain medicine called suzetrigine for people who have a knee replacement. It aims to see if it helps control pain after surgery better or with fewer side effects than usual care.
New York, New YorkAges 18–80 - NCT07871487Recruiting
Brain protein changes after hip or knee replacement surgery
This study looks at whether having hip or knee replacement surgery with spinal anesthesia affects certain proteins in the brain that are linked to memory and thinking. It compares people having surgery with people who have arthritis but are not having surgery, to help understand if the surgery causes any short-term brain changes.
UppsalaAges 55–75 - NCT07851597Recruiting
Comparing surgical approaches for hip replacement surgery
This study compares two different surgical approaches for total hip replacement in people with hip osteoarthritis. Both approaches are standard, and the study looks to see if one leads to better recovery and long-term outcomes.
GävleAges 60–80 - NCT07840391Recruiting
Recovery after same-day knee replacement surgery
This study looks at how your physical activity, sleep, and knee function change after you go home the same day as your knee replacement surgery. It aims to help you recover better by understanding these factors.
TampereAges Up to 80 years - NCT07839403Recruiting
Comparing two types of hip replacement for arthritis
This study compares two types of hip replacement surgery: a newer option that preserves more bone (ceramic hip resurfacing) and a standard total hip replacement. Participants will wear a small activity monitor to see how their activity levels change after surgery, which may help doctors understand which procedure leads to a more active recovery.
DanderydAges 18 years+ - NCT07598552Recruiting
Brain Function Changes After Same-Day Hip or Knee Surgery
This study checks whether patients who have hip or knee replacement surgery and go home the same day experience any temporary changes in thinking or memory. Researchers want to understand how anesthesia and surgery affect the brain in the short term.
SvendborgAges 70 years+ - NCT07577869Recruiting
Nerve blocks for pain relief after knee replacement
This trial tests two types of numbing injections (nerve blocks) around the knee to help manage pain after total knee replacement surgery. The goal is to see if these injections reduce pain and improve recovery compared to standard pain treatment.
Kayseri, KocasinanAges 18–80 - NCT07551856Recruiting
Robotic vs. manual knee replacement surgery for arthritis
This study compares two ways to perform knee replacement surgery for osteoarthritis: traditional manual surgery versus robotic-assisted surgery. Both are standard approaches; the trial tests whether robotic guidance improves how well your knee works after surgery.
Glasgow, ScotlandAges 18 years+ - NCT07552415Recruiting
Joint Immobilization After Knee Replacement Revision Surgery
This study tests whether keeping your knee still for a period after revision knee replacement surgery helps improve how well you can bend and straighten it. Researchers want to see if immobilization (using a brace or cast) helps you regain better movement compared to standard care.
New York, New YorkAges 18 years+ - NCT06676189Recruiting
Comparing two types of plastic knee implants for replacement
This study compares two different types of plastic knee implants (polyethylene) used in total knee replacement surgery. The goal is to see which one works best for patients with knee arthritis.
Clermont-FerrandAges 18–90 - NCT06280352Recruiting
Robotic vs custom knee replacement trial
This study compares two modern ways of doing knee replacement: robot-assisted surgery versus a custom-made implant tailored to your knee shape. It aims to see which approach leads to better recovery and function for people with osteoarthritis.
Graz, StyriaAges 40–90
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Common questions
- Are there clinical trials for arthroplasty?
- Yes. Clin2 currently lists 450 recruiting arthroplasty studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthroplasty trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthroplasty trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.