Clin2
NCT05703256Possibly a fitRecruiting

Brain training with feedback to help depression

Major Depressive Disorder

Part of Mental health clinical trials.

This trial tests a type of brain training called amygdala neurofeedback to reduce depression symptoms. It may help by teaching your brain patterns to become less “stuck” in depression-related activity.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years to 55 years
Study type
Interventional

Who can take part

  • You are between 18 and 55 years old
  • You have a main diagnosis of depression (MDD) and you feel depressed now
  • You can read and understand English questionnaires and sign consent
  • You are not taking most mood/brain-affecting medicines recently (antidepressants are allowed if stable)
  • You can safely do MRI scans (not claustrophobic and no MRI safety issues like metal/shrapnel)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06050070Recruiting
Using Real-Time Brain Imaging to Help Depression

This study tests whether real-time brain imaging (fMRI) can help people with depression learn to change their brain activity. You will receive feedback on your brain signals while thinking positive or neutral thoughts.

Ann Arbor, Michigan
NCT06417437Recruiting· Phase 4
Brain-computer interface test for depression

This trial tests a non-invasive brain-computer interface (BCI) to help people with depression. It may be a good fit for teenagers and adults who are right-handed, Han Chinese, and have moderate to severe depression without other major health problems.

Shanghai, Shanghai Municipality
NCT05977439Recruiting
Brain training for depression recovery

This study uses brain imaging and stimulation to help people with depression learn how to regulate their emotions better. It aims to find out if targeting specific brain networks can improve symptoms.

Charleston, South Carolina
NCT05523817Recruiting
Brain scan targeting to improve specific depression symptoms

This study uses brain-signal targeting (likely with MRI) to see whether it can improve certain symptoms of depression. You may be able to join if you’re 18–65 and currently have a depressive episode, and if you can safely complete the scan.

Boston, Massachusetts
NCT05640089Recruiting
Brain training with fMRI feedback for depression

This trial tests whether using real-time brain scan feedback (fMRI neurofeedback) can help reduce depressive symptoms. You may be eligible if you have depression that is still active despite being on antidepressant medicine.

Maastricht
NCT07159061Recruiting
Brain training for depression using neurofeedback

This study tests whether a brain training technique called neurofeedback can help treat depression. By showing your brain activity in real time on a screen, you may learn to control the brain patterns linked to depression and feel better.

Philadelphia, Pennsylvania

Hear when a new Major Depressive Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.