Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07426822RecruitingPhase 2
Preventing Rash and Diarrhea with Capivasertib for Breast Cancer
This trial tests whether giving a combination of the drugs capivasertib and fulvestrant, along with medicines to prevent rash and diarrhea, can help treat hormone receptor-positive breast cancer that has a PIK3CA, AKT1, or PTEN change. It's for people whose cancer has spread or is locally advanced and can't be removed with surgery.
New Haven, ConnecticutAges 18 years+ - NCT07426809Recruiting
A study to improve lumpectomy surgery with real-time imaging
This study tests a new imaging tool that helps surgeons see cancer margins in real time during a lumpectomy, aiming to reduce the need for a second surgery. It is for women with early-stage breast cancer who are planning a lumpectomy.
Beaumont, DublinAges 18 years+ - NCT06813456Recruiting
Improving HER2 detection in breast cancer with new testing method
This trial studies a more precise way to measure HER2 levels in breast cancer tissue. It may help identify patients whose cancer is HER2-low or HER2-zero, so they can get more targeted treatment.
Bologna, BolognaAges 18 years+ - NCT06773143Recruiting
Esketamine for sleep quality during breast cancer chemo
This trial tests whether a low dose of esketamine can improve sleep quality in women with breast cancer who are receiving neoadjuvant chemotherapy. If you have trouble sleeping during treatment, this study may find a new way to help.
Nanjing, JiangsuAges 18–65 - NCT07422870Recruiting
Registry for granulomatous mastitis
This study is creating a registry (a database) for people with a rare inflammatory breast condition called granulomatous mastitis. It aims to learn more about the disease and how it affects people, without testing any new treatments.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07410169RecruitingPhase 2/Phase 3
Oxygen therapy for chemo-related nerve pain in breast cancer
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can reduce nerve pain caused by the chemotherapy drug nab-paclitaxel in breast cancer patients. It may help women who have finished chemo and are still dealing with numbness, tingling, or pain in their hands or feet.
Guangzhou, GuangdongAges 18–75 - NCT06818370Recruiting
Coconut oil for preventing hair loss during chemo
This trial tests whether applying coconut oil to the scalp can reduce hair loss caused by a common breast cancer chemotherapy combination (doxorubicin and cyclophosphamide). It may help women who are about to start this specific chemo regimen.
Ankara, YenimahalleAges 18–65 - NCT07394218RecruitingPhase 2
Tumor DNA Blood Test to Guide Breast Cancer Treatment
This trial tests whether using a blood test for tumor DNA can help doctors decide the best treatment for people with HER2-negative breast cancer that has spread. It focuses on a type of therapy called an antibody-drug conjugate (ADC) and aims to personalize your care.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07378306RecruitingPhase 2
Fasting-mimicking diet with chemo-immunotherapy for triple-negative breast cancer
This trial tests whether adding a special low-calorie diet (called a fasting-mimicking diet) to standard chemotherapy and immunotherapy can help treat triple-negative breast cancer before surgery. It aims to see if this combination makes the treatment work better.
Guangzhou, GuangdongAges 18–70 - NCT07362914RecruitingPhase 3
Steroid cream for hand-foot skin reactions from chemo
This trial tests whether a corticosteroid cream can prevent or reduce hand-foot skin reactions caused by liposomal doxorubicin (a type of chemotherapy) in breast cancer patients. If you are starting this chemo and are concerned about skin side effects, this study may offer a way to manage them.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07362485Recruiting
Finding sentinel nodes during mastectomy with dye
This trial tests if a special dye (indocyanine green) can find the first lymph nodes (sentinel nodes) during mastectomy. It may help improve staging for women with early breast cancer who need or choose mastectomy.
Zwolle, OverijsselAges 18 years+ - NCT07369505RecruitingPhase 1
A study of Sapu003 for advanced tumors sensitive to mTOR
This trial tests a new drug, Sapu003, in people with certain advanced cancers that may respond to mTOR-targeted therapy. It is looking at two groups: postmenopausal women with a type of breast cancer (HR+/HER2-), and adults with kidney, liver, neuroendocrine, or TSC-related tumors. The goal is to see if Sapu003 is safe and effective.
