Clinical trials
Breast Cancer Stage I clinical trials
Below are recruiting breast cancer stage i clinical trials, each written for real people, not researchers. We’re tracking 1,170 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT07850869Recruiting
Virus injection plus immunotherapy for advanced breast cancer
This study tests a new approach that combines a modified virus (H101) injected directly into the tumor with immunotherapy drugs that help your immune system fight cancer. It is for people with advanced breast cancer who have already tried standard treatments and could not continue chemotherapy.
Guangdong, FoshanAges 18–75 - NCT06425874Recruiting
Study on how social factors affect well-being after breast surgery
This study looks at how things like income, education, and support systems affect the quality of life and emotional well-being of younger women (ages 18-50) after breast cancer surgery. The goal is to better understand and address these factors.
Guangzhou, GuangdongAges 18–50 - NCT06389006RecruitingPhase 2
Combination therapy before surgery for HER2-low, hormone-positive breast cancer
This trial tests a combination of two drugs (disitamab vedotin and toripalimab) followed by chemotherapy before surgery for people with a specific type of breast cancer that is hormone receptor-positive and HER2-low. The goal is to see if this treatment can shrink the tumor and improve outcomes.
Shanghai, Fudan University Shanghai Cancer CenterAges 18 years+ - NCT07844473Recruiting
Magtrace dye to guide surgery for early breast cancer
This trial tests using a special dye called Magtrace to help surgeons find and remove the cancer and check nearby lymph nodes during breast-conserving surgery. It might help make the surgery more precise and avoid extra procedures.
MadinahAges 18 years+ - NCT07826338Recruiting
Mobile app support for breast cancer patients starting chemotherapy
This study tests a smartphone app that provides support and information to women with breast cancer who are starting chemotherapy for the first time. The app may help manage symptoms and improve your experience during treatment.
Izmir, İzmirAges 18 years+ - NCT06472583RecruitingPhase 2
Immunotherapy and radiation before breast cancer surgery
This trial tests giving immunotherapy combined with a precise, high-dose radiation boost before surgery for HER2-negative breast cancer. The goal is to see if this approach can improve outcomes, especially for cancers that are more advanced or have spread to a few other spots in the body.
GliwiceAges 18 years+ - NCT04790305RecruitingPhase 4
Huaier granules with standard therapy for early triple-negative breast cancer
This trial looks at whether adding Huaier granules to usual after-surgery treatment can improve outcomes for people with high-risk early-stage triple-negative breast cancer. It focuses on whether the added supplement is safe and helpful after standard care.
Hefei, AnhuiAges 18–70 - NCT07803081Recruiting
Radiotherapy after breast surgery without lymph node biopsy
This study looks at how well radiation therapy works for women with early-stage breast cancer who had breast-conserving surgery but did not have their underarm lymph nodes removed. It aims to understand long-term outcomes and help guide future treatment decisions.
SeoulAges 19 years+ - NCT04353557Recruiting
Blood test monitoring in early-stage breast cancer
This trial uses a special blood test to track cancer signals (called ctDNA) during and after treatment for early breast cancer. It aims to see whether monitoring these signals can help guide follow-up and treatment decisions.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06236269RecruitingPhase 2
Sacituzumab Govitecan for HR+/HER2- advanced breast cancer
This trial tests a drug called Sacituzumab Govitecan for people with HR+/HER2- advanced or metastatic breast cancer that has stopped responding to a CDK4/6 inhibitor. It looks at whether the drug can slow down the cancer and requires you to have a tumor biopsy.
Badalona, BarcelonaAges 18 years+ - NCT06508216RecruitingPhase 1/Phase 2
New drug combo for early relapsed triple-negative breast cancer
This trial tests experimental drugs for people with triple-negative breast cancer that came back within 12 months of finishing initial treatment. The goal is to see if these drugs are safe and can shrink or slow the cancer.
VillejuifAges 18 years+ - NCT07797218RecruitingPhase 3
Comparing two drug combinations before breast cancer surgery
This study is comparing two different drug combinations given before breast cancer surgery. The goal is to see which one shrinks tumors more effectively. This type of treatment is called 'neoadjuvant' therapy.
