Clinical trials
Biopsy clinical trials
Below are recruiting biopsy clinical trials, each written for real people, not researchers. We’re tracking 961 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04742608Recruiting
Liquid blood tests to diagnose thyroid nodules or cancer
This study tests whether a blood “liquid biopsy” can help diagnose thyroid cancer or hard-to-tell thyroid nodules without needing extra procedures. It may help confirm what’s going on before or around planned thyroid surgery.
Los Angeles, CaliforniaAges 18 years+ - NCT04775134Recruiting
Checking leftover COVID virus after recovery
This study looks for whether small amounts of the COVID virus are still present in the lungs after infection. It may help doctors understand how long the virus can remain and inform future care, using tissue removed during a medically needed lung procedure.
LeuvenAges 18 years+ - NCT04797767RecruitingPhase 1/Phase 2
Venetoclax plus CLAG-M for high-risk AML
This trial studies venetoclax combined with CLAG-M chemotherapy to treat adults with high-risk acute myeloid leukemia (AML) or related high-grade blood cancers. It aims to improve control of the disease, especially in people whose AML is considered high risk.
Seattle, WashingtonAges 18 years+ - NCT04807868Recruiting
Liver fat registry for adults with or at risk for fatty liver
This study builds a research registry (and optional test results follow-up) for adults who either need a routine liver biopsy or may have fatty liver risk based on body weight and other health history. It helps researchers learn more about non-alcoholic fatty liver disease (fatty liver not caused by alcohol) and how it may progress.
Orlando, FloridaAges 18 years+ - NCT04845828Recruiting
Sentinel node biopsy versus full node removal in early uterine cancer
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
SeoulAges 20–80 - NCT04853212Recruiting
Study gut microbiome differences in people with spondyloarthritis
This study looks at whether changes in the gut bacteria (called microbiome dysbiosis) are linked to spondyloarthritis. It compares people with the condition to people without it who are already planning a digestive scope for another reason.
Boulogne-BillancourtAges 18 years+ - NCT04870944RecruitingPhase 1/Phase 2
CBL0137 for children with advanced solid or brain tumors
This early-phase study tests CBL0137 in children and teens whose cancer has come back or is not responding to treatment. It is also for some specific hard-to-treat brain tumors, to see if the drug is safe and can work against the cancer.
Birmingham, AlabamaAges 1–21 - NCT04892277RecruitingPhase 1
CD19 CAR-T for adults with hard-to-treat B-cell cancers
This Phase 1 trial tests a lab-made immune therapy (CD19 CAR-T) for adults whose B-cell cancers have come back or did not respond to treatment. It may help your immune system better recognize and attack cancer cells, but it is early research, so benefits and risks are still being defined.
Rochester, MinnesotaAges 18 years+ - NCT04896047Recruiting
Test whether FGF19 helps non-diabetic kidney disease
This study looks at FGF19 to see if it can improve chronic kidney disease in people who do not have diabetes. Participants may receive FGF19 (and may need extra testing such as muscle biopsies).
Pierre-BéniteAges 18–70 - NCT04896684Recruiting
Study collecting gut health information from adults’ scans
This study is looking at people who need an intestinal scope (endoscopy) for gut symptoms or bowel conditions like IBS, IBD, or possible colorectal cancer. Your results may help doctors better understand these long-term conditions and improve follow-up care.
ToulouseAges 18–99 - NCT04919629RecruitingPhase 2
Tested treatments for recurrent ovarian cancer with fluid buildup
This Phase 2 study tests whether adding two medicines—APL-2 plus pembrolizumab or pembrolizumab plus bevacizumab—works better than bevacizumab alone for recurrent ovarian, fallopian tube, or primary peritoneal cancer. It also focuses on people who have symptoms from cancer-related fluid (ascites or pleural effusion).
Buffalo, New YorkAges 18 years+ - NCT04931732Recruiting
Liquid blood test to diagnose brain glioma
This trial checks whether a special blood test can help identify glioma (a type of brain tumor) that is new or coming back. It may help doctors learn more about the tumor using blood, alongside the usual brain scans and planned surgery.
