Clinical trials
Breast - Female clinical trials
Below are recruiting breast - female clinical trials, each written for real people, not researchers. We’re tracking 3,615 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05716516RecruitingPhase 2
Estradiol pill for ER-positive advanced breast cancer
This trial studies whether an estradiol (a form of estrogen) treatment can help people with ER-positive advanced breast cancer. It is mainly for post-menopausal women whose cancer is not curable and has already been treated with endocrine (hormone) therapies.
Lebanon, New HampshireAges 18 years+ - NCT05710705Recruiting
Bioimpedance monitoring in belly-flap breast reconstruction
This study tests a method called bioimpedance to monitor blood flow in the transplanted belly tissue during breast reconstruction surgery. It may help doctors know when the blood supply is stable, which could lead to safer recovery.
AmiensAges 18 years+ - NCT05740787Recruiting
Study of thinking changes after chemotherapy for breast cancer
This study looks at how chemotherapy may affect thinking and memory in people with HER2-negative breast cancer. It uses brain scans during or after chemotherapy to understand these changes and potentially guide support in the future.
AberdeenAges 18 years+ - NCT05721976Recruiting
Grandmother–daughter lifestyle program for certain cancer survivors
This pilot study tests a supportive program for grandmothers who finished breast, endometrial, or ovarian cancer treatment and their adult daughters. It aims to encourage healthier habits, including physical activity, using phone-based support and Spanish/English materials.
Miami, FloridaAges 21 years+ - NCT05741164RecruitingPhase 2
Propranolol plus pembrolizumab for hard-to-treat breast cancer
This Phase 2 trial studies whether adding propranolol to pembrolizumab can “re-sensitize” tumors and slow cancer in triple-negative breast cancer that no longer responds to checkpoint immunotherapy. It may help some people whose cancer has grown despite prior pembrolizumab and chemotherapy.
Atlanta, GeorgiaAges 18 years+ - NCT05736367Recruiting
Study tumor metabolism in certain types of breast cancer surgery
This study looks at how breast cancer cells use energy and nutrients in hormone-receptor positive, HER2-negative tumors during planned surgery. It may help researchers understand the cancer better by comparing tumor tissue with nearby normal tissue.
New Brunswick, New JerseyAges 18 years+ - NCT05738187Recruiting
Cryotherapy for repeat head and neck cancer after prior radiation
This pilot study tests whether cooling treatment on the tumor area (cryotherapy) can control a repeat head/neck cancer that can’t be removed and has already been treated with radiation. It also checks safety, especially in areas that have received radiation before.
StrasbourgAges 18 years+ - NCT05745857RecruitingPhase 2
Scan for early esophagus cancer using infused antibody dyes
This Phase 2 study uses special drug dyes (bevacizumab and cetuximab, each tagged for imaging) during an esophagus scope to help doctors find very early abnormal cells, like low- or high-grade pre-cancer and superficial cancer. If you qualify, the goal is earlier detection and better targeting during diagnosis and treatment.
Groningen, Provincie GroningenAges 18 years+ - NCT05739591Recruiting
Long-term follow-up for people treated in a breast cancer trial
This study checks how well a previous early breast cancer treatment works over the long term and monitors safety. It may help you and future patients by providing long-term results from the original trial.
Innsbruck, TriolAges 18 years+ - NCT05717842Recruiting
Kidney and liver transplant candidates get a scan at surgery
This trial studies whether a specific scan taken around the time of a combined liver-and-kidney transplant can help doctors assess the kidney(s) that will be used. You might be eligible if you are already listed for both transplants and can safely complete the scan.
Indianapolis, IndianaAges 18 years+ - NCT05723250Recruiting
Rural early cancer care coaching and education program
This study tests an educational “care coordination” program to help people living in rural Vermont manage care during the early stages of breast, lung, or colon cancer treatment. It may help you feel more supported and organized while starting or preparing for chemotherapy.
Burlington, VermontAges 18 years+ - NCT05722002RecruitingPhase 4
Compare pain-med plans after low-risk surgery
This study tests which pain-medication plan works best and has the fewest side effects after certain low-risk surgeries. You may be assigned to receive opioid-based, NSAID-based, or acetaminophen-based pain control depending on your situation.
