Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 860 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06712524Recruiting
Comparing surgery types for granulomatous mastitis
This study compares different surgical methods for treating granulomatous mastitis, a rare inflammatory breast condition. It aims to find which approach works best for patients who can safely have surgery.
Wuhan, HubeiAges 18 years+ - NCT07203911Recruiting
Ultrasound guidance for oral cancer surgery
This trial tests whether surgeons can use ultrasound during surgery to better guide the removal of oral cancer. It may help ensure all cancer is removed while sparing healthy tissue.
Stanford, CaliforniaAges 18 years+ - NCT04553770RecruitingPhase 2
Trastuzumab deruxtecan with or without anastrozole for early breast cancer
This Phase 2 study tests whether trastuzumab deruxtecan alone or combined with anastrozole can control early-stage breast cancer that is HER2-low and hormone-receptor positive. It aims to improve outcomes after initial surgical treatment by targeting cancer cells that may have low levels of HER2.
Fullerton, CaliforniaAges 18 years+ - NCT06802991Recruiting
Optimized post-discharge care for older colon cancer patients
This trial tests better nutrition and follow-up care for older patients after colon cancer surgery. It focuses on people who are somewhat frail and at risk for poor nutrition, to see if extra support at home can improve recovery.
HerlevAges 65 years+ - NCT07194616Recruiting
Rectal cancer blood test study before surgery
This trial is studying a blood test (CTC) for people with rectal cancer that hasn't spread to other parts of the body. It aims to see how the test relates to treatment outcomes after surgery.
OlomoucAges 18 years+ - NCT04103372Recruiting
MRI check for early rectal cancer or large polyps
This trial uses a special MRI before treatment to better understand early rectal cancer or suspicious large polyps. It may help doctors choose care that avoids bigger surgery when possible.
Reading, BerkshireAges 16–100 - NCT07222241Recruiting
Comparing numbing methods for Mohs surgery on face or scalp
This study compares two ways of numbing the skin during Mohs surgery for skin cancer on the face or scalp. It aims to find which method causes less pain and is more satisfying for patients.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06938360Recruiting
Breast-conserving surgery for central breast cancer study
This trial compares breast-conserving surgery (removing only the tumor and nearby tissue) to total mastectomy (removing the whole breast) for women with breast cancer in the central area of the breast. The goal is to see if the less extensive surgery works just as well.
Xi'an, ShaanxiAges 18–70 - NCT07162506RecruitingPhase 2
Comparing further treatment options for esophageal cancer after chemo-immunotherapy
This trial compares two approaches for people with esophageal cancer that has shrunk or disappeared after initial chemotherapy combined with immunotherapy. It looks at whether adding targeted radiation (DCRT) or surgery is better. The goal is to find the most effective next step for eligible patients.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07352930Recruiting
Fluorescence-guided system for breast cancer surgery margins
This trial tests a new imaging system that helps surgeons see if cancer cells remain after breast-conserving surgery. It may reduce the need for a second surgery by giving real-time feedback on the removed tissue.
Guangzhou, GuangdongAges 18 years+ - NCT07597837Recruiting
Breast Cancer Surgery Outcomes Study
This study collects information about breast cancer surgery outcomes—with or without reconstruction—to help doctors understand what works best for patients. By participating, you'll contribute to research that may improve care for future patients.
Boston, MassachusettsAges 18 years+ - NCT06686459Recruiting
AI-assisted single-session radiotherapy after breast-conserving surgery
This trial tests a new approach where all radiation is given in one session using AI guidance. It is for women who had breast-conserving surgery with lymph node removal and need radiation afterward.
GuangzhouAges 18–70 - NCT05694338Recruiting
Study frailty during major surgery for gut cancer
This trial studies how “frailty” affects people with gastrointestinal (gut) cancer who are about to have major surgery, sometimes after chemotherapy or other treatment beforehand. It may help doctors better prepare and support patients through surgery.
East Corning, New YorkAges 18 years+ - NCT06349590RecruitingPhase 1/Phase 2
Diet before colon cancer surgery to reduce recurrence
This trial tests whether a specific diet before colon cancer surgery can change the bacteria in your gut to help prevent the cancer from coming back or spreading. Patients who are eligible will follow the diet for a short time before their operation.
Chicago, IllinoisAges 18 years+ - NCT07235098Recruiting
Music therapy for lung cancer surgery patients
This trial tests whether listening to music in the hospital can help reduce distress and pain after surgery for lung cancer. If you are having a minimally invasive surgery (keyhole surgery) to remove part of your lung, you may be able to join.
Bellinzona, Canton TicinoAges 18 years+ - NCT06698146Recruiting
Liver transplant for colorectal cancer that spread to the liver
This trial tests a special approach for colorectal cancer that has spread to the liver: first removing the liver tumor, then doing a partial liver transplant, and later removing more liver tissue. The goal is to see if this can help people who otherwise have limited options.
Chicago, IllinoisAges 18 years+ - NCT06964438Recruiting
Post-surgery electrical muscle stimulation study for colorectal or stomach cancer
This trial tests if using a mild electrical device on your legs after surgery can help you recover faster. It is for people with colorectal or stomach cancer who are having curative abdominal surgery.
Derby, DerbyshireAges 18 years+ - NCT07025213Recruiting
Exercise and diet study for endometrial cancer before surgery
This study tests whether combining exercise with a special diet can improve how your body processes energy (metabolism) before you have surgery to remove the cancer. It is for people with early-stage endometrial cancer who haven't yet started treatment.
México, TlalpanAges 18–65 - NCT07140172Recruiting
Radiation or surgery for node-positive breast cancer
This trial compares two treatments for people with breast cancer that has spread to the lymph nodes: radiation therapy to the armpit or surgery to remove the lymph nodes. The goal is to see which approach works best after a tailored surgery to remove the most suspicious lymph nodes.
Bethesda, MarylandAges 18 years+ - NCT07214584Recruiting
Using blood and cervical tests to track cervical cancer treatment response
This trial checks how well cervical cancer responds to surgery, radiation, and chemotherapy by measuring HPV DNA and RNA in blood and cervical mucus. It aims to improve monitoring during treatment.
Gainesville, FloridaAges 18–89 - NCT06483295Recruiting
Mobile app support after lung cancer surgery
This study uses a mobile internet platform (WeChat) to check on how patients are doing after lung cancer surgery. It aims to improve your recovery and quality of life by collecting updates on your health.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07412379Recruiting
Predicting recovery after cancer surgery for older adults
This study looks at how older adults (65+) with digestive tract cancers respond to surgery aimed at a cure. Researchers want to see what factors affect recovery and quality of life after the operation.
BogotáAges 65 years+ - NCT05191485Recruiting
Helping lung cancer patients decide about genetic testing
This study tests a shared decision-making approach to help people with lung adenocarcinoma decide whether to get molecular (genetic) testing. It aims to improve understanding and support better choices about testing and possible targeted treatments.
Chengdu, SichuanAges 18 years+ - NCT05851534Recruiting
Pre-surgery risk reduction for pancreatic surgery
This study helps people going for planned pancreatic cancer surgery (with or without chemo beforehand) by focusing on controllable risk factors before the operation. The goal is to improve safety and outcomes after surgery.
's-HertogenboschAges 18 years+
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Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 860 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.