Clinical trials
Breast Cancer Patients clinical trials
Below are recruiting breast cancer patients clinical trials, each written for real people, not researchers. We’re tracking 2,205 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06495515RecruitingPhase 2
Dalpiciclib plus toremifene for advanced HR+ breast cancer
This trial tests a combination of two drugs (dalpiciclib and toremifene) as a first treatment for advanced breast cancer that is hormone receptor positive and HER2 negative. It may be an option if you have not had hormone therapy for advanced disease or if your cancer came back more than a year after prior treatments.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT03740503Recruiting
Study genes in people who respond unusually to treatment
This study looks at stored tumor samples to understand why some people respond much better or much worse than expected. The goal is to learn what the tumor’s genes might be telling doctors about response to treatment.
Toronto, OntarioAges 18 years+ - NCT07123649RecruitingPhase 2
Customizing mammogram schedules for older breast cancer survivors
This study looks at how often older breast cancer survivors (80+) should get mammograms. It aims to make screening more personalized so women get the right amount of imaging.
Boston, MassachusettsAges 80 years+ - NCT07113613RecruitingPhase 2
Can some breast cancer patients skip extra radiation after surgery?
This trial tests whether women who have a complete response to chemotherapy before breast-conserving surgery can safely skip a special radiation boost to the tumor bed. It aims to reduce unnecessary treatment side effects while maintaining good outcomes.
Nanjing, JiangsuAges 30–75 - NCT04342546Recruiting
Radiation skin side-effect test after mastectomy with implant
This trial looks at a test meant to predict how likely you are to develop side effects from radiation to the chest wall after mastectomy. It is designed for people getting immediate breast reconstruction using an implant, so treatment planning may be safer and more personalized.
DijonAges 18 years+ - NCT07492641RecruitingPhase 3
A new drug plus letrozole for advanced HR+ breast cancer
This trial tests a new medicine (BGB-43395) combined with letrozole against the usual CDK4/6 inhibitor plus letrozole. It is for people with advanced or metastatic HR-positive, HER2-negative breast cancer who have not yet had treatment for advanced disease.
Birmingham, AlabamaAges 18 years+ - NCT06265025RecruitingPhase 1/Phase 2
GM103 injection for advanced solid tumors that can't be removed
This trial tests an experimental drug called GM103 that is injected directly into tumors. It is for people with advanced solid tumors that have not responded to other treatments and cannot be surgically removed.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT06580002RecruitingPhase 2
Can Riluzole Help with Chemo Brain? A Pilot Study
This study tests if a medicine called riluzole (currently used for ALS) can help with 'chemo brain' – memory and thinking problems after cancer treatment. It is for people who feel their mental sharpness has declined after breast cancer therapy, certain chemotherapies, or brain radiation.
Orange, CaliforniaAges 18 years+ - NCT07381985Enrolling by invitation
Managing hereditary cancer risk in rural areas
This study tests a way to help people with inherited cancer gene mutations manage their health, especially if they live in rural areas. You join if you found out about the mutation more than a year ago.
Burlington, VermontAges 18 years+ - NCT06516289RecruitingPhase 2
Neoadjuvant treatment for BRCA-mutated HER2-negative breast cancer
This trial tests a combination of two oral medications (HRS-1167 and famitinib) with or without an immunotherapy drug (camrelizumab) before surgery for women with a BRCA gene mutation and HER2-negative breast cancer. It aims to see if these drugs can shrink tumors before surgery.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06185205RecruitingPhase 2
Accelerated high-dose radiation for early breast cancer
This trial tests a very short, high-dose radiation treatment given directly to the breast after lumpectomy. It aims to make radiation more convenient by finishing in just a few days instead of weeks, possibly with fewer side effects.
Richmond, VirginiaAges 45–79 - NCT05274048RecruitingPhase 1
Neratinib plus antibody-drug for HER2-positive stomach or esophagus cancer
This early-phase trial tests neratinib together with an antibody-drug to treat advanced HER2-positive gastro-esophageal (stomach/esophagus) cancer that can’t be removed by surgery. It’s for people whose cancer has progressed after at least one HER2-targeted treatment, aiming to shrink tumors and improve outcomes.