AdelaideAges 18 years+ - NCT07359404Enrolling by invitationPhase 2
Sacituzumab Govitecan plus Bevacizumab for metastatic TNBC
This trial tests a combination of two drugs, Sacituzumab Govitecan and Bevacizumab, for people with advanced triple-negative breast cancer that has already been treated. The goal is to see if the combination works better than standard treatments.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07351487RecruitingPhase 2
Chemo plus immunotherapy and anti-angiogenic drug for TNBC before surgery
This trial tests whether adding sintilimab (an immunotherapy) and bevacizumab (a drug that blocks blood supply to tumors) to standard chemotherapy before surgery can improve outcomes for women with stage II or III triple-negative breast cancer. It may help your immune system fight the cancer more effectively.
HefeiAges 18–75 - NCT07335081RecruitingPhase 2
ctDNA in HER2-positive early breast cancer before surgery
This trial is testing whether monitoring ctDNA (genetic material from the tumor in your blood) can help guide treatment for HER2-positive breast cancer before surgery. It is for people with early-stage (Stage II or III) disease who have not yet started treatment.
ShanghaiAges 18–70 - NCT07332975Recruiting
Blood test for tumor DNA in early triple-negative breast cancer
This study is for people with early-stage triple-negative breast cancer (TNBC) that has not been treated yet. Researchers want to see if tracking tumor DNA in your blood can help guide treatment decisions. You would receive standard chemotherapy and surgery, plus give blood samples.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07311083Recruiting
Lifestyle program for triple-negative breast cancer patients
This study tests a lifestyle program (diet, exercise, and support) for women with triple-negative breast cancer who are getting chemotherapy plus immunotherapy before surgery. The goal is to see if healthy habits can help during treatment.
Essen, North Rhine-WestphaliaAges 18–75 - NCT06050109Recruiting
Continuing Ovarian Suppression After 5 Years
This trial checks if staying on ovarian function suppression (OFS) therapy beyond 5 years helps prevent breast cancer from coming back. It's for women with early-stage, hormone-sensitive (HR+ HER2-) breast cancer who have already completed 5 years of OFS.
Wuhan, HubeiAges 18–60 - NCT07290153Recruiting
Psychological health and immunotherapy for TNBC
This study looks at how psychological factors and the immune system affect treatment response in women with triple-negative breast cancer. Researchers will use questionnaires and biological samples to understand these links.
Shanghai, Please SelectAges 18–70 - NCT07283107Enrolling by invitation
Increasing mammogram rates in Singaporean women
This trial tests different ways to encourage women in Singapore to get a mammogram (a breast X-ray to check for cancer early). You may be eligible if you are a Singaporean citizen aged 50–69, use the NUHS app, and have either never had a mammogram or are overdue for your next one.
SingaporeAges 50–69 - NCT07283692RecruitingPhase 2
New drug combo for triple-negative breast cancer before surgery
This trial tests a new drug, serplulimab, combined with standard chemotherapy (paclitaxel and carboplatin) given before surgery for triple-negative breast cancer. The goal is to see if this combination can shrink tumors more effectively.
ShanghaiAges 18–70 - NCT06880029RecruitingPhase 1/Phase 2
Timing of chemo and immunotherapy for breast cancer
This trial is testing whether the time of day you receive chemotherapy and pembrolizumab (immunotherapy) affects how well they work against triple-negative breast cancer. It's for people who will get these treatments before surgery.
Vila Nova de Gaia, RegiãoAges 18–75 - NCT07278726Recruiting
Targeted removal of only suspicious lymph nodes for early breast cancer
This trial is testing a targeted surgical approach to remove only the suspicious lymph nodes under the arm for people with early-stage, hormone receptor positive, HER2 negative breast cancer. The goal is to see if this less extensive surgery is safe and effective when there is limited lymph node involvement.
Bologna, ItalyAges 18–90 - NCT07257679RecruitingPhase 4
Gentle touch for arm swelling after breast cancer surgery
This study tests a gentle hand-on technique (called Gentle Touch) to see if it helps reduce arm swelling in women who developed lymphedema after breast cancer surgery. It may offer a new way to manage this side effect.
Roma, RMAges 30–75
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,417 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.