Clinical trials
Bladder Carcinoma clinical trials
Below are recruiting bladder carcinoma clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06770582RecruitingPhase 2
Adding immunotherapy to radiation for bladder cancer
This trial tests whether adding the immunotherapy drug pembrolizumab to radiation therapy works as well as or better than the usual chemotherapy given with radiation for a type of bladder cancer that has not invaded the muscle. It is for people whose cancer came back or has high-risk features and who would otherwise need to have their bladder removed.
Fayetteville, ArkansasAges 18 years+ - NCT05833867RecruitingPhase 1
Bladder cancer trial combining radiation and Sacituzumab
This Phase 1 study tests whether a new bladder-cancer treatment plan—radiation given at the same time as sacituzumab govitecan—can help people with muscle-invasive bladder cancer without starting with traditional chemo/radiation. Because it’s early-stage, the main goal is safety and learning the best way to use this combination to preserve the bladder.
Cleveland, OhioAges 18 years+ - NCT07067749RecruitingPhase 3
MRI-guided treatment for muscle invasive bladder cancer
This trial uses advanced MRI scanning to guide treatment decisions for muscle invasive bladder cancer. It aims to improve outcomes by personalizing therapy based on detailed imaging.
Rome, RMAges 18 years+ - NCT05969860RecruitingPhase 2
Home cancer treatment vs clinic treatment for advanced cancer
This Phase 2 trial compares giving certain standard cancer infusions at home versus in a clinic. It may help people avoid clinic visits while still receiving the same cancer treatment safely.
Jacksonville, FloridaAges 18 years+ - NCT06995898Recruiting
A new way to screen for cancer
This study tests a new blood test to find cancer early. You will give blood samples and let researchers look at your medical records for one year.
Pleasanton, CaliforniaAges 45–75 - NCT06983210RecruitingPhase 2
Combination treatment for advanced bladder cancer
This trial tests a new drug combination for people with advanced bladder or urinary tract cancer that has not been treated before. The goal is to see if adding AM80 to standard chemotherapy and immunotherapy works better.
Nagoya, Aichi-kenAges 18–79 - NCT06586255RecruitingPhase 1
Immunotherapy and radiation after bladder cancer surgery
This trial tests whether adding radiation therapy to immunotherapy after bladder removal surgery can help prevent cancer from coming back. It's for people with advanced bladder cancer who have already started immunotherapy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07480356RecruitingPhase 3
Testing a new bladder cancer treatment (TARA-002) vs standard chemo
This trial compares a new medicine called TARA-002, given directly into the bladder, to the doctor's choice of standard chemotherapy. It is for people with a high-grade, non-muscle invasive bladder cancer that has not been treated with BCG or has not had BCG recently.
Queen Creek, ArizonaAges 18 years+ - NCT05521698RecruitingPhase 1
Bicalutamide study for early bladder cancer in men
This trial tests whether bicalutamide can help men with non-muscle invasive bladder cancer (an early form that hasn’t spread into muscle). It is a Phase 1 study, meaning the main goal is to see how safe it is and learn how it behaves in the body for this cancer type.
Tucson, ArizonaAges 18 years+ - NCT07029256Recruiting
Ultrasound-guided biopsy for bladder cancer staging
This trial uses an ultrasound-guided needle biopsy to check if bladder cancer has spread beyond the bladder. It may help doctors stage the cancer more accurately before surgery.
Rochester, MinnesotaAges 18 years+ - NCT07717242RecruitingPhase 2
Bladder cancer study testing a new drug combination before surgery
This trial is testing a combination of two drugs (disitamab vedotin and toripalimab) for people with muscle-invasive bladder cancer that has not spread. The goal is to see if this treatment can shrink the tumor before surgery. You may qualify if your tumor has a certain level of a protein called HER2.
Guangzhou, GuangdongAges 18 years+ - NCT06470282RecruitingPhase 1/Phase 2
Drug combo plus radiation for muscle-invasive bladder cancer
This trial tests a combination of two drugs (enfortumab vedotin and pembrolizumab) plus radiation therapy for people with bladder cancer that has grown into the muscle layer. The goal is to see if this treatment can kill the cancer while avoiding the need for bladder removal surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06444815RecruitingPhase 1
Study of VET3-TGI for advanced solid tumors
This trial tests an experimental treatment called VET3-TGI, which is injected directly into tumors. It is for people with advanced solid tumors who have already tried other treatments and are looking for new options.
