Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004245RecruitingPhase 1
Study of new drug for advanced solid tumors with certain genetic markers
This trial is testing a new oral medication, VVD-133214, for people with advanced solid tumors that have a specific genetic feature called MSI-high or dMMR. The study will see if the drug is safe and effective when given alone or with other drugs like bevacizumab or pembrolizumab.
Tucson, ArizonaAges 18 years+ - NCT07535008Recruiting
Dental Cleaning to Prevent Graft-Versus-Host Disease
This study tests whether professional dental cleaning after a stem cell transplant can help prevent chronic graft-versus-host disease (GVHD), a condition where transplanted immune cells attack your body. You'll receive dental cleanings and be followed for one year to see if this simple preventive step reduces GVHD complications.
Seattle, WashingtonAges 18 years+ - NCT07437950RecruitingPhase 2
Comparing treatment lengths for venetoclax in older adults with newly diagnosed acute myeloid leukemia
This study tests whether a shorter or longer course of the drug venetoclax works better for older adults with a type of blood cancer called acute myeloid leukemia (AML) who are not healthy enough for intensive chemotherapy. The goal is to find the best treatment duration to control the cancer while reducing side effects.
Coeur d'Alene, IdahoAges 60 years+ - NCT06669104Recruiting
Chest surgery using the Medtronic Hugo robot
This study tests whether a robotic system (Medtronic Hugo) can safely help surgeons perform chest surgery with small cuts. If you need chest surgery and are in good health, you may be able to join.
Hong KongAges 18–80 - NCT05828069RecruitingPhase 2
Tovorafenib for young people with worsening Langerhans cell histiocytosis
This Phase 2 trial tests tovorafenib (DAY101) to treat children and young people whose Langerhans cell histiocytosis (LCH) is getting worse, came back, or did not respond to prior treatment. It may help by targeting certain gene changes found in the LCH.
Birmingham, AlabamaAges 6 months–22 years - NCT07735611Recruiting
Comparing robotic bronchoscopy systems for examining lung spots
This study compares two robotic bronchoscopy systems used to examine lung spots or nodules. Participation involves having your scheduled procedure, and researchers will evaluate which system works better.
Cleveland, OhioAges 18 years+ - NCT07493304RecruitingPhase 3
Preventing blood clots in people with cancer
This trial tests a new anticoagulant medication to treat and prevent blood clots in patients with active cancer. You may qualify if you have a recent clot in your leg or lungs and are already taking a blood thinner.
Hialeah, FloridaAges 18 years+ - NCT06172296RecruitingPhase 3
Dinutuximab plus transplant for high-risk neuroblastoma
This trial tests adding a targeted drug called dinutuximab to standard chemotherapy, surgery, and a stem cell transplant for children and young adults with a new diagnosis of high-risk neuroblastoma. The goal is to see if this combination helps more patients stay in remission.
Birmingham, AlabamaAges Up to 30 years - NCT07356154RecruitingPhase 1/Phase 2
Combination treatment for leukemia that has returned or not responded
This study tests two experimental drugs, revumenib and mezigdomide, for people with acute leukemia that has not responded to treatment or has come back. The goal is to see if this combination can help control the disease and improve outcomes.
Duarte, CaliforniaAges 12 years+ - NCT06581432RecruitingPhase 2
Zongertinib for advanced cancers with HER2 changes
This trial tests a new pill called zongertinib for people with advanced cancers that have HER2 changes. It may help when other treatments have stopped working, and it targets the HER2 protein to slow or stop tumor growth.
Anchorage, AlaskaAges 18 years+ - NCT07884474Recruiting
Remote saliva collection for childhood leukemia survivors
This study tests whether it is easy and acceptable for childhood leukemia survivors, their siblings, and caregivers to collect saliva samples at home and send them to researchers. It aims to understand how well this remote method works for future research.