Ann Arbor, MichiganAges 18 years+ - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05375968RecruitingPhase 2
Test blood-flow changes in POTS after meals
This Phase 2 study looks at how blood pools in the belly veins when you stand or eat, in people with POTS (postural tachycardia syndrome). The goal is to understand what’s driving symptoms like feeling nearly faint and whether this helps guide better care.
Nashville, TennesseeAges 18–50 - NCT05687110RecruitingPhase 1
Testing novobiocin for tumors with DNA repair gene changes
This Phase 1 study tests whether novobiocin is safe and finds the best dose for people whose tumors have specific DNA repair gene mutations. It may help if your cancer is hard to treat with standard options, including certain patients who already tried PARP inhibitors.
Duarte, CaliforniaAges 18 years+ - NCT05684965RecruitingPhase 1/Phase 2
Study drug for advanced solid cancers after standard treatments
This Phase 1/2 trial tests XTX301, a study treatment, in people with advanced solid tumors (cancers) that have already been treated and are not controlled by standard options. It may help if your cancer matches one of the study groups and you meet safety and test-tissue requirements.
Sacramento, CaliforniaAges 18 years+ - NCT05688605RecruitingPhase 1/Phase 2
Study of MRG003 for EGFR-positive advanced cancers
This trial tests a drug called MRG003 for people with certain advanced cancers that have a specific protein, EGFR. The drug targets the cancer cells that have this protein, which may help stop the cancer from growing.
Guangzhou, GuangdongAges 18–75 - NCT05706129RecruitingPhase 1/Phase 2
Testing targeted imaging and therapy for advanced solid tumors
This early-phase study tests two radioactive medicines that first help doctors see tumors and, in some parts of the study, treat them. It may help people with advanced, hard-to-remove cancers that have a specific tumor marker (CA IX).
MelbourneAges 18 years+ - NCT05683418RecruitingPhase 1
Study of a new drug for PIK3CA-mutated HR+ HER2- breast cancer
This early-stage study tests the safety and tolerability of TOS-358 in women with HR-positive, HER2-negative breast cancer that has a specific gene change (PIK3CA). It may help learn whether this targeted treatment is safe enough to move forward.
Chicago, IllinoisAges 18 years+ - NCT05696626RecruitingPhase 3
Test a new pill plus abemaciclib versus standard therapy
This Phase 3 study compares lasofoxifene plus abemaciclib versus fulvestrant plus abemaciclib for ER-positive, HER2-negative breast cancer that has an ESR1 mutation. It looks for better tumor control in people whose cancer has progressed on hormone therapy (an aromatase inhibitor) and who meet specific safety and testing requirements.
Scottsdale, ArizonaAges 18 years+ - NCT05703256Recruiting
Brain training with feedback to help depression
This trial tests a type of brain training called amygdala neurofeedback to reduce depression symptoms. It may help by teaching your brain patterns to become less “stuck” in depression-related activity.
Pittsburgh, PennsylvaniaAges 18–55 - NCT05696691RecruitingPhase 2/Phase 3
Ketamine with a crisis plan for suicidal thoughts in the ER
This study tests whether ketamine plus a structured crisis-response plan can help reduce suicidal thoughts for adults admitted from the ER. It also aims to make care in the emergency setting more consistent and effective.
San Antonio, TexasAges 18–70 - NCT05691348Recruiting
Same-day surgery for uncomplicated acute appendicitis
This trial studies whether removing an uncomplicated appendix in one day (without an overnight hospital stay) is safe and practical. It may help patients recover faster at home, if they meet the trial’s safety requirements.
Nice, Alpes MaritimesAges 15–74 - NCT05694559Recruiting
Genetic risk screening and counseling for Black adults
This study connects Black adults to genetic counseling and genetic testing to learn whether they may have an inherited cancer risk. It uses a simple risk screening tool, including visits by phone or video, to guide next steps.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for breast - female?
- Yes. Clin2 currently lists 3,615 recruiting breast - female studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast - female trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast - female trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.