Los Angeles, CaliforniaAges 18 years+ - NCT06349642Recruiting
Testing a live tumor test for immune therapy response
This trial uses a special test on live tumor samples to see if it can predict how well immune checkpoint inhibitors (a type of immunotherapy) will work for different cancers. It may help doctors choose the best treatment for you.
Phoenix, ArizonaAges 18 years+ - NCT05962541RecruitingPhase 4
Using bladder scans to plan repeat surgery for bladder cancer
This trial checks whether a bladder scan and score (VI-RADS from MRI) can help doctors choose the right way to do a second look surgery for non-muscle-invasive bladder cancer. The goal is to reduce the chance of needing extra (“secondary”) resections while still catching important disease early.
Rome, LazioAges 18 years+ - NCT06537960Recruiting
Later scan images to better see bladder cancer spread
This trial tests whether taking extra, later images during your standard FDG PET-CT scan can give doctors a better view of how far your muscle-invasive bladder cancer has spread. You may be eligible if you are 18 or older, have confirmed muscle-invasive bladder cancer, and are already getting this type of scan.
Suresnes, Île-de-France RegionAges 18 years+ - NCT07492628RecruitingPhase 1
Dual-target cell therapy for advanced bladder cancer
This trial tests a new treatment that uses your own immune cells, called CAR-NK cells, modified to attack two proteins (Nectin-4 and HER2) often found on bladder cancer cells. It is for people whose cancer has spread or cannot be removed by surgery and has not responded to standard treatments like chemotherapy or immunotherapy.
Shenzhen, GuangdongAges 18–75 - NCT06228066RecruitingPhase 2
Lurbinectedin with or without avelumab for small cell bladder cancer
This clinical trial tests a drug called lurbinectedin, given alone or with avelumab (an immunotherapy), for people with small cell bladder cancer or similar high-grade neuroendocrine tumors that have spread. The goal is to see if combining these drugs helps shrink or control the cancer better.
Bethesda, MarylandAges 18–120 - NCT07579195RecruitingPhase 1/Phase 2
Consolidation therapy after EV + pembro in bladder cancer
This trial tests whether adding radiation therapy or bladder-removal surgery (consolidation) after EV + pembrolizumab helps control muscle-invasive bladder cancer that has spread. It is for people whose cancer responded to the initial drug combination.
Seattle, WashingtonAges 18 years+ - NCT05059444Recruiting
Blood test study to watch for cancer coming back
This study looks at whether blood tests can detect signs that cancer may return after curative-intent treatment. You would have blood drawn around your usual follow-up visits for up to 5 years, and your de-identified health data would be shared with study investigators.
Birmingham, AlabamaAges 18 years+ - NCT06173349RecruitingPhase 1
New bladder therapy for BCG-resistant bladder cancer
This trial tests a new treatment for bladder cancer that does not respond to standard BCG therapy. The treatment uses tiny particles (micelles) that deliver a chemotherapy drug directly into the bladder, aiming to destroy cancer cells without needing surgery.
Sacramento, CaliforniaAges 18 years+ - NCT06704191RecruitingPhase 1/Phase 2
In-home chemo for bladder cancer trial
This trial tests if you can receive chemotherapy for bladder cancer at home instead of in the clinic. It is for people with early-stage bladder cancer who are already getting certain types of intravesical (inside the bladder) treatment.
Jacksonville, FloridaAges 18 years+ - NCT07061964RecruitingPhase 2
Immunotherapy and radiation to save the bladder
This trial tests whether combining immunotherapy and low-dose radiation after chemotherapy can help you avoid bladder removal. It's for people whose muscle-invasive bladder cancer has shrunk significantly after initial treatment.
Birmingham, AlabamaAges 18 years+ - NCT06766266RecruitingPhase 1
Irinotecan and Epirubicin for recurring bladder cancer
This trial tests a combination of two chemotherapy drugs (irinotecan and epirubicin) for people whose bladder cancer has come back after prior treatment with a similar drug. The goal is to see if this combination can help shrink or control the cancer.
ChongqingAges 18 years+
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Common questions
- Are there clinical trials for bladder carcinoma?
- Yes. Clin2 currently lists 152 recruiting bladder carcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bladder carcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bladder carcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Urothelial Carcinoma Bladder
- Muscle-Invasive Bladder Carcinoma
- Muscle Invasive Bladder Urothelial Carcinoma
- Non-Muscle Invasive Bladder Urothelial Carcinoma
- Non-Muscle Invasive Bladder Carcinoma
- Metastatic Bladder Urothelial Carcinoma
- Metastatic Bladder Carcinoma
- Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.