Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06577441RecruitingPhase 2
Adding enasidenib to usual care for higher-risk MDS with IDH2 mutation
This trial tests whether adding enasidenib (a targeted pill) to the standard chemotherapy (cedazuridine-decitabine) works better than the chemotherapy alone for people with higher-risk myelodysplastic syndrome (MDS) whose cells have a specific change in the IDH2 gene.
Berkeley, CaliforniaAges 18 years+ - NCT07437963RecruitingPhase 1/Phase 2
Iberdomide plus chemoimmunotherapy for neuroblastoma that returned or did not respond
This trial tests adding a new drug called iberdomide to an existing chemoimmunotherapy regimen for children and young adults with neuroblastoma that has come back or not responded to treatment. The goal is to see if the combination is safe and more effective than current treatments.
Oakland, CaliforniaAges 1–30 - NCT07001449Recruiting
Pain education for chronic muscle or joint pain
This study tests a type of pain education that focuses on communication to help people with long-term muscle or joint pain. It aims to see if learning about pain in a new way can help reduce symptoms and improve quality of life.
Lamia, Central GreeceAges 18–65 - NCT06281080Recruiting
New robotic tool for removing early bladder tumors
This trial tests a new robotic system to remove bladder tumors in one piece (en-bloc resection) for people with early-stage, non-muscle invasive bladder cancer. It may offer a more precise surgical option for eligible patients.
ShatinAges 18–75 - NCT05484973Recruiting
Portable scalp cooling to help prevent chemotherapy hair loss
This study tests whether a portable cooling cap system can reduce hair loss for women with breast cancer who are planning certain chemotherapy treatments. It may help you keep more of your hair while you receive chemotherapy.
Tucson, ArizonaAges 21 years+ - NCT06246357RecruitingPhase 2
Testing adrenal gland function with a special scan
This trial uses a special PET scan (68Ga-PentixaFor) to check how well your adrenal glands are working if you have high aldosterone or cortisol levels. It helps doctors see if the glands are making too much hormone, which may guide treatment.
Bethesda, MarylandAges 18–120 - NCT07714538Recruiting
Breath test for detecting gastrointestinal cancers
This study tests whether a simple breath test can help detect different types of gastrointestinal cancers earlier. If you have been recently diagnosed with one of these cancers or have concerning abdominal symptoms but clear test results, your breath may help teach us how to spot these cancers sooner.
Maidstone, KentAges 18 years+ - NCT07657104Recruiting
HPV screening for women in the emergency department
This study offers free HPV testing to women who visit the emergency department and haven't been screened recently. It aims to catch early signs of cervical cancer so they can get treated sooner.
New Brunswick, New JerseyAges 30–65 - NCT04933435Recruiting
Image-guided radiation plus liver procedures for non-surgical liver cancer
This trial studies a combination approach—special, image-guided radiation and liver procedures—for liver cancer patients who cannot have surgery. It may help shrink tumors while protecting liver function by using planned, targeted treatment.
Durham, North CarolinaAges 18 years+ - NCT07673887RecruitingPhase 3
Study of a new drug combo for advanced stomach cancer
This trial tests a new drug called ASP2138 combined with chemotherapy and pembrolizumab for people with advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery or has spread. It may help if your tumor has certain markers (CLDN18.2 and PD-L1) and you haven't had prior chemotherapy for advanced disease.
Saint Louis Park, MinnesotaAges 18 years+ - NCT07012044RecruitingPhase 1
Cedazuridine and decitabine after stem cell transplant for childhood leukemia
This trial tests if adding two chemotherapy drugs (cedazuridine and decitabine) along with a growth factor (filgrastim) can help prevent leukemia from coming back after a stem cell transplant. It is for children and young adults with high-risk acute myeloid leukemia who are in remission after transplant.
Birmingham, AlabamaAges Up to 21 years - NCT06157463Recruiting
FAPI imaging for newly diagnosed rectal cancer
This trial tests a new imaging agent called 68Ga-FAPI to see how well it finds rectal cancer and guides treatment. It's for people with new stage II or III rectal cancer who are about to start neoadjuvant therapy (treatment before surgery).
TaoyuanAges 18 years+ - NCT07616856Recruiting
Evaluating LumiSystem for cancer surgery margins
This study tests a device called LumiSystem that helps doctors check if all cancer cells are removed during breast cancer surgery. The goal is to see if using it improves surgery outcomes.
Mobile, AlabamaAges 18 years+ - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT07089225Recruiting
Using a cannabis journal app to track symptoms in cancer care
This study asks cancer patients who use cannabis to track their symptoms and cannabis use with a smartphone app. The goal is to learn how cannabis affects symptom management during cancer treatment.
Scarborough, MaineAges 18 years+ - NCT07886320RecruitingEarly Phase 1
Adapalene gel for skin irritation from radiation
This trial tests a gel applied to the skin to see if it helps prevent or reduce the painful skin irritation that can happen after radiation therapy. It may be an option for people with breast cancer or head and neck cancer who are about to start radiation.
Kunming, YunnanAges Any age - NCT07884877RecruitingPhase 2
PULSAR radiotherapy plus immunotherapy for advanced liver cancer
This trial combines a special type of radiation therapy (PULSAR) with immunotherapy (drugs that help your immune system fight cancer) for people with advanced liver cancer that cannot be removed by surgery. The goal is to see if this combination can better control the cancer and improve outcomes.
SeoulAges 19 years+ - NCT07886606RecruitingEarly Phase 1
CBD for opioid use disorder and chronic pain
This study tests whether a CBD (cannabidiol) supplement, when taken along with your usual buprenorphine treatment, can help reduce chronic pain and improve your overall response to treatment for opioid use disorder. You would take the CBD for about 12 weeks and participate in study visits that check your progress.
West Haven, ConnecticutAges 18–70 - NCT05718726Recruiting
Infection risk after spleen removal surgery
This study looks at how often infections happen after spleen removal during surgery for cancer in the belly. It aims to help doctors better protect patients from serious infections.
Basingstoke, HampshireAges 18–79 - NCT07861282Recruiting
Home exercise program for recovery after lung cancer surgery
This study tests a home-based exercise program delivered through a smartphone or computer to help you recover after lung cancer surgery. It may improve your strength, stamina, and overall recovery.
Seville, AndalusiaAges 18–80 - NCT07052630Recruiting
Planning advance care after stem cell transplant
This study tests a program that helps stem cell transplant survivors plan their future care with their doctors. It uses a website and a patient navigator to guide you through conversations about your goals and values.
Seattle, WashingtonAges 18 years+ - NCT05476939RecruitingPhase 3
BIOMEDE 2.0 trial for DIPG and similar brainstem gliomas
This phase 3 study tests targeted treatments (ONC201 or everolimus) for children with DIPG or similar diffuse midline brain tumors, based on the tumor’s genetic markers. It aims to improve outcomes by matching treatment to the tumor biology and comparing approaches in a randomized way.
BrusselsAges 6 months+ - NCT06898996Recruiting
Stool test study for Lynch syndrome colon screening
This trial tests a new stool-based test (FIT) to see if it can help find colon cancer early in people with Lynch syndrome. You will collect stool samples at home and complete surveys before your regular colonoscopy.
Chicago, IllinoisAges 20–80 - NCT06764316RecruitingPhase 1
Safety study of BAY 3547926 for advanced liver cancer
This trial tests a new drug called BAY 3547926 for people with advanced liver cancer that cannot be removed with surgery or has not responded to other treatments. The goal is to see if the drug is safe and how well it works.
Dothan, AlabamaAges 18 years+
Hear when a new Cancer (With or Without Metastasis) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,078 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.