Clinical trials
Breast Surgery clinical trials
Below are recruiting breast surgery clinical trials, each written for real people, not researchers. We’re tracking 200 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05327608Recruiting
Time-restricted eating during chemo before breast cancer surgery
This study tests whether eating only during a certain window of time each day (time-restricted eating) can improve outcomes for people with early-stage breast cancer who are getting chemotherapy before surgery. It may help with treatment side effects and overall health.
Cherry Hill, New JerseyAges 18 years+ - NCT07236658Recruiting
Using AI to detect arm problems after breast cancer surgery
This trial uses artificial intelligence (a computer program) to help predict arm and shoulder problems that can happen after breast cancer surgery. It aims to find these issues early so they can be treated better.
AnkaraAges 18 years+ - NCT06678776Recruiting
Study of breast fascia during mastectomy or reduction
This trial studies the natural structure of connective tissue (fascia) in the breast during surgery. It may help doctors better understand how to preserve important structures during mastectomy or breast reduction.
Guangzhou, GuangdongAges Any age - NCT05919108RecruitingPhase 2
Neratinib before surgery for HER2-mutated invasive lobular breast cancer
This Phase 2 trial tests neratinib given before surgery to treat stage I–III invasive lobular breast cancer that has a specific HER2 mutation and is hormone-receptor positive. It may help shrink the tumor and improve control of cancer before and after surgery.
Atlanta, GeorgiaAges 18 years+ - NCT07308717RecruitingPhase 4
Gabapentin for mastectomy recovery
This trial tests if gabapentin improves recovery after mastectomy. It studies how giving the drug before surgery affects pain and healing.
Basking Ridge, New JerseyAges 18–65 - NCT07843212Recruiting
Nerve block for breast cancer surgery
This study tests a nerve block (called SPSIP) given during breast cancer surgery to see if it reduces inflammation and affects a protein called TLR4, which may help with pain and recovery. If you're having breast cancer surgery, this might help you heal better with less discomfort.
Çorum, ÇorumAges 18–85 - NCT07672392Recruiting
Exercise after breast reconstruction surgery
This trial tests whether a structured exercise program after DIEP flap breast reconstruction helps improve physical fitness compared to standard care. It may help women recover strength and well-being after surgery.
Beaumont, DublinAges 18 years+ - NCT04888975Recruiting
Device study for one-arm swelling after lymph surgery
This study tests a medical device (Dayspring Technology) to reduce swelling in the arm caused by breast cancer treatment and lymph surgery. You may be eligible if you have one-sided arm swelling after lymphatic surgery and meet safety checks for the device.
Palo Alto, CaliforniaAges 18 years+ - NCT05973864RecruitingPhase 2
Capecitabine plus pembrolizumab after TNBC surgery and chemo
This Phase 2 trial studies whether adding capecitabine to pembrolizumab after surgery can lower the risk of cancer coming back in people with triple-negative breast cancer that didn’t fully respond to earlier treatment. It’s meant for patients whose tumor was removed but still showed remaining cancer after chemo-immunotherapy.
AmiensAges 18 years+ - NCT05933733Recruiting
Salvage treatment for breast cancer that returned locally
This trial looks at how well “salvage” treatments work for breast cancer that has come back only in the local area (like the chest wall or nearby lymph nodes), without spreading to distant organs. It also tracks side effects to better understand the risks and benefits for patients who need additional treatment.
SeoulAges 18–100 - NCT06556654Recruiting
Tissue reinforcement for breast reconstruction study (REDEFINE)
This study tests a new tissue reinforcement device (like a mesh) used during two-stage implant-based breast reconstruction after a mastectomy. It is designed for women having their first reconstruction and may help support the implant and improve healing.
