Clinical trials
Autoimmunity clinical trials
Below are recruiting autoimmunity clinical trials, each written for real people, not researchers. We’re tracking 341 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04280510Recruiting
Study of immune-related gut illnesses in adults
This study looks at adults with immune-related stomach and intestine problems to better understand what may cause them. If you qualify, you can share information and consent to help researchers learn how these conditions work.
CréteilAges 18 years+ - NCT06347718RecruitingPhase 1/Phase 2
Car-T cells for autoimmune disease
This study tests a type of immunotherapy called CAR-T cells for people with certain autoimmune diseases like lupus, scleroderma, or myositis. It aims to see if this treatment can help when standard medicines haven't worked well enough.
Erlangen, BavariaAges 18 years+ - NCT06321588Recruiting
Autoimmune dementia: predicting antibodies in new cognitive decline
This study looks for certain antibodies that might be causing your new memory or thinking problems. It aims to find patterns that could help diagnose autoimmune dementia earlier.
Bologna, BolognaAges 40–90 - NCT06308978RecruitingPhase 1
Study of FT819 for B-cell autoimmune diseases
This trial tests a new cell therapy, FT819, for people with certain autoimmune diseases like lupus, vasculitis, myositis, or scleroderma that haven't improved with at least two previous treatments. The goal is to see if it can help control the disease.
Beverly Hills, CaliforniaAges 12–70 - NCT06069583Recruiting
Support program for adults with type 1 diabetes
This trial tests an online support platform to help adults with type 1 diabetes manage their condition. If you live in Canada, have internet access, and can read English or French, you may be able to join.
Montreal, QuebecAges 18 years+ - NCT06285279RecruitingPhase 1
CAR-T cell therapy for hard-to-treat autoimmune kidney diseases
This trial tests a new type of cell therapy called CAR-T cells that target two proteins (BCMA and CD19) to treat autoimmune kidney diseases that are not responding to standard treatments. The goal is to see if this therapy can help control the disease and improve kidney function.
Nanjing, JiangsuAges 18–65 - NCT06235580Recruiting
Genetics and immune-brain health study
This study looks at genetic diseases that affect the immune system and the brain. It aims to better understand these conditions by comparing patients, their relatives, and healthy controls.
Paris, Île-de-France RegionAges Any age - NCT06213090Recruiting
Study on patterns of neurodevelopmental disorders
This study looks at patterns of brain development issues in children who visit a specific medical center. It may help doctors understand these conditions better.
Phoenix, ArizonaAges Any age - NCT05029336RecruitingPhase 2
Stem cell transplant using your own cells for autoimmune disease
This Phase 2 study tests an autologous stem cell transplant (a treatment using your own blood-forming stem cells) for severe systemic sclerosis or severe lupus. The goal is to reset the immune system to help control the autoimmune disease.
Philadelphia, PennsylvaniaAges 8–25 - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Phoenix, ArizonaAges 12 years+ - NCT06037187Recruiting
Blood clotting study for immune skin diseases
This study looks at how immune-related skin diseases like bullous pemphigoid and lupus affect blood clotting. The results could help doctors better understand and manage clotting risks in these patients.
Omaha, NebraskaAges 19 years+ - NCT05982925Recruiting
Brain imaging study in multiple sclerosis
This study uses MRI scans to look at how multiple sclerosis affects the outer layer of the brain over time. It aims to learn more about the disease to help improve future treatments.
New York, New YorkAges 18 years+ - NCT05889806Enrolling by invitation
Study uses blood and tissue samples for gene and protein testing
This study collects and analyzes your donated samples (like blood or other biospecimens) to look for patterns in genes and proteins. The results may help researchers understand disease biology and improve future tests or treatments.
New Orleans, LouisianaAges 18 years+ - NCT05859997Enrolling by invitation
CAR-T cell therapy for active autoimmune disease flare-ups
This study tests an immune-cell treatment (CAR-T, called BRL-301) in people with certain autoimmune diseases that are active and hard to control. It may help your immune system calm down if standard treatments have not worked or your disease has returned.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05875155Recruiting
Saving eggs by freezing ovarian tissue during cancer or surgery care
This trial looks at freezing ovarian tissue to help protect future fertility for people who may lose ovarian function from medical treatments or ovarian surgery. It may help you preserve the chance to have children later when egg or embryo freezing alone isn’t an option.
Pittsburgh, PennsylvaniaAges Up to 39 years - NCT05787574RecruitingPhase 2
Reducing inflammation before stem cell transplant in immune disorders
This Phase 2 study tests medicines that calm inflammation before the first stem cell transplant. It aims to make transplant safer and more effective for people with certain inherited immune regulation or inflammatory conditions.
San Francisco, CaliforniaAges Any age - NCT05789030Recruiting
Treating IgG4-related disease with mild steroid starts
This trial is studying treatment plans for people with IgG4-related disease that affects a surface (superficial) organ area. It focuses on people who are newly diagnosed or have come back and who need to start or continue steroid medicine at a low dose.
BeijingAges 18–75 - NCT05671757RecruitingPhase 1/Phase 2
Daratumumab for primary antiphospholipid syndrome
This early-phase study tests daratumumab, an immune-targeting drug, for people with primary antiphospholipid syndrome (APS). It aims to see whether it can reduce APS activity and improve outcomes while you continue your usual blood-thinning treatment.
Baltimore, MarylandAges 18–65 - NCT05435547RecruitingPhase 4
Pre-surgery steroid medicine for autoimmune thyroid disease
This trial tests whether taking corticosteroids (anti-inflammatory medicines) before thyroid surgery is safe and helpful for people with autoimmune thyroid disease. It focuses on Graves’ or Hashimoto’s disease patients who are planning total thyroid removal.
Indianapolis, IndianaAges 18 years+ - NCT05368220Enrolling by invitation
Study linking diabetes genes to better care
This trial is studying people with certain types of diabetes, including diabetes that starts after age 30 or in pregnancy, to help improve clinical care. You may be invited if your diabetes type fits the study’s genetic and antibody criteria.
CopenhagenAges 18 years+ - NCT05251415Recruiting
Study of rare autoimmune diseases with blood and medical samples
This trial collects clinical and lab information (like blood and medical history) from people with rare autoimmune diseases, especially when symptoms are unusual. It aims to better understand what causes these illnesses and how newer treatments may help.
ToulouseAges 6–99 - NCT05139784Recruiting
Study of immune changes in people with type 1 diabetes and other diabetes
This study looks at immune (defense system) and blood-sugar changes in people with type 1 diabetes, and in some other diabetes or autoimmune hormone conditions. It includes people who will have a specific abdominal surgery so doctors can safely study lymph node tissue.
Bobigny, Île-de-France RegionAges 1 year+ - NCT05139706Recruiting
Study immune side effects after cancer immunotherapy
This study looks at how immune-related side effects happen in people treated with certain cancer immunotherapies. It also includes some healthy volunteers and people who already have similar autoimmune conditions, to better understand and compare these reactions.
Montreal, QuebecAges 18–100 - NCT05041309Enrolling by invitation
Long-term follow-up after gene-modified cell treatment
This study is for people who have already received a special kind of cell therapy that involved modifying their genes. The purpose is to keep track of their health over a longer period of time to see how they are doing after the treatment.
Gilbert, ArizonaAges Any age
Hear when a new Autoimmunity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for autoimmunity?
- Yes. Clin2 currently lists 341 recruiting autoimmunity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a autoimmunity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a autoimmunity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.