ShanghaiAges 18–70 - NCT07796880RecruitingPhase 2
Study of a new drug with hormone therapy before breast cancer surgery
This trial tests a new drug called culmerciclib when given with hormone therapy before breast cancer surgery. The goal is to see if this combination can shrink tumors and improve outcomes for patients with hormone-receptor-positive, HER2-negative breast cancer.
Guangzhou, GuangdongAges 18–70 - NCT04679454Recruiting
One-dose pre-surgery radiation for early breast cancer
This study tests whether giving a single dose of radiation before breast surgery can be safe and effective for early-stage breast cancer. It may help by shrinking or treating the tumor right before the operation, depending on your case.
MilanAges 18 years+ - NCT07780240Recruiting
Understanding arm band pain after breast cancer surgery
This study looks at how common axillary web syndrome (a rope-like band in the armpit after breast cancer surgery) is, who gets it, and how it affects arm function. It aims to help doctors better predict and manage this condition.
Istanbul, BAGCILARAges 18–80 - NCT07768436RecruitingPhase 2
cmf chemotherapy for breast cancer in older adults
This trial tests a combination of three older chemotherapy drugs (cyclophosphamide, methotrexate, and fluorouracil, called CMF) for adults 70 and older with breast cancer. The goal is to see if this treatment is effective and well-tolerated in this age group.
Basking Ridge, New JerseyAges 70 years+ - NCT03827317Recruiting
Scan to see HER2 in breast cancer with a new tracer
This study tests a new PET scan tracer to show where HER2-positive breast cancer cells may be in the body. It may help doctors better “map” HER2 activity, including in people with HER2-positive or HER2-negative cancer.
LondonAges 18 years+ - NCT07751783Recruiting
Exercise program for cancer survivors
This trial helps people who have finished cancer treatment start a supervised exercise routine to improve their health. It tests whether a structured program with professional guidance is safe and helpful.
Kaohsiung, TaiwanAges 18–80 - NCT07752238Recruiting
Predicting outcomes for newly diagnosed metastatic breast cancer
This study uses information from women with newly diagnosed breast cancer that has spread (metastatic) to create a tool that helps predict how the disease may progress. By looking at your medical records, they hope to improve care and help future patients.
Szombathely, Vas CountyAges 18 years+ - NCT06185972RecruitingPhase 2
MRI-guided ultrasound radiation for breast and chest cancer
This trial tests a new way to give radiation therapy using MRI imaging and ultrasound to make the radiation more targeted and potentially safer. If you have chest-wall or breast cancer and are already scheduled for radiation, this approach might offer a more precise treatment option.
Toronto, OntarioAges 18 years+ - NCT06633601RecruitingPhase 1
Ultrasound and microbubbles with radiation for breast cancer
This trial tests a new way to combine radiation therapy with ultrasound and tiny bubbles to treat breast cancer that has spread to the chest wall or is advanced. It aims to make radiation more effective and safer.
Toronto, OntarioAges 18 years+ - NCT07723209Recruiting
Radiation after no lymph node sampling in breast cancer
This trial tests whether radiation therapy alone is safe and effective for women 40 and older with early-stage breast cancer who have not had lymph node sampling. It aims to simplify treatment while maintaining good outcomes.
New York, New YorkAges 40 years+ - NCT07718841Recruiting
Blood test monitoring for early-stage breast cancer
This study uses a simple blood test called liquid biopsy to monitor cancer DNA in people with early-stage breast cancer before and during treatment. The goal is to see if this test can help guide treatment and improve outcomes.
San Sebastián, GuipúzcoaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer stage i?
- Yes. Clin2 currently lists 1,170 recruiting breast cancer stage i studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer stage i trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer stage i trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Anatomic Stage IV Breast Cancer AJCC v8
- Anatomic Stage III Breast Cancer AJCC v8
- Anatomic Stage II Breast Cancer AJCC v8
- Anatomic Stage I Breast Cancer AJCC v8
- Early-stage Breast Cancer
- Breast Cancer Stage III
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.