Scottsdale, ArizonaAges 22 years+ - NCT07546695Recruiting
Axillary lymph node surgery choices for HER2+ and triple-negative breast cancer
This study examines the best surgical approach for removing underarm lymph nodes in patients with HER2-positive or triple-negative breast cancer who have received chemotherapy before surgery and still have cancer in their lymph nodes. The goal is to understand whether removing more lymph nodes improves outcomes for these patients.
BaselAges Any age - NCT07085442Recruiting
Audit of targeted lymph node biopsy for early breast cancer
This study looks at how well a special type of lymph node biopsy works for people with early breast cancer that has spread to a small number of lymph nodes. It aims to see if this approach is effective and safe, which may help guide future treatment decisions.
BurnleyAges 18 years+ - NCT07830446Recruiting
Pain relief injections for breast surgery
This trial tests whether a special numbing injection (called a fascial plane block) given before breast surgery can reduce pain after the operation. It compares this to standard pain management to see if it helps you recover with less discomfort.
BursaAges 18–80 - NCT07783386Recruiting
Comparing nerve block volumes for breast surgery pain
This study compares different volumes of a nerve block (SPSIP) for pain relief after breast surgery. It aims to see if one volume provides better pain control with fewer side effects.
Nilufer, BursaAges 18–75 - NCT07674836Recruiting
Comparing two nerve blocks for chronic pain after breast surgery
This study tests two types of nerve blocks (SPSIP and ESP blocks) to see which one works better for long-term pain after a single-sided breast surgery like mastectomy. It aims to find a safer, more effective way to manage chronic pain after surgery.
İzmit, KocaeliAges 18–65 - NCT07631468Recruiting
Breast Surgery Follow-Up Study with Imaging Technology
This study follows patients who had breast surgery using special imaging tools (MOLLI, SPY-PHI, or SPY AGENT GREEN) to see how well these tools help surgeons and how patients recover. Your information helps doctors understand if these tools work safely and effectively.
Jacksonville, FloridaAges 18 years+ - NCT07561853Recruiting
Nerve block comparison for pain relief after mastectomy
This study compares two different numbing treatments (nerve blocks) to see which provides better pain relief during and after breast surgery. If you are having a mastectomy, this trial may help reduce your pain after the operation.
SakaryaAges 25–65 - NCT07541040Recruiting
Nerve Blocks for Breast Surgery Pain Relief
This trial tests two different nerve-block techniques to reduce pain after breast surgery. The study compares a serratus block with an ESP block—both are injections of numbing medication near nerves—to see which works better for managing pain without heavy opioid use.
İzmit, KocaeliAges 18–65 - NCT07390448Recruiting
Comparing two pain block methods for mastectomy
This trial compares two nerve block techniques to control pain after breast cancer surgery. If you are having a mastectomy or breast-conserving surgery with lymph node removal, this study may help reduce your pain and improve recovery.
CairoAges 18–60 - NCT07002541Recruiting
Nerve block comparison for breast surgery pain
This study tests two different nerve-block methods (PECS-II and ESP) to see which better reduces painkiller use during breast surgery. A special monitor guides how much pain medicine you need. The goal is to help you recover with less opioid side effects.
IstanbulAges 18–80 - NCT06989372Enrolling by invitation
Nerve blocks for pain relief after chest surgery
This study compares two different nerve block methods to see which provides better pain control. If you qualify, you may receive one of these blocks before your chest surgery.
CairoAges 18–65 - NCT06934564Recruiting
Cutting unnecessary tests before low-risk surgeries
This study helps surgical teams cut down on unnecessary tests before common low-risk surgeries, like breast lump removal, gallbladder removal, or hernia repair. It aims to improve patient care by reducing extra, unneeded procedures.
Ann Arbor, MichiganAges 18 years+ - NCT06711965Recruiting
Custom molds for breast reconstruction shaping
This trial tests custom 3D-printed molds to help shape breast tissue during reconstruction. It is for people who are already planning a DIEP or TRAM flap after mastectomy.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for breast surgery?
- Yes. Clin2 currently lists 200 recruiting breast surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.