BronAges 18–90 - NCT07137416RecruitingPhase 1
Testing a new combination of cancer drugs for HER2-positive tumors and breast cancer
This trial tests the safety of combining two drugs, CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd), in people with HER2-positive solid tumors or certain types of breast cancer. If you have advanced cancer that hasn't responded to other treatments, this study may be an option.
Boston, MassachusettsAges 18 years+ - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT06732388RecruitingPhase 2
Itraconazole with ablation to prevent esophageal cancer in Barrett's esophagus
This trial tests if adding the antifungal drug itraconazole to standard ablation therapy can help prevent esophageal cancer in people with high-risk Barrett's esophagus. You must have a confirmed diagnosis of Barrett's esophagus with low- or high-grade dysplasia or early-stage cancer, and be planning to have ablation treatment.
Kansas City, KansasAges 18 years+ - NCT06101303Recruiting
Endometriosis pain study using surgery and surveys
This study looks at pain in people with or without endometriosis who are having laparoscopic surgery. Researchers want to understand more about pelvic pain by collecting information before, during, and after surgery.
St Louis, MissouriAges 12–45 - NCT04939051RecruitingPhase 2
Obeticholic acid to prevent Barrett’s esophagus worsening
This Phase 2 trial tests whether obeticholic acid (a medicine) can help stop Barrett’s esophagus from getting worse. You must already be taking acid-suppressing medicine and have non-cancer Barrett’s changes, and the study checks safety and whether the lining improves or stays stable.
Kansas City, KansasAges 18 years+ - NCT04940962Recruiting
Study of fat tissue in obesity and type 2 diabetes
This study looks at a specific receptor (CB1) in abdominal fat tissue to understand how it affects fat-related chemicals in the body. Your participation would involve giving consent and having a tissue sample taken during planned internal (visceral) surgery.
DijonAges 18–80 - NCT04941716RecruitingPhase 2
Acalabrutinib plus venetoclax for hard-to-treat CLL/SLL
This Phase 2 trial studies whether combining acalabrutinib and venetoclax can shrink or control chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or did not respond to prior treatment. It may help by attacking the cancer using two different medicines together.
Seattle, WashingtonAges 18 years+ - NCT04944030Recruiting
Study collects health data for metastatic lung cancer patients
This study collects medical information and test results from people with lung cancer that has spread (or cannot be cured with local treatment). It does not test a new drug; it helps researchers better understand patients’ health and care needs over time.
AngersAges 18 years+ - NCT04947254RecruitingPhase 2
Add niraparib to hormone therapy after prostate radiation
This Phase 2 trial tests whether adding niraparib to standard hormone therapy (androgen ablation) after radiation works better for men with high-risk, localized or locally advanced prostate cancer. It may help control the cancer for longer, while also collecting extra tissue and blood to study why the treatment works or doesn’t.
Houston, TexasAges 18 years+ - NCT04959474Recruiting
Pre-surgery radiation study with or without calorie restriction
This trial looks at whether a planned calorie-reduction diet before surgery can change how early breast cancer responds to a short course of radiation. It may help people understand if diet could improve outcomes alongside standard pre-surgery treatment.
Philadelphia, PennsylvaniaAges 40 years+ - NCT04981509RecruitingPhase 2
Check if 3 medicines help advanced kidney cancer
This Phase 2 trial tests whether combining bevacizumab, erlotinib, and atezolizumab can shrink or control advanced kidney cancer. It’s aimed at people with certain kidney-cancer subtypes (including HLRCC-related cases or papillary kidney cancer) and who have not had many prior targeted or immune treatments.
La Jolla, CaliforniaAges 12 years+ - NCT04989959RecruitingPhase 1
PET/CT scan test in kidney cancer and related conditions
This Phase 1 study tests whether a special PET/CT scan drug ([18F]PT2385) can help doctors see kidney cancer and related tumors. It may help guide diagnosis and treatment decisions, especially in people planning surgery or starting belzutifan.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for biopsy?
- Yes. Clin2 currently lists 961 recruiting biopsy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biopsy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biopsy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.