Memphis, TennesseeAges 8–18 - NCT07882888RecruitingPhase 2
Immunotherapy drugs with cetuximab for treatable mouth cancer
This trial tests a combination of two immunotherapy drugs (iparomlimab and tuvonralimab) plus cetuximab for people with oral cancer that can be removed by surgery. The goal is to see if this treatment shrinks tumors and helps patients before their operation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06421155Recruiting
MRI scans of the brain for children and young adults with leukemia
This study uses a special type of magnetic resonance imaging (MRI) to look at the brain of people with acute leukemia. It aims to see if this MRI technique can help doctors better understand the effects of leukemia and its treatment on the brain.
Cleveland, OhioAges Up to 30 years - NCT06395441RecruitingPhase 3
Wisconsin ginseng for cancer-related fatigue
This study tests whether a daily dose of Wisconsin ginseng can help reduce tiredness and improve energy in people who have had or are currently receiving treatment for cancer. It aims to find out if this natural supplement can safely improve fatigue without interfering with their cancer care.
Albert Lea, MinnesotaAges 18 years+ - NCT07455955RecruitingPhase 2
Personalized nausea control for early breast cancer chemo
This trial offers a personalized anti-nausea (antiemetic) plan based on your genetic profile. It's for Chinese women starting their first chemo for early breast cancer, aiming to find the best way to prevent nausea and vomiting during treatment.
Hong KongAges 18–74 - NCT07099898RecruitingPhase 3
Study of a new drug for relapsed small cell lung cancer
This study tests a new drug (GSK5764227) for people whose extensive-stage small cell lung cancer has gotten worse after platinum chemotherapy combined with immunotherapy. The goal is to see if this targeted treatment can help shrink tumors and control the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06917911RecruitingPhase 2
Testing two drug additions to standard chemotherapy for a type of acute myeloid leukemia
This trial tests whether adding venetoclax or gemtuzumab ozogamicin to the usual chemotherapy helps people with a specific genetic type of acute myeloid leukemia (AML) respond better. It may improve chances of remission.
Birmingham, AlabamaAges 18–59 - NCT07468695Recruiting
Comparing one vs two heat treatments for cervical precancer in Kenya
This study tests whether using one or two heat probes is better at removing precancerous cells from the cervix in women living with HIV. It aims to find a simpler, effective way to treat cervical precancer and prevent cancer.
NairobiAges 25–49 - NCT06253338Recruiting
Genes and radiation protection study for untreated cancer
This study looks at whether your genes can help predict how radiation affects your body. It is for people with head, neck, or chest cancer who have not had any previous cancer treatment.
Essen, Germany / NRWAges 18 years+ - NCT07696572Recruiting
Testing a new device for EUS procedures
This trial is studying a new tool called the RIVOS™ EUS access device, which is used during a type of internal ultrasound called endoscopic ultrasound (EUS). The goal is to see how well it works for people who need this procedure.
Orlando, FloridaAges 18 years+ - NCT07690852Recruiting
Environmental exposures and breast cancer risk study
This study looks at how environmental exposures might affect breast cancer risk. It includes women at average risk, high risk, or those diagnosed with breast cancer before age 50, as well as healthcare providers.
Duarte, CaliforniaAges 18 years+ - NCT07431827RecruitingPhase 3
Study of pembrolizumab plus calderasib for KRAS G12C lung cancer after surgery
This trial tests a combination of two drugs (pembrolizumab and calderasib) after surgery for people with a specific type of lung cancer gene mutation called KRAS G12C. It aims to see if this therapy can help prevent the cancer from coming back.
Ciudad Autónoma de Buenos Aires, Buenos AiresAges 18 years+ - NCT07228273RecruitingPhase 2
A new drug combo for AML and high-risk MDS
This trial combines three standard chemotherapy drugs (fludarabine, cytarabine, idarubicin) with a targeted therapy (venetoclax) to treat acute myeloid leukemia (AML) and a related condition called MDS with high blast counts. The goal is to see if adding venetoclax improves results.
Portland, OregonAges 18–65 - NCT07332507RecruitingPhase 1
Testing teclistamab for recurrent plasmablastic lymphoma
This trial tests a new drug called teclistamab for people with plasmablastic lymphoma that has come back or not responded to standard treatments. The goal is to see if teclistamab can shrink tumors and control the disease.
Duarte, CaliforniaAges 18 years+
Hear when a new Cancer (With or Without Metastasis) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,078 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.