Palo Alto, CaliforniaAges 18 years+ - NCT06889610RecruitingPhase 2
Ablation plus drug therapy for advanced solid tumors
This trial tests combining a liver tumor ablation procedure with systemic drugs for people with advanced colorectal, breast, or melanoma cancer that has spread to the liver. The goal is to see if this approach can help when standard treatments have stopped working.
ShanghaiAges 18–80 - NCT05440929Recruiting
Testing a breast-cancer prognostic tool with U.S. clinicians
This study checks how acceptable, appropriate, and easy to use a metastatic breast-cancer “prognostic calculator” is for clinicians. It may help clinicians use the tool in real practice to support care decisions for people with metastatic breast cancer.
Chapel Hill, North CarolinaAges Any age - NCT05890287Recruiting
Chidamide plus hormone therapy after chemotherapy for breast cancer
This trial studies chidamide added to standard hormone (endocrine) therapy to help prevent breast cancer from coming back after initial chemotherapy. It may help by keeping cancer under control for longer in people with HR-positive, HER2-negative breast cancer who respond to first-line treatment.
TianjinAges 18–75 - NCT07331753Recruiting
Fat grafting with back muscle flap for breast reconstruction
This study tests if combining fat grafting with a muscle flap from the back improves breast reconstruction results after a mastectomy. It may help women who had a mastectomy and are now looking for delayed reconstruction.
Sohag, Sohag GovernorateAges 18 years+ - NCT07214532Recruiting
Using a blood test to guide breast cancer therapy
This study tests whether a blood test can help decide when to start additional hormone-blocking therapy for early-stage breast cancer. It aims to see if starting therapy only when the test detects cancer DNA is as effective as giving it to everyone.
Phoenix, ArizonaAges 18 years+ - NCT06953882RecruitingPhase 2
Skipping chemo after surgery for ER+ HER2- breast cancer
This study tests whether some people with a certain type of breast cancer (ER-positive, HER2-negative) can safely skip chemotherapy. After surgery, they receive a targeted pill (ribociclib) plus hormone therapy instead. The goal is to see if this approach works just as well with fewer side effects.
New Haven, ConnecticutAges 18 years+ - NCT05547529RecruitingPhase 3
Chemo and radiation before surgery versus chemo alone for esophageal cancer
This trial studies whether adding radiation to chemotherapy before surgery works better for people with operable (resectable) squamous cell esophageal cancer. It aims to improve outcomes by comparing two different treatment plans before the operation.
MoscowAges 18–70 - NCT05178498Recruiting
Diet and inflammation score in women at high breast cancer risk
This study looks at whether a person’s diet that tends to cause more body inflammation is linked to future breast cancer risk. It may help researchers understand how eating patterns could affect risk in people already considered high-risk.
Columbus, OhioAges 18 years+ - NCT07292246Recruiting
HandX-assisted endoscopic mastectomy study for breast cancer
This trial tests a new, less invasive way to remove breast tissue using a small camera (endoscope) with a device called HandX. It's for women who need a mastectomy for early-stage breast cancer, DCIS, or to reduce high risk, and aims to see if it's safe and works well.
Glyfada, AtticaAges 18 years+ - NCT07060014RecruitingPhase 1
Testing NALIRIFOX for advanced appendix and small intestine cancer
This trial tests a combination of four chemotherapy drugs (NALIRIFOX) as a first treatment for people with advanced appendix or small intestine cancer. It aims to see if this combination is safe and effective.
Houston, TexasAges 18 years+ - NCT06636682RecruitingPhase 2
Vaccine for men with high-risk prostate cancer after surgery
This trial tests a personalized vaccine (FK-PC101) given after prostate removal surgery for men with high-risk prostate cancer. It aims to see if the vaccine can help prevent the cancer from coming back without the need for additional hormone therapy or radiation.
Chicago, IllinoisAges Any age - NCT05911958RecruitingPhase 2
Study drug before surgery for HER2-low, HR-positive breast cancer
This trial tests SHR-A1811 given before surgery (neoadjuvant treatment) for breast cancer that is hormone-receptor positive (HR-positive) and HER2-low. It aims to shrink or control the cancer early and see how well this approach works compared with standard care.
Zhengzhou, HenanAges 18–70
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Common questions
- Are there clinical trials for breast cancer patients?
- Yes. Clin2 currently lists 2,205 recruiting breast cancer patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.