Clinical trials · Minnesota
Brain Tumor clinical trials in Minnesota
We’re tracking 16 recruiting brain tumor studies with a site in Minnesota — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Minneapolis, MinnesotaAges Any age - NCT04692337Recruiting
Ommaya device for easier testing of brain tumor fluid
This study places a small device in the brain area (called an Ommaya reservoir) so doctors can collect brain fluid to test tumor markers over time. It may help researchers learn more about brain tumors, while also fitting alongside your planned brain surgery at Mayo Clinic.
Rochester, MinnesotaAges 18 years+ - NCT06322602Recruiting
Brain tumor biopsy with Ommaya reservoir for fluid collection
This study places a small reservoir under your scalp during a brain tumor biopsy to collect fluid samples over time. It may help doctors learn more about your tumor and how it responds to treatment.
Rochester, MinnesotaAges 18 years+ - NCT06667726RecruitingPhase 2
New PET scan for better brain tumor care
This trial studies a special PET scan called 18F-DOPA PET/CT to see if it can help doctors better manage brain tumors. It may be used before surgery, for radiation planning, or when MRI results are unclear.
Rochester, MinnesotaAges 18 years+ - NCT05755399Recruiting
Ultrasound test during brain tumor surgery
This study checks whether a special, painless ultrasound technique can help measure a brain tumor during planned brain surgery. It may help doctors understand tumor location and behavior more accurately while you’re already in the operating room.
Minneapolis, MinnesotaAges 18 years+ - NCT05733312Recruiting
Ultrasound treatment to temporarily open the brain blood barrier
This study looks at using focused ultrasound to temporarily loosen the brain’s “blood barrier” around certain brain tumors, while people still get standard surgery. It aims to help doctors learn how safe the approach is and collect blood/fluid samples during the operation.
Rochester, MinnesotaAges 18 years+ - NCT06810544RecruitingPhase 1/Phase 2
Study of TNG456 for tumors with MTAP loss
This trial tests a new drug called TNG456, alone or with another drug (abemaciclib), for people whose tumors have lost the MTAP gene. It aims to see if the combination can shrink tumors or slow their growth.
Rochester, MinnesotaAges 18 years+ - NCT03750227RecruitingPhase 3
Radiation before or after brain tumor surgery
This study compares giving focused, high-precision radiation before or after surgery for brain metastases. It aims to see which timing works best to control tumors and improve outcomes.
Rochester, MinnesotaAges 18 years+ - NCT04684368RecruitingPhase 2
New treatment study for children and young adults with NGGCT brain tumors
This Phase 2 study tests a new treatment approach for certain brain tumors called NGGCT in children and young adults. It may help improve outcomes by targeting tumors in specific brain locations and using tumor marker tests to guide care.
Minneapolis, MinnesotaAges 3–29 - NCT04692324Recruiting
Test spinal fluid tests to help identify brain tumor types
This study looks at spinal fluid (cerebrospinal fluid, or CSF) to find markers that may signal a brain or spinal tumor or related abnormal growth. If you have a suspected tumor near the CSF spaces, these results may help doctors better classify what’s going on.
Rochester, MinnesotaAges Any age - NCT05432804RecruitingPhase 1/Phase 2
Selinexor added to temozolomide for recurring brain glioblastoma
This trial studies whether adding selinexor to the standard chemotherapy temozolomide (with radiation) can better treat glioblastoma that has come back after prior treatment. If you meet specific tumor, health, and lab requirements, the goal is to slow tumor growth or improve symptoms.
Rochester, MinnesotaAges 18 years+ - NCT07091396Enrolling by invitation
Home brain stimulation to improve thinking and language
This trial tests a safe, mild electrical stimulation device (tDCS) that you can use at home. It may help improve your thinking or language after a stroke, brain tumor, or other brain condition.
Rochester, MinnesotaAges 18 years+ - NCT05057702Recruiting
Personalized surgery-focused treatment plan for relapsed brain cancer
This study tests a personalized treatment plan for children and young adults whose medulloblastoma or ependymoma has come back. It aims to guide doctors using new tissue from surgery or biopsy after earlier treatments are fully finished.
Minneapolis, MinnesotaAges 1–39 - NCT05538130RecruitingPhase 1
Study medicine for BRAF-mutated advanced solid tumors
This Phase 1 trial studies how PF-07799544 works and what dose is safest in people with advanced cancer that has a specific genetic change called BRAF V600. You may receive it alone or with another treatment, depending on the tumor group, to see if it can treat the cancer.
Saint Louis Park, MinnesotaAges 16 years+ - NCT06788886Recruiting
Breathing practice for brain and mental health in cancer and other illnesses
This study tests a simple breathing practice to see if it can improve brain health and mental well-being for people with cancer, multiple sclerosis, or their caregivers. You will do light exercises and answer questionnaires, and some participants will also have an MRI brain scan.
Rochester, MinnesotaAges 18–85 - NCT05786924RecruitingPhase 1/Phase 2
Targeted cancer drug study for RAS/RAF mutation-positive tumors
This Phase 1/2 study tests S241656 (a targeted cancer medicine) in people whose cancers have certain “RAS/RAF” gene changes. It may help shrink tumors or control cancer growth, and also finds the safest dose and best way to use the drug.
Minneapolis, MinnesotaAges 18 years+
Where these studies are running in Minnesota
Institutions with a site for the recruiting brain tumor studies listed above.
- Mayo Clinic · 11 studies
- Children's Hospitals and Clinics of Minnesota - Minneapolis · 2 studies
- University of Minnesota · 2 studies
- Abbott-Northwestern Hospital
- HealthPartners Frauenshuh Cancer Center
- Methodist Hospital Inpatient Pharmacy
- Regions Hospital
- University of Minnesota Masonic Cancer Center
What taking part in a brain tumor study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Brain Tumor trials in other states
Common questions
- Are there brain tumor clinical trials in Minnesota?
- Yes. We're currently tracking 16 recruiting brain tumor studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a brain tumor study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New brain